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0:00
right, everybody, welcome back to the
0:02
number one podcast in the world,
0:04
the all -in podcast after a triumphant
0:06
week last week. We had an
0:08
amazing episode. Thanks to Larry
0:10
Summers and Ezra Klein for joining
0:12
us for the great tariff
0:14
debate number four episode in the
0:16
world last week. And,
0:19
man, we got a banger ready for
0:21
you today before I get to that couple
0:23
of quick plugs. Did you call the DNC
0:25
to clean up the roadkill, Jason? I'm an
0:28
independent folks. Just I know these guys keep
0:30
trying to pin me as a Democrat. I'm
0:32
an independent critical thinker for life. But
0:34
I do think Ezra is got a
0:36
little PTSD. I haven't from Ezra. the
0:38
DMZ have a roadkill cleanup crew? You
0:41
know, it's amazing. You have an episode
0:43
like that where I thought you'd make great
0:45
progress on dealing with those issues and
0:47
came to some consensus at the end. And
0:49
then every single person universally, if they're
0:51
on the right, oh my God, Sax, you
0:53
can come off, destroyed them. You to
0:55
run the left. The left's position was, oh
0:57
my god, Saxon, Chamath finally got destroyed.
0:59
Anyway, you decide for yourself. We're just here
1:01
to talk about the most important news
1:03
stories. And all
1:06
in some... I think Chamath is right. I
1:08
think they sent the same crew that cleans
1:10
up the armadillos on the road. All
1:15
righty, here we go. September 7th to Angeles.
1:17
There a couple of armadillos left lying on
1:19
the side of the road. All right, okay. All
1:21
is going into its fourth year,
1:24
yada yada. September 7th to 9th,
1:26
apply. All in dot com slash
1:28
summit. Pronouns everywhere. I'm
1:31
trying to clean
1:33
up the pronouns. Shovels
1:35
weren't big enough for all the pronouns.
1:37
Freberg was on Jeopardy! Again, celebrity Jeopardy!
1:39
And I don't want to ruin it
1:42
for you, but he had an amazing
1:44
comeback victory. But really excited to have
1:46
on the program today one of your favorites. He
1:48
was on the show. Pre -election one
1:50
of my favorites Robert F. Kennedy
1:52
is with us again RFK. How are
1:54
you doing? I love the glasses.
1:56
You're gonna make America healthy and again
1:58
and welcome to the program RFK
2:00
Junior. We found out that
2:02
autism is caused mainly by
2:04
this show and we're gonna
2:07
have to take action. Started
2:09
to look at the different
2:11
causes, but we're thinking it is
2:13
the debate between Ezra Klein
2:16
and Larry Summers that is the
2:18
real villain here. Tremendous.
2:37
Everybody knows RFK is going to
2:39
do a great job. He's a little
2:41
bit weird, but wife is a
2:43
smoke show. I mean, an incredible wife,
2:45
RFK Junior. Incredible. Not
2:49
as good. Not as good. Okay. Well, I'm
2:51
trying to land it. Yeah. What am I supposed to do? I'm up against
2:53
some professional. You know, so, uh, welcome
2:55
to the program. moderate so they can
2:57
Yeah. Okay. Here we go. Don't talk over me. Okay. You
3:00
just sit, sit down. Can you do
3:02
what you did last week? Three, go. what's
3:05
that? What's that moderate for narcissists
3:07
who want to add one more
3:09
thing? Yeah, let the experts talk.
3:11
Yes, of course. Why
3:13
can't I talk? Why can't
3:15
I talk? Can
3:18
you please pass the ball? Just pass
3:20
the ball. Here we go. Let's
3:22
welcome our guest, Tim Dillon. He's
3:25
an incredibly funny comedian. He
3:27
has a new special. I'm your
3:29
mother on Netflix. He's the host. of
3:32
the award -winning, now in its
3:34
10th year, Emmy -winning, award
3:37
-winning. He's got the Emmy,
3:39
he's got the Tony, he's still gotta
3:41
get the Grammy and the Oscar, the one, the
3:43
only Tim Dillon of the Tim Dillon Show Pockets.
3:45
Thank you so much, thank you for having
3:47
me. I feel like I'm having a Zoom meeting
3:49
with Doge to prove what I've done in the
3:51
last week. the
3:54
way, this is the last thing
3:56
someone at the EPA sees. It's just
3:58
these four guys. They're just staring a
4:00
guy like Chamath going, well, we
4:02
tested some soil. I
4:04
think we got those numbers
4:06
back. That's what it feels
4:08
like here. I feel like I'm on
4:10
trial just trying to justify. My
4:12
stupid job. Would you
4:14
like eight months severance? Would you like
4:17
to be fired today? Which would you prefer?
4:20
It would have been very funny if
4:22
we actually were just if as
4:24
soon as Tim said that we had
4:26
Steve Davis, but yeah. Well,
4:29
interestingly, I, you
4:31
know, I don't want to speak out of
4:33
school or embarrass our guests, but Tim
4:36
was supposed to join us in February. Yes.
4:38
And like. The star he is, as
4:40
I mentioned, he's got the Emmy, he's got
4:42
the Tony, still working on the Oscar. And
4:45
the Grammy, he was supposed to be with us and
4:47
he canceled last minute and then we found out why.
4:50
He ditched us to spend the day
4:52
with Steve Bannon and going to Steve
4:54
Bannon podcast. Here they are. That's true.
4:56
What is this? Look at that. That's
4:58
Steve Bannon and Timmy. I a
5:00
23 in me and they didn't tell me my
5:02
ethnicity, but the only thing that came back was they
5:04
said that Steve Bannon was my father. Yes.
5:06
And here they are on the cyclone in Brooklyn.
5:08
Beautiful. They went out to Little
5:10
Italy. Little Italy here. By
5:12
the way, they've done a pretty decent
5:14
job. Wrapping up with
5:16
a little hookah. Or maybe a little bit more
5:19
in there. I don't know. Do you think Bannon
5:21
is 420 friendly? You tell us, Timmy.
5:24
I think anything, I mean, Bannon would
5:26
tell you if we could start farming
5:28
marijuana in America and the American working
5:30
class could share in the profits, I
5:32
think he'd be 420 friendly. He
5:35
would be 420 friendly, 420 friendly.
5:37
No Taiwanese marijuana though. Nothing, you
5:39
know, it's gotta be American. Can
5:41
I give a quick shout out, which
5:43
is 10 months ago, Tim Dillon. One
5:46
on the Tucker Carlson show I think
5:48
the title is called Disney boomers and
5:50
the creepy corporations that pretend to love
5:52
you really one of the Best pieces
5:54
of content I watched all of last
5:56
year Nick you should put the link
5:58
in the show notes. Thank you It's
6:00
incredible like thank you the whole thing
6:02
and 10 Two hours while spent I
6:04
would encourage everybody to watch it. It's
6:06
timeless content actually real good cultural observation
6:08
at the moment. It's really good Two
6:10
white guys talking in a in a
6:12
in a garage in Maine seems he
6:14
has a certain way. You know, I
6:16
I went to and did it there
6:18
and he has a way of just
6:20
kind of like slipping you into this
6:22
state of comfort. All of a sudden,
6:24
I just started talking about all the
6:26
money I've lost. He's great. He's great.
6:33
It's like Megan Kelly is great at it, too. I
6:35
just did her thing. And, you
6:37
know, she does it at her house and
6:39
I just show up and she's sitting
6:41
behind the desk and she goes, hi. And
6:43
you sit down and you're, and then
6:45
she goes, so your mother's a schizophrenic. Like
6:48
immediately you start crying to Meg and
6:50
Kelly. They're just good. They know what they're
6:52
doing. They know what they're doing. Let's
6:54
get to the docket. H20s
6:56
banned. The US and China
6:58
trade war has been escalating
7:01
on Monday the White House
7:03
informed Nvidia that they were
7:05
putting an indefinite export restriction
7:07
on NVIDIA's H20 chips to
7:09
China. And so in
7:12
this filing, NVIDIA said it
7:14
expects a $5 .5 billion hit
7:16
to the quarterly earnings stock drop,
7:18
6%. For those of you
7:20
who don't know, H20 is essentially
7:22
the weaker version of the
7:24
H100. It was designed actually to
7:26
comply with these export restrictions.
7:28
on AI chips and allow them,
7:30
NVIDIA, to sell something into
7:33
China. NVIDIA CEO, Jensen Huang, was
7:35
visiting China today. He told
7:37
Chinese state media, quote, the China market is
7:39
very important to us. Yada yada. Saks,
7:41
you're here. I
7:43
think you got some official information
7:45
for us on this. What's
7:48
the story here? Wasn't this supposed
7:50
to be the chip that
7:52
was made for China? In
7:54
a sense, I mean, there is a long history
7:56
to this. Okay. So first of all, just
7:58
to be clear, we're not talking about We're
8:00
talking about export controls. And
8:03
the export controls are designed
8:05
to prevent certain sensitive technologies,
8:07
technologies that could have a
8:09
dual use potential military as
8:11
well as consumer application from
8:13
going to China. And
8:16
this goes all the way
8:18
back to 2019. The first
8:20
Trump administration placed a ban
8:22
on extreme ultraviolet photography equipment
8:24
going to China. This
8:26
is the key technology in the
8:28
printing of transistors on the silicon
8:31
wafer in the semiconductor manufacturing process. And
8:33
there's only one company in the world
8:35
that makes these machines that cost like 200
8:37
million dollars is called ASML. It's a
8:39
company in the Netherlands. In any
8:41
event, the first term of administration prevented
8:44
these machines from going to China, which
8:46
I think in hindsight was a really
8:48
far sighted decision. Because if
8:50
it weren't for that, China
8:52
might today be dominating global
8:54
manufacturing of semiconductors and their
8:56
inability to get that sort
8:58
of lithography equipment, I think,
9:00
definitely put a dent in
9:02
their plans. Subsequent to
9:04
that, in 2022, the Biden administration
9:06
started adding leading edge chips to
9:08
the expert control list, like you
9:10
said, the H100. NVIDIA then
9:12
designed a new chip that was
9:15
basically a version of the H100, but
9:17
they reduced the amount of flops
9:19
or computational power. just below the thresholds
9:21
they continue selling to China. That
9:23
was called the H800. The
9:25
Biden administration then added the H800 to the
9:27
expert control list in 2023. So
9:30
NVIDIA developed the H20, which
9:32
again is kind of like
9:35
a nerf version of the
9:37
H100. This has less computational
9:39
power. I
9:41
think the issue is that FLOPs isn't
9:43
the only criteria by which you
9:45
can measure the power of a chip.
9:47
There's also now memory bandwidth. And
9:50
in the new paradigm of
9:52
reinforcement learning and test time compute,
9:54
memory bandwidth actually matters more
9:56
than the amount of flops. And
9:58
if you look at the memory bandwidth on
10:00
the H20, it actually has 20 % more memory
10:02
bandwidth than the H100. So I
10:05
think there's a view that this chip
10:07
is just frankly too good. And the
10:09
response I'd have to people who don't
10:11
think we should be restricting this is,
10:13
Are you against expert controls in general
10:15
or you just think that we're drawing
10:17
the line in the wrong place here? Because,
10:20
you know, I've heard folks like our friends
10:22
like Bill Gurley and so forth say that. Yeah,
10:24
it's about to pull. That we're making a
10:26
mistake. But I think the question for those people
10:28
is, would you sell them everything? I mean,
10:30
if China wanted to buy the latest NVIDIA chip,
10:32
the GB200, would you sell that to them?
10:34
Would you sell a million of those? Would you
10:36
sell them five million if they're willing to
10:38
pay a premium? It seems to
10:40
me that at some point you have to
10:42
say, that some technologies are just too
10:44
sensitive to be sold to China. And so
10:46
then the question is, are you drawing
10:48
the line in the right place? Let me
10:51
bring Freberg in on that. Freberg, friends
10:53
of the pod like Gavin Baker, said these
10:55
tariffs and these type of bans are
10:57
going to essentially guarantee that America will lose
10:59
AI because, and Gurley as well has
11:01
this position, that we're now going to make
11:03
China force them to make their own
11:05
chips. Now, necessity will be
11:07
the mother invention, and it's going to
11:09
escalate, and we'd be better off
11:11
just selling them. these instead of the
11:13
latest ones. What's your take on
11:15
that, that this will be the inspiration
11:17
for them to build their own
11:19
Nvidia? It's an important question. Last
11:21
year, China announced
11:24
and began a $37
11:26
billion investment in
11:28
developing their own 3
11:30
-nanometer chip technology. So
11:32
the EUV lithography systems
11:35
that SAX is referencing, require
11:38
these wavelengths of light at about 13
11:40
and a half nanometer, which is, you
11:43
know, the previous technology was like 200
11:45
plus nanometer. So it's very, very small
11:47
wavelengths of light that you have to
11:49
be able to manipulate in a very
11:51
kind of discrete way to print circuits
11:53
that are just three nanometer scale. And
11:55
so it turns out that last year,
11:58
China made a claim that this investment
12:00
they had made was starting to pay
12:02
off and they had developed their own
12:04
EUV system. And they're
12:06
big semiconductor companies called the
12:08
Semiconductor Manufacturing International Corporation,
12:10
or SMIC in China. They
12:13
launched a chip, a seven nanometer
12:15
chip with Huawei in their Mate
12:18
60 Pro, which is sort of
12:20
like their iPhone competitor in China.
12:22
And so they're proclaiming that they've already got
12:24
this EUV technology from what I understand
12:26
in sacks would know better than I. It
12:28
sounds like there was a lot of reverse
12:30
engineering and work around. of
12:32
existing technology in order to deliver
12:34
that system. But they
12:37
may now already be investing in and
12:39
developing their own system. So,
12:41
J .Cal, I think they're doing it either way.
12:43
I think that they're going to invest and
12:45
build their own EUV and chip manufacturing capacity either
12:47
way. And the question is, does this slow
12:49
them down or limit their ability on the application
12:51
or the AI layer to kind of be
12:53
held back for some period of time? it accelerates
12:55
because they have no choice but to accelerate
12:58
their commitment to it. Tim,
13:00
you've been talking about these EUV
13:02
technologies in the 200 nanometer. It's
13:04
my entire space. It's my entire
13:06
special. It's a little crazy that
13:08
you'd rip me off like this. My
13:10
entire special is about
13:12
the lithograph. And that's
13:15
the hour that I
13:17
do. You know, I'm of
13:19
the mind if you give a man
13:21
a chip, he makes one semiconductor or
13:23
a few. But if you teach a
13:25
man to make a chip, he makes
13:27
multiple semiconductors and invades Taiwan. So
13:29
that's where I am with this, you know? I
13:33
think we should keep them dependent.
13:35
Keep selling it to them. Keep
13:37
selling it to them. Treat it
13:39
like purpose. understand how this works.
13:42
If somebody becomes addicted to the good stuff,
13:44
then they come back. You don't want
13:46
to give them too much. And you hide
13:48
a little, you backdoor the technology with
13:50
a little surveillance and stuff to have some
13:52
fun. Have some fun. You know, that's
13:54
been done before. Absolutely. Sure, back
13:56
doors all the time. door technology, a
13:58
little surveillance capability, you slip it in
14:01
there. Yeah. Chamath, what's your
14:03
thoughts coming around the horn here? You
14:05
were sort of talking about, I
14:07
think, publicly, obviously, you've got
14:10
GROC and so you're in the
14:12
space with chips. Does this
14:14
net -net end of the day
14:16
slow them down or slow them
14:18
down short term, speed them up
14:20
long term? I think that the
14:22
technology that they need is extremely
14:24
non -trivial, and I do think that
14:26
it actually slows them down quite
14:28
a bit if they don't have
14:30
access to it. Can
14:32
I just take a step back and up -level
14:34
this? I think it was in 2017, the
14:37
State Council of China published
14:39
this plan, and they were incredibly
14:41
transparent and honest. They said,
14:43
this plan is for China to
14:46
become a global leader in
14:48
AI by 2030. And
14:50
it said, so this is in 2017.
14:52
And they said, by 2020, we need
14:54
to have made iconic advances. By 2025,
14:57
we should be a major engine of the industry.
14:59
And by 2030, they should
15:01
occupy the commanding heights, they
15:04
said, in AI tech. OK.
15:06
So why is that important? To
15:09
be honest with you, I think the real problem
15:11
that we have is that Nvidia is not doing what
15:13
is in the best interests of the United States. Oh,
15:16
David mentioned this. When the
15:18
US banned the sale of
15:20
the top end GPUs, the
15:22
A100 and the H100, they
15:24
quickly introduced the A800 and
15:26
H800. What does that mean?
15:28
Well, all it was was just a chip that
15:30
was basically the same. It's
15:33
slightly reduced the data transfer speed so
15:35
that it went under the export control
15:37
threshold, but it was still
15:39
really usable. Then late last
15:41
year, they introduced this thing called this
15:43
H20 that was explicitly designed for
15:45
China and to be compliant with US
15:47
rules at the time, which again
15:49
gives these guys substantial performance. Okay, so
15:52
what do you have? You
15:54
have a 2017 plan that they've been executing
15:56
against, which is to say, we want to
15:58
dominate this space. And you
16:00
have an American company that has been
16:02
working around the guidelines at every turn
16:04
to try to land silicon into the
16:06
hands of China. So then you would
16:08
say, well, maybe there's not that much
16:10
going into China. Nick, can you just
16:12
throw up the chart that I sent
16:14
you about Nvidia's revenue composition? So
16:17
let's just call a spade
16:19
a spade, guys. I think we
16:21
can all do the math.
16:23
About 47 % of all of
16:25
Nvidia's revenue goes to China and
16:28
Chinese related countries. And
16:30
I think when you peel
16:32
back this onion, I think
16:34
what you will find is
16:36
a whole raft of companies that
16:38
were stood up to buy
16:40
these Nvidia GPUs to essentially act
16:42
as a way station for
16:44
China. And I think that is
16:46
the big problem, because it
16:48
doesn't mean that it was just
16:50
these chips that David and
16:52
his colleagues put on an export
16:54
control list. It was every
16:56
kind of chip. And now it
16:58
explains, every single time we
17:00
have an advance in the United States, how
17:03
is it that Alibaba shows up
17:05
with something incredible, DeepSeek shows
17:07
up with something better. At
17:09
every turn and at every step of
17:11
AI, they are at the same rate
17:13
or one step ahead. And I suspect
17:15
it's because that these chips are being
17:17
used in very sophisticated ways behind the scenes.
17:19
And I think that's the issue that
17:22
we need to address. So just to be
17:24
clear, the Insight
17:26
you have here the prediction is people are
17:28
selling these to Taiwan. They're selling them in
17:30
Singapore. I think it's more Hong Kong I
17:32
think it's a group that are zipping them
17:34
over to China mainland or letting them use
17:36
them I don't know if you saw but
17:39
I believe there was a report that there
17:41
was a couple Singaporeans that were arrested for
17:43
actually trying to bring the chips into China
17:45
I don't think it's necessarily that I think
17:47
what happens is you have some entity that
17:49
springs up You know ACME corporation ACME corp.com.
17:51
They show up in Bhutan or Cambodia or
17:53
Vietnam or Singapore And they
17:56
provide a PO, a purchase order to
17:58
NVIDIA, $300, $500,
18:00
$800 million. What
18:02
do you think NVIDIA is going to do? They're going
18:04
to think, well, this is a legitimate Singaporean entity. I'm
18:06
going to sell them the chips, whatever they want. It
18:08
checks all the boxes and
18:10
they look away. And
18:13
what we need to now figure
18:15
out is what happens once those chips
18:17
get delivered. It is the
18:19
only explanation for this. You don't
18:22
have this requirement for this number
18:24
of GPUs for those end markets.
18:26
There is only one end market.
18:28
That's an explosive allegation. Saks,
18:31
what do you think of
18:33
this theory more broadly? I think
18:35
it is a fact that
18:37
there have been both legal and
18:40
illegal attempts to evade the
18:42
US export controls. That
18:44
is true. And there's a number
18:46
of companies that have done
18:48
it. For example, last year, there
18:50
was a case where TSMC
18:52
was discovered to have produced something
18:54
like 3 million chips that
18:56
went into the Huawei Ascend 910C
18:58
chips. I think there's like
19:00
3 million dies or something that
19:02
went into the Huawei Ascend
19:04
chips. And I think they're being
19:06
fined for that. And again,
19:08
this is all public information. Now,
19:11
they claimed that they thought it
19:13
was for a company called, I
19:15
think, SoftCo. It's basically a Bitcoin
19:17
like ASICS company. But nonetheless, this
19:19
did happen. So there have been
19:21
attempts to set up shell companies
19:23
to circumvent the export controls, and
19:25
it is a very big problem.
19:27
Tim, what do you think more
19:30
broadly about what Trump is doing
19:32
with this trade war in China?
19:34
Any takes on China, Taiwan, and
19:36
just how Americans should look at,
19:38
hey, maybe we have to buy
19:40
some more high -quality products. Maybe
19:42
we don't get things on Timu
19:44
as cheap with these $850 exemptions,
19:46
et cetera. I think roughly Trump's
19:48
instincts are correct. I think the
19:50
way that the tariffs rolled out
19:52
seemed to be incredibly chaotic. I
19:54
think that's a huge problem with
19:56
a lot of what the Trump
19:58
administration does. They seem to
20:00
have the correct instincts, but they
20:03
have like a very sloppy rollout, right?
20:05
Like everything's a hard launch. Everything's
20:07
incredibly... I don't know that things are
20:09
messaged the right way. The whole
20:11
doge thing is... little bit of a
20:13
fiasco because the messaging seemed off
20:15
like nobody was out really talking about
20:18
what they were doing and why
20:20
they were doing it. You
20:23
know, I don't know how well this
20:25
works. You know, I mean, you have a
20:27
very integrated global economy. You guys know
20:29
more about that than I do. Are
20:31
you able to unwind that? And if
20:33
you do, you have to unwind it in
20:35
certain areas and certain areas you're going
20:37
to have to allow to
20:39
probably remain relatively stable and
20:41
consistent, right? I mean, if
20:44
you listen to Ray Dalio, he
20:46
talks about like a disaster coming with
20:48
monetary policy, right? The whole unwinding
20:50
of these economic and political structures kind
20:52
of happening at once. I
20:55
don't know. I think Americans do
20:57
over -consume a lot of crap. I
21:00
think cheap goods aren't
21:02
necessarily the highest organizing
21:05
principle of a life.
21:07
I think people have been
21:10
sold the idea that
21:12
cheap goods are more important
21:14
than having a stable
21:16
functioning job and family. I
21:18
think the gig economy has
21:20
been sold to Americans as a
21:22
way to offer them freedom
21:25
and really in chaos at the
21:27
expense of the stability that
21:29
used to come with a job
21:31
with benefits that you stayed
21:33
in for. But
21:35
the other component to that is,
21:37
you know, we have
21:39
to make sure that, like, you know,
21:41
we don't have skyrocketing prices that completely
21:43
decimate people either. So I think you
21:45
need to find a balance. I want
21:47
to see my friends work in factories. I
21:50
want them to get hurt. I want
21:52
to release the safety standards. I
21:54
want child labor. Children are
21:56
terrorists, many of them. They
21:59
start fights in malls. They have
22:01
flash mobs. They run around Chicago.
22:03
trying to kill people that are just
22:06
trying to have shellfish showers on
22:08
the river. So yes, children
22:10
should work. My friend should
22:12
work in a plastics factory. Door
22:15
dash is a horrible job. You
22:18
lose a finger at a factory. It's
22:20
a story. Delivering burritos is
22:22
a hell. Driving Uber,
22:24
all these horrible degrading things we make
22:26
people do. And then tell them
22:28
it's great. And then we look,
22:30
you know, you should destigmatize. being an
22:32
electrician, a plumber, a contractor,
22:34
all these things that when I was
22:37
told, you know, when I was growing up,
22:39
they'd point to a guy doing construction and go,
22:41
you're going to do that if you don't do your
22:43
homework. And then the people that did their homework
22:45
are all, you know, bankrupt. And that construction guy, you
22:48
know, is killing, is killing, is doing pretty
22:50
well. And so what he went to January six,
22:52
he went there peacefully. But the
22:54
whole thing is like, I think
22:56
you need to figure out, you
22:59
know, how to kind of
23:01
reintroduce the idea that this
23:03
gig economy, where people serve
23:05
from one unfulfilling nightmare to
23:07
the next, should
23:09
be thought. Yes, better
23:11
to be in a factory, losing
23:14
a finger in the field. In
23:17
David's estimation, when
23:19
you're talking about these companies that
23:21
are set up to get these chips
23:23
that evade export controls, you
23:25
think is that the Chinese government
23:27
doing that? Is that an intelligence agency
23:29
doing that? Who would be setting
23:31
those companies up? Is it people that
23:33
are interested purely in profit and
23:35
that are then selling those chips? That's
23:37
super interesting. Well,
23:40
I think you have to ask the
23:42
question, Qui Bono. I mean, who benefits?
23:44
Right. think clearly the shell companies, the
23:46
front companies are set up by either
23:48
the Chinese government or entities in China
23:50
to evade the export controls because ultimately
23:52
they want the chips. However, I think
23:54
there is also a problem that Lenin
23:57
described as the the capitalist will
23:59
sell us the rope with which to
24:01
hang themselves. And I do
24:03
think there are a lot of Western companies
24:05
that will look the other way or turn
24:07
to blind eye and just haven't been enforcing
24:09
the rules as religiously as they should because
24:11
it's profitable not to. And this is where
24:14
I do think that the US government has
24:16
to be pretty tough. I mean, if we're
24:18
going to have expert controls in the first
24:20
place, I know there's some people who don't
24:22
think we should have them, but I do.
24:24
I mean, I don't think we should let. China
24:26
have access to our leading edge
24:28
AI technology, we have to make sure
24:30
that the export controls are effective. And
24:33
that means there has to be
24:35
some cracking down in order to make
24:37
that happen. Part of the
24:39
crackdown is we have to define
24:41
the boundary lines in a more
24:44
effective way with fewer loopholes so
24:46
that companies can't legally take advantage of
24:48
those loopholes, but also we're going
24:50
to need more monitoring, more inspection
24:52
and more enforcement. This
24:54
is one of the few areas of the government that
24:56
actually think needs more resources. I think
24:59
that Elon and Doge have identified many areas
25:01
of the government that are massively overstaffed. But
25:03
this is one area, there's
25:05
an agency inside the Department of
25:07
Commerce called BIS that actually
25:09
has to do all of this
25:11
monitoring and inspections and enforcement.
25:13
And I actually think they're understaffed
25:15
relative to the importance of
25:17
this particular task. Let's have a
25:19
thought starter for a second,
25:22
guys. Do you guys think that
25:24
if 47 % of all of
25:26
the AI capability and horsepower
25:28
is being shipped to three Asian
25:30
countries. Where
25:32
do you think the apps
25:34
that require that amount of
25:36
horsepower live? Is there
25:39
a cursor of Bhutan that we
25:41
did not know? Is
25:43
there a great shopping app in
25:45
Cambodia that's come out of
25:47
nowhere that's AI powered? I
25:49
think the answer is no. So we
25:51
already know what the answer is. The
25:54
question is, this is
25:56
a case where you have
25:58
plausible deniability, right? I
26:00
sell something to a
26:02
Singaporean registered company, plausible
26:05
deniability. What am I supposed to do?
26:07
You can't expect me to audit it. I
26:09
think that's what NVIDIA's answer will be
26:11
to this question. But what is
26:13
the real expectation? Let's flip
26:15
it on its head. Last week,
26:18
China in retaliation for tariffs,
26:21
Constrain the supply of rare earths
26:23
outside of China right leaving China.
26:25
You had certain factory lines that
26:27
just had to stop on a
26:29
dime right so. They're clearly in
26:31
a position to understand their supply
26:33
chain who benefits or who doesn't
26:35
benefit and can be hurt by
26:37
constraining supply and they're able to
26:39
affect that. At a minimum the
26:41
United States should have a mechanism to understand it
26:43
whether they do it or not should be up
26:46
to you know powers that be that are bigger
26:48
than. than the four of us or the five
26:50
of us. But that's my point, which is that
26:52
it is implausible that if you did one or
26:54
two layers of work, you would not find that
26:56
most of this traffic is being used by Chinese
26:58
organizations. That may be okay. And
27:00
that's a decision that the United States government
27:02
should make. But it's something that should be
27:04
disclosed to them somehow. And I think if
27:06
you look at the composition of revenue for
27:08
NVIDIA, it is inconceivable that there's a bunch
27:11
of Asian AI apps that are just crushing
27:13
it so hard. No, no. I mean, it's
27:15
so obvious what's happening there. I think
27:17
we Yeah, I think we don't
27:19
need to guess if Taiwan and Vietnam
27:21
do not have the need for that many
27:23
Domestically they're obviously flipping them to someone
27:25
right. It's a it's a it's a given
27:27
some percentage of those are being resold.
27:29
Hey, uh free bird You were on jeopardy
27:32
free bird went to the next round
27:34
wait This is the outro to that. I
27:36
wanted to get Tim in on the
27:38
Jeopardy thing. You should have done like a
27:40
more broadly accessible topic like ours. No,
27:42
the chips are great. I like the chips.
27:44
Do you like that, Tim? I learned
27:46
something. The plausible deniability is interesting. It's
27:49
like the banks that dealt with Jeffrey Epstein, and I know
27:51
it's a sore topic because he was the fifth man
27:53
on this show and RIP and we miss him. The
27:56
show has never been the same. honest, he would have been phenomenal
27:58
on the show. Let's just say he have been good on the show.
28:01
And he would have been good on the show,
28:03
but no, that was a very interesting topic.
28:05
I've never been on a podcast where topics been
28:08
handled. And I'm going to go on Joe
28:10
Rogan tomorrow and just say everything Chamath just said.
28:12
I'm going to go, I'm going to go,
28:14
what did he say? Can we level this
28:17
up or something? Can we high level this?
28:19
What did he say? Can we up level
28:21
it? That's interesting. I say that at Chili's,
28:23
I go, can we up level this? For
28:25
a minute? Yes, $199 extra if you want
28:27
that. If you want the extra jalapenos, Tim.
28:29
So what's going on? Harvard, are we selling
28:31
that to China? I'm for that. Yes. Well,
28:33
there's been a Donny book, if you will,
28:36
Tim. Yeah. In between Trump and Harvard. too
28:38
smart to buy Harvard. They know
28:40
it's a scam. That's a good point.
28:42
Here we go. I just spoke like
28:44
a true Stanford guy. On March 31st,
28:46
three federal agencies announced they were reviewing
28:48
$9 billion, $9 billion in
28:50
multi -year federal grants and $256 million
28:52
dollars in contracts. I went to
28:54
Harvard, three agencies, Education Health, and
28:57
the GSA. This past
28:59
Friday, April 11th, the group sent a
29:01
letter to Harvard's president and the
29:03
head of Harvard Corporation, laid out a
29:05
series of changes. The White House
29:07
is demanding merit -based hiring and admissions
29:09
staff, admissions students, all that good stuff.
29:12
Cancel all your DEI programs.
29:14
No more die. reform international
29:16
admissions. No more admitting students
29:18
that are, quote, hostile
29:20
to American values, increase
29:22
the different viewpoints on diversity
29:24
across all departments and
29:26
abolish admission practices that served
29:28
as an ideological litmus
29:31
test. Harvard's president, Alan Garber,
29:33
said he would not
29:35
comply. Later that day, the
29:37
White House responded by freezing 2 .2 billion in
29:39
grants, 60 million in contracts. They
29:41
now want to take away
29:43
the White House. the tax -exempt
29:45
status of Harvard, which would
29:47
be absolutely insane. It's
29:49
happened actually once before in
29:52
1970s. Bob Jones University in
29:54
South Carolina was doing outwardly
29:56
racist stuff. And the
29:58
IRS, according to the CNN, is
30:00
looking into this. Your thoughts, Shema.
30:05
Well, it's more than the IRS is
30:07
looking into it. They're thinking of revoking
30:09
their tax -exempt status. Yeah. How
30:11
about I tee this up slightly differently?
30:13
Tim, you brought up something that I think
30:15
is really important, which is what is
30:17
the American dream for all these people that
30:19
are cascading between half jobs and half
30:22
measures? That's right. That's
30:24
a really important question. And
30:26
right now, if you
30:28
look at the top of
30:30
the educational hierarchy, Harvard,
30:33
what have we seen over the last few
30:35
years? They are at the absolute bottom
30:37
of the rankings with respect to free speech.
30:39
They have lost all of these cases
30:41
all the way up to the Supreme Court
30:43
about how they do admissions. Harvard
30:46
doesn't just have a front door. It's got
30:48
a bunch of side doors, got a bunch of
30:50
back doors, and they discriminate. And
30:52
what is the opposite of discrimination?
30:54
It's meritocracy. And I think
30:56
with 20 plus years of
30:58
discrimination, what Harvard did was made
31:00
it fashionable for other schools to
31:03
discriminate. And if you
31:05
compound that for 20 years, It
31:07
doesn't just touch the universities, it starts
31:09
to touch the high schools and the
31:11
middle schools. Where we live at the
31:13
beginning of COVID, we had
31:15
some morons at the board of education
31:17
decide to take away AP calculus and
31:19
AP math because it made people feel
31:21
bad. It's absolutely
31:23
ridiculous. And then we
31:26
pound these kids with ADHD pills.
31:29
And what happens is what you
31:31
described him. So. What
31:33
is the point of fixing Harvard? It's
31:35
really important because the opposite of
31:37
what they do, what they do is
31:39
discriminate, is a meritocracy.
31:41
And we need to make that
31:43
fashionable again. And the biggest reason
31:45
goes back to, again, I'll just
31:47
go back to the chip conversation. The
31:50
Chinese are so well organized. If
31:52
you look at the Chinese and the
31:54
Indians together, those are 2 .5 billion
31:56
people swimming in a meritocratic soup from
31:58
the day they're born. That's the only
32:00
way they climb out. and
32:03
it's eat or be eaten. And
32:05
then when they graduate from an education
32:07
system that is purely meritocratic, you know
32:09
what they do? They enter a workforce
32:11
that's also meritocratic. So it's compounded
32:14
into their psyche that you just have to
32:16
perform. Whereas what we do is
32:18
we do all of these fake things that make
32:20
people feel really bad about themselves. They look at
32:22
other people that think that shouldn't deserve to be
32:24
in places, get places. And
32:26
so we have to turn that tide.
32:28
And so whatever it takes, the most
32:30
severe and extreme measures must be undertaken
32:32
to fix this. That's my point
32:34
of view. Tim, your
32:37
thoughts on Trump wanting to
32:39
take away the nonprofit stance of
32:41
Harvey. I
32:43
went to one of these encampments during
32:45
the protests. I wanted to see it
32:47
for myself to see what was going
32:49
on. There
32:51
was a lot of, you'd see
32:54
a non -binary Asian dressed up like
32:56
a Hamas, and I think that's fun.
32:59
I think it's college. So I
33:01
think that people are going to
33:03
express views that are often, you
33:05
know, probably anti -American. I don't think
33:07
we can, you can't
33:09
shield yourself from that. I don't like
33:11
deporting people that are, you know,
33:13
critical of Israel, for example, unless they've
33:15
committed crimes and you can provide,
33:18
they're providing material support, you know, if
33:20
you can prove they're providing. Do
33:22
process. Do process. Well, you need to
33:24
provide, you know, if they're providing
33:26
material support, to Hamas or something like
33:28
that, that's a different story. But
33:30
if here on a legal resident visa,
33:32
they should be allowed the space
33:34
to express themselves as any other American
33:36
citizen would. Now, that being said, it
33:39
is impossible to look at higher education in
33:41
America right now and not be embarrassed. Truly,
33:44
truly, the word is embarrassment.
33:47
These should be the shining example
33:49
of, as Shamath was saying,
33:51
institutions that prepare people for
33:53
the real world. But what
33:55
they really are, they've all
33:57
been captured in this quasi
33:59
religious cult of insanity, where
34:01
people are elevating different types
34:03
of characteristics outside of intelligence
34:05
and merit as the most
34:07
important things to be considered
34:09
for admission, you know, to
34:12
be given academic achievements and things
34:14
like this. It's kind of embarrassing. And
34:16
I think if these institutions are going
34:18
to follow that path, they're going
34:20
to have to live and die on
34:22
their own. They're not going to be
34:24
able to be taxpayer subsidized and funded.
34:26
They have massive endowments from multi -billionaires
34:28
whose families all go, but like
34:30
Jamal said, they do engage in discrimination. And
34:33
frankly, you know, again, I'm not
34:35
for drawing ideological lines and I'm a
34:38
big free speech guy, but I
34:40
do think that you don't find much
34:42
ideological diversity on any of those
34:44
campuses, certainly not in the faculties at
34:46
all. And it doesn't prepare anybody
34:48
for a world and all the politics
34:51
are very aesthetic. I mean,
34:53
all these people are out there,
34:55
you know, showing off, exhibiting their
34:57
virtue. But at the end of
34:59
the day, they're still getting a very cushy
35:01
internship and a nice job. And,
35:03
you know, they're going to summer and Martha's Vineyard.
35:06
You know, for example, I
35:08
was lucky enough to go to the
35:10
Kennedy compound this summer. I went sailing with
35:12
their family and they're really great kids.
35:14
A lot of the kids there were... the
35:16
figure of the rock. Where are they?
35:18
No, they're on, you know, Hannes, whatever, the
35:20
famous thing. Yes. And I went there
35:22
and a lot of their young, their young
35:24
kids are of case kids are young.
35:26
They went to Harvard and a lot of
35:28
these Harvard kids are all good kids.
35:31
But you know, some of them are very
35:33
interesting, right? Cause they, they said to
35:35
me, they said, you own a house in
35:37
the Hamptons. I said, yeah, they go,
35:39
do you ever go out there in the
35:41
winter? I go, yeah, sometimes I do.
35:43
It's quiet and nice. You can write, you
35:45
can work on stuff. They go, yeah,
35:47
well, you know, they go, it's kind of
35:49
depressing to come to the Cape in
35:51
the winter. Cause all these people here are
35:53
on drugs. And it's like, yeah, cause
35:55
you shipped their jobs away. So it's just,
35:57
it's stunning. And these are Harvard kids.
35:59
They're very smart kids. But you have these
36:01
chasms where you would think it would
36:04
be completely obvious to people at this amazing
36:06
academic institution that, yeah, of course, the
36:08
people are on drugs. They're embracing pathological behavior.
36:10
They don't have a future. But these
36:12
schools have become these really insular bubbles where
36:14
these people have these really well -meaning aesthetic
36:16
politics, which says, we don't care about
36:18
your economic circumstances. Here's a trans Batman. And
36:20
I don't think that that that seems
36:22
to be the ethos of higher education in
36:24
America right now and it's it's it's
36:26
very hypocritical and I think it's why the
36:28
Democratic Party no longer connects because they're
36:30
too closely associated with like that type of
36:32
you know that type of a lead
36:34
I identity Politics yeah freeberg what sure that
36:36
should the IRS revoke or threaten to
36:39
revoke here? their nonprofit
36:41
status. Is that a
36:43
fair technique here because
36:45
they won't acquiesce and
36:47
do exactly as instructed? And
36:50
what do you think is going to happen here?
36:52
Will this possibly result in them losing their IRS status?
36:57
Harvard's endowment is
36:59
$53 .2 billion.
37:02
You may make
37:04
7 % return. They're
37:06
making $4 billion a year
37:08
in income generated. from those
37:11
investments in that endowment. I
37:13
think there's a couple of
37:15
two really important questions. One is,
37:17
should the role of the
37:19
federal government be to give out
37:21
money equally to institutions? Or
37:24
should the role be to give money to the
37:26
institutions that are going to provide the highest ROI for
37:28
America? Or is the goal
37:30
to redistribute wealth? And
37:32
is that the point of
37:34
federal spending and federal
37:36
expenditures? So, you know, you
37:38
could kind of think about Harvard,
37:40
MIT, and a few other institutions
37:43
that have truly great research institutions
37:45
embedded within them as being the
37:47
best ROI for America from a
37:49
grant perspective when you're giving out
37:51
research grants. That's the best
37:53
place because it just like any other
37:55
great technology company, it accumulates capital
37:57
because it accumulates talent. And that has
37:59
a network effect. And now you've
38:01
got a few institutions that have a
38:03
monopoly on high quality talent. And
38:05
as a result, it's the best ROI
38:07
for America. Is that what
38:09
the federal government is investing in? Or
38:12
should the federal government be trying
38:14
to support universities all over the place
38:16
that are more in need, particularly
38:18
a university that has 53 billion of
38:20
capital? Do they really need the
38:22
federal funds? So then the next question
38:24
I think is like, what is
38:26
the limit on the government's ability to
38:28
influence whether or not an institution
38:30
gets their capital? Is it statutory? Is
38:32
it mandated by law? Or
38:34
does it become politically motivated,
38:36
socially motivated, et cetera? Because
38:38
in other parts of how we're seeing
38:40
decisions being made, we're saying Chevron doctrine
38:42
was thrown out. And when Chevron doctrine
38:44
gets thrown out, we can't
38:47
rely on the regulatory scrutiny of the administrators
38:49
of the capital. We have to rely
38:51
on the law. And is there a law
38:53
that they're relying on? And I think
38:55
that's the key question is to have the
38:57
administration point to the laws that they
38:59
believe are being violated to kind of make,
39:01
I would say, a strongly defensible argument
39:03
about why they would withhold the capital to
39:05
make sure that they're compliant with the
39:08
law and whatnot and have it not be
39:10
kind of, you know, just we would
39:12
prefer to see you do things differently because
39:14
we think it's socially better. So I
39:16
think those are kind of the two key
39:18
points, whether or not these institutions deserve
39:20
nonprofit status. I don't know why an
39:22
institution that has 53 billion a capital and
39:24
is making probably four or five billion a year.
39:27
shouldn't pay taxes on that income. That
39:30
income is being used in a variety
39:32
of ways to build nice buildings. And
39:34
there's IP that's held by these institutions
39:37
that IP is used to start startups.
39:39
They get equity in the startups. They
39:41
have income streams on their IP. I
39:43
mean, they really do operate like technology
39:45
development centers. So, you
39:47
know, what is the original kind of reason for
39:49
saying that they should be tax exempt? The
39:51
majority of the capital is not being used to
39:53
educate students. The majority of the capital is
39:55
being used to reinvest to make new capital. So
39:58
your position on
40:01
Harvard losing its tax
40:03
exempt status potentially because they will
40:05
not stop their DEI programs or they want
40:07
to, I guess, better stated would be that
40:09
they want to make their own decisions about
40:11
this and not have the federal government make
40:13
this decision. Let's get to the
40:15
nitty gritty of the legal issue here.
40:17
In 1983, there was a case called
40:19
Bob Jones University versus the IRS in
40:21
which the IRS challenged the tax exempt
40:23
status of Bob Jones University because Bob
40:26
Jones had this bizarre
40:28
and reprehensible policy banning interracial
40:31
dating on campus and interracial
40:34
marriage based on a strange
40:36
interpretation of scripture. At least that's what they
40:38
said it was. In any event, Bob
40:41
Jones lost that case and they lost their tax
40:43
exempt status. As far as I know, they
40:45
kept the policy and they continue to operate as
40:47
a private university. But the
40:49
Supreme Court found that
40:51
if you enshrine a racially
40:53
discriminatory policy, in
40:56
violation of the civil rights laws and you
40:58
cannot get tax against status. So that
41:00
was the precedent. Fast forward
41:02
to 2023, we have the
41:04
case students for fair admissions versus Harvard. This
41:06
is the Supreme Court case a few years
41:08
ago that said that affirmative
41:11
action policies that
41:13
use race as a
41:15
factor in admissions are a
41:17
violation of the 14th Amendment's
41:19
protection against racial discrimination. So
41:22
Harvard lost that case. They were
41:24
found to be racially discriminating in
41:26
admissions. Now, what Harvard did
41:28
in the wake of that is
41:30
that they claimed that they
41:32
removed access to information about
41:34
an applicant's race from the
41:36
admissions process so that the
41:39
admissions readers don't know what race of
41:41
student is. This is their claim. But
41:43
at the same time that they did
41:45
that, they updated their application, replacing
41:48
the long form essay that all of
41:50
us filled out decades ago we went
41:52
to school with five shorter questions asking
41:55
how applicants will contribute to a diverse
41:57
student body. It's suspiciously similar
41:59
to these DEI statements where prospective
42:01
professors who are applying for jobs
42:03
at these universities get asked, you
42:06
know, how will you contribute to diversity on
42:08
campus, things like this? And it's
42:10
used as a way to discriminate
42:12
against conservatives or people who just think
42:14
that race or diversity should not
42:16
be a factor in teaching on campus.
42:18
Anyone who answers that question, I
42:20
believe in judging people based on the
42:23
content of their character, not the
42:25
color of their skin, they're going to
42:27
get weeded out, right? I mean,
42:29
or someone who says, well, I'm going
42:31
to contribute to diversity on campus
42:33
by contributing intellectual diversity. Those are the
42:35
types of applicants who get weeded
42:37
out by these DEI statements. And we
42:39
see that in another part of
42:41
what the government is claiming is that
42:44
Harvard is engaged in viewpoint discrimination
42:46
against conservatives. And you can see this
42:48
in polling of the Harvard faculty.
42:50
More than 80 % of surveyed Harvard
42:52
faculty identify as liberal. So my point
42:54
is this, these
42:56
DEI statements have been used in
42:58
faculty hiring to discriminate on the
43:01
base of viewpoint and to use
43:03
race as a factor in hiring. I
43:05
think in a similar way, they've
43:07
now updated their admission application to
43:09
make all the essays about race.
43:12
So I think this idea that
43:14
they're not playing a game here
43:16
and they're not trying to engineer
43:18
the student class around race, it's
43:20
hard to believe, right? I mean,
43:22
these are people who have not
43:24
changed their ideology. They believe what
43:26
they were doing before that 2023
43:28
case was trying to engineer the
43:30
percentages of each student class to
43:32
match the percentages of each race
43:34
in the American population, right? And
43:36
these are people who are doctrinaire
43:38
about that ideology. So the
43:40
idea that they're not still doing it, I
43:42
think, is hard to believe. Now,
43:45
course, of course. So we all know
43:47
what they're doing. And The alternative
43:49
to the administration saying just get rid
43:51
of the is that every year
43:53
to have new litigation. Where will
43:55
be some whistleblower and it'll come out
43:57
that harvard still engaging a racial discrimination.
44:00
And then you know harvard will be found
44:02
guilty like they were in that twenty twenty
44:04
three case and they'll change their policy. And
44:06
the manipulated and play some new game will
44:08
be a new court case will keep going
44:10
back and forth with them or. We
44:12
can just say stop it right
44:15
now stop the non sense actually. abide
44:17
by both the letter and spirit of
44:19
the Supreme Court decision students for fair
44:21
admissions versus Harvard and stop engaging in
44:24
racial discrimination. And this is why I
44:26
think the administration is correct here in
44:28
pressing Harvard on this. Now look, if
44:30
Harvard wants to keep playing these games,
44:32
they can. No one is saying that
44:34
they have to get rid of DEI.
44:36
They just have to give up their
44:39
federal funding the way that Bob Jones
44:41
University did. But the problem is that
44:43
Harvard wants to have his cake and
44:45
eat it too. Right? They want to
44:47
basically keep engaging in racial discrimination through
44:49
these DEI policies, but they want federal
44:51
funding and you can't have both. Do
44:54
you think that these
44:56
universities or universities in
44:58
general that receive federal
45:00
funding have become more
45:02
ideologically, call it liberal,
45:05
I would call it a
45:07
little bit more kind of socialist
45:09
oriented because they're dependent on
45:11
federal funding? Do you see what
45:13
I'm saying? Like, is it the case that
45:15
this Ideology accrues over
45:17
time when you are much more
45:19
dependent on the government. You
45:21
mean there's no market feedback that keeps
45:23
you in check? There's no
45:25
private market. There's nothing that
45:27
ultimately translates into a system
45:30
where you're necessarily needing to
45:32
be competitive for capital, competitive
45:34
for talent, like the accumulation of federal
45:36
dollars over time. makes you say I deserve
45:39
federal dollars and the people that think
45:41
that you deserve federal dollars. You're making a
45:43
really good point and I think you
45:45
could be right. Nick, can you please throw
45:47
up the chart that I sent you,
45:49
which is the amount of research between China
45:51
and America? Okay, first look at this.
45:54
So again, you make these plans
45:56
and you're like, where are we
45:58
going to put the money? Okay,
46:00
China says, guys, we are going
46:02
to learn how to catch up
46:04
to America in terms of spending
46:06
on science. This is gross domestic
46:08
expenditures on science. And what you
46:10
see is China from basically nothing
46:12
in 2001 is now neck and
46:14
neck with the United States spending
46:16
half a trillion dollars a year
46:18
on core fundamental science research. So
46:20
what happens as a byproduct of
46:23
that? Okay, so you spend more
46:25
on the way in. So
46:27
China is listening to the market
46:29
feedback. Freeberg, let's go and explore
46:31
this idea that there is no
46:33
market feedback in America. What are
46:35
the long run implications and you
46:38
see it on this chart, which
46:40
is this is a simple chart
46:42
that says what percentage of all
46:44
of the foundational research Comes from
46:46
the United States versus comes from
46:48
China and what's crazy about this
46:51
chart is right around 2019 China
46:53
past the United States This chart
46:55
by the way only measures research
46:57
that is published in English Okay,
47:00
so if you added in
47:02
the research that China actually publishes
47:04
in Chinese, they would have
47:06
run away with this a decade
47:08
earlier. So then you
47:10
think about, okay, well, what is
47:12
the implication of this? Well, the implication
47:14
is obvious. These guys are
47:16
inventing things. We're playing catch -up. Meanwhile, we're
47:18
bumbling around talking about pronouns. We can't get
47:20
our act together. This is why we
47:22
need to be decisive. What is important here?
47:24
So for NIH grants, This was published
47:26
by the NIH, by the way, a few
47:29
weeks ago on their Twitter account. So
47:31
this is an image they put out. And
47:34
on Feb 15, they're about the
47:36
NIH said, any grants we give to
47:38
universities now. So today, if you're a
47:40
researcher, you're a scientist at a university
47:42
like Harvard, I don't know if
47:44
people realize this. The way you get funding
47:46
for your lab is you will apply for a
47:48
grant. Someone has to give you that capital
47:51
to run your lab. And many
47:53
grants come from the NIH. So
47:55
they go to the NIH, they file
47:57
for a grant. If the grant gets
47:59
approved, they get $3 million, let's say.
48:02
But what happens is that at
48:04
the institution that they run
48:06
that lab at, that institution can
48:08
now bill the government for
48:10
some negotiated percentage of the grant
48:12
amount to cover administrative overhead. So
48:14
at Harvard, you know what the administrative
48:17
overhead was up until Fed 15th? 69%.
48:21
You're saying $69 of every
48:23
hundred go to administration. It's
48:26
an incremental $31. Yeah.
48:28
Well, it's actually an incremental $69.
48:30
So the way it works is on
48:32
top. The lab gets a hundred
48:34
and then Harvard bills the government $69.
48:37
That's insane. That's insane. And
48:39
this is true. And the average is
48:41
around 30 % today across universities and
48:43
other institutions. So there's also this very
48:45
fundamental question that's being asked in science
48:47
right now. which is our university is
48:49
even the right place to be doing
48:51
fundamental scientific research. In the United States,
48:53
there are different models. Most of our
48:55
research is done either at a private
48:57
company, which is a small amount of
48:59
research. And remember, I've
49:01
talked about this a lot. The
49:03
big companies that have a market that's
49:05
telling them you have to have
49:08
a positive return on invested capital, that
49:10
have the scale to invest, have
49:12
the most incredible returns for America, like
49:14
Google. that put out the transformer
49:16
model that launched everything that we see today and
49:18
invested in Waymo for many years and drove
49:20
the self -driving car revolution and all the work
49:23
that was going on at Bell Labs up until
49:25
we said Bell Labs and Monopoly, we broke
49:27
them apart and they got destroyed. And
49:29
so we largely aim to destroy large
49:31
private research institutions in this country because
49:33
we claim that they're monopolistic because of
49:35
the way they source capital, which is
49:37
through activities in the marketplace. So
49:39
the question today that's being asked,
49:41
is should we be doing fundamental
49:43
scientific research at universities given that
49:45
over time, the administrative overhead has
49:47
grown. And they're basically creating administrative
49:49
workloads and employing people without necessarily
49:51
having a market incentive. Can I
49:54
tell you a crazy story? This
49:56
is a story I've never told,
49:58
but a friend of mine is
50:00
an incredibly well -respected banker on
50:02
Wall Street, very senior guy, works
50:04
at one of the big mainline
50:06
banks. And a few
50:08
years ago, this is about 18 months ago, two years
50:10
ago, he had always wanted
50:12
to work in government and they
50:14
tried to get him to join the
50:16
Federal Reserve and it was for
50:18
a role that was very specific and
50:21
narrow. It was to manage a
50:23
very specific part of the interest rate
50:25
mortgage market. It's a really important
50:27
role. It's a little bit in the
50:29
weeds, but it was like his
50:31
dream job. He did his PhD thesis
50:34
on it the whole nine yards,
50:36
whatever kind of thing. So
50:38
he goes through these interviews
50:40
and He sits with Jerome Powell, goes
50:43
through that interview, sits with, I
50:45
think, Leo Brainard, you know, everybody. And
50:48
it was time for the final interview.
50:51
And right before, the person that was
50:53
his kind of like shepherd says
50:55
to him, you really need to play
50:57
up your Indianness, because what we
51:00
really want is somebody who can help
51:02
us tell a diverse story. He
51:04
goes, well, My diversity is that I
51:06
know this market better than literally
51:08
anyone else in the world. Like nobody
51:10
knows this. I know it. I've
51:12
studied it since my PhD. And
51:15
he was so offended. He was like,
51:17
you know what? I'm not going to
51:19
go through with this. And we lost
51:21
them. We meaning the American taxpayer who
51:23
supports all this. If you think of
51:25
that example in all of the different
51:27
places where we have not been hiring
51:29
the right people, you
51:31
get this slowdown in innovation,
51:33
you get a slowdown in research,
51:35
you get a slowdown in
51:37
wealth functioning organizations and institutions, and
51:40
it's like a slow malaise. So
51:42
how do you stop the rot? You
51:44
have to stop it at the top, and
51:47
you have to do something that is
51:49
meaningful. And if
51:51
it requires us
51:53
to at least
51:55
threaten Harvard, and by
51:57
the way, look, let's be honest, it's
51:59
called Harvard Corporation for a reason. Right,
52:01
it's run like a corporation. It is
52:03
an asset manager that may happen to
52:05
have some educational things that they do
52:07
on the side which Increasingly are not
52:09
what we need it to do and
52:11
more importantly It doesn't set the vanguard
52:13
for how everybody wants to copy and
52:15
everybody used to want to copy Harvard
52:17
and now what they're copying are not
52:19
the things that help us so we
52:21
have to find a way of Waking
52:23
them up and saying guys you have
52:26
a responsibility for America And
52:28
maybe this is what it takes. And I hope
52:30
they take the medicine and listen. Well, the Coulson
52:33
brothers told us on a previous episode, they were
52:35
just funding researchers and letting them pick their own
52:37
research to a certain extent. Tim. How
52:39
would you play up your Indianness
52:41
with Jerome Powell? The idea
52:43
of that is the best thing I've
52:45
heard all week. I've asked him. He
52:48
was told to play up his Indianness.
52:50
And he was like, well, what does
52:52
that mean, my Indianness? And they were
52:54
like, well, you know. Talk about your
52:56
love of Indian dance and Indian food.
52:58
And he was like, are you, are
53:00
you, are you kidding me? Like is,
53:02
is this a serious conversation? Jerome Powell
53:04
sitting there and go, we were on
53:07
defense about you. But you showed up
53:09
with this butter chicken. The chicken makni,
53:11
I was gonna bring it up. You
53:13
came in here with Saag Paneer, and
53:15
now we're a sitar. He starts playing
53:17
the sitar in the... And it's like,
53:19
what are you doing? You char masala?
53:21
Who's that guy showing up at a
53:24
rickshaw? It's the chairman of the mortgage
53:26
market. It's absolutely worked out. Hey,
53:28
Tim, if you were in charge of
53:30
this, because we do have some ends with
53:32
the administration, maybe you should be directing
53:34
some of this research. What would me? If
53:36
I wanted to study anything at Harvard,
53:38
it would be Brigitte Macron's gender. But I
53:40
think we do have to focus on
53:42
disease to an extent. But here's
53:44
what I would say to add to
53:46
that conversation. I would say that these
53:48
schools exist for a multitude of reasons.
53:51
But one of them is to create
53:53
a consensus among the wealthiest and obviously
53:55
people that are expected to be the
53:57
most powerful in society and to
53:59
create a consensus about the values that
54:01
are important to America at any
54:03
given time. And I think the
54:05
question should be, why are
54:07
these values so important
54:10
and to whom? I
54:12
don't think this is altruism
54:14
and it's about helping the
54:16
working class or helping minorities
54:18
or helping people get more
54:20
economic justice. It actually
54:23
seems to me quite
54:25
a transparent attempt for certain
54:27
people to keep positions
54:29
of power and certain structures
54:31
to stay in place
54:33
while offering people this idea
54:35
that there's a lot
54:37
of change because there's a
54:39
few ceremonial optical choices
54:41
made where we're putting in
54:43
a female CEO of
54:45
color or someone who's Indian
54:48
but the internal structure
54:50
stays the same. And
54:52
if you just look at a school
54:54
like Harvard and you go, oh, yeah,
54:56
socialist in some respects, but in some
54:58
respects, actually, you know,
55:00
if you challenge the Ukraine war,
55:02
if you challenge aspects of the
55:04
American empire, if you challenge certain,
55:07
look at all the wars, all
55:09
of our wars are being sold
55:11
with social justice. A lot of
55:13
our wars are being sold because, you
55:15
know, if we don't see a national
55:17
security interest in it, we're told that
55:19
Well, people in that country are not
55:21
being treated well. That country has values
55:23
that we don't have in the West.
55:25
And that may be true. But in
55:27
many cases, it's not worth going to
55:29
war over. And most Americans would say
55:31
that. So who exactly
55:33
is benefiting from these
55:36
programs and these values
55:38
being instituted? It isn't
55:40
low income people in
55:42
the inner city. It
55:44
seems to be kind of
55:47
A lot of it's the
55:49
opposite of inclusion. It's the
55:51
opposite of inclusion. the opposite
55:53
of inclusion. What has happened?
55:56
It's the establishment trying to
55:58
preserve itself by shutting out
56:00
certain ideas and certain people
56:02
and, you know, giving very
56:04
ceremonial nods to, you know,
56:07
play up your Indianness, play
56:09
up this, play up that.
56:12
But, you know, it's like when the
56:14
CIA goes and she goes, I'm
56:16
the first female drone pilot. And
56:18
a lot of Americans are
56:20
going, what exactly is our national
56:22
security interest in a drone
56:24
strike in whatever country and do
56:26
we need to be doing
56:28
this? And should the money be
56:30
better spent somewhere else? But
56:32
instead of having that conversation, it's
56:34
always ends up being hijacked.
56:36
So this DEI to me just
56:38
seems like a way for
56:40
a lot of the same establishment
56:42
people to keep their power
56:44
and influence by offering these very
56:46
optical advancements to people that
56:48
May you know pay lip service
56:50
to certain ideas, but when
56:52
it comes down to it, they're
56:54
very loyal to the same
56:56
Power factions that you know have
56:58
always kind of driven the
57:00
narratives in our country completely agreeing
57:02
what happened during comedy to
57:04
you Tim and and your cohort
57:06
during that like peak DEI
57:09
peak cancellation It felt like the
57:11
Overture window was closing pretty
57:13
harshly on you guys. There's a lot
57:15
of attempted cancellations of comedians, people trying
57:17
to secretly record you. You got those
57:19
yonder, I don't know what those are
57:21
called, those bags that you put the
57:23
phones in. What was that moment
57:25
in time like? told by countless executives
57:27
to play up my Indianness, and I tried.
57:30
You tried. But it was just in bad
57:32
taste. Yes. It was in terrible
57:34
taste when I came in and I tried to
57:36
be Indian, and it just wasn't
57:38
good. No, I think here's what it was.
57:40
I started, you know, having more of a career
57:43
in let's say 2016, 2017, 2018, and then
57:45
we were kind of on this path where you'd
57:47
go have a meeting in Los Angeles with
57:49
people about doing a show or whatever, and they
57:51
would start, all of these words and verbiage
57:53
would creep in. They go, we're really interested in
57:55
marginalized voices, elevating voices that
57:57
haven't been heard. We're interested in
58:00
empowering, and these are LA executives, they're
58:02
monsters, they care nothing. about anything
58:04
and that's where they're good at their
58:06
job, right? The only reason you
58:08
can be good at your job as
58:10
an executive in the entertainment business
58:12
is to really not look at human
58:15
beings as humans. You have to
58:17
look at them as objects. That's
58:19
what you do. Manipulate pawns on the chessboard.
58:21
It's what it is. You know what I
58:23
mean? If I called my agent today and
58:25
said I'm really tired, doing everything I'm doing,
58:27
he'd say, have you tried drugs? Like, they...
58:29
Right, this would be a... I was wondering
58:31
about that because you have such high energy.
58:33
I don't know why you're not embracing the
58:35
cocaine speed. I don't mean it. I don't
58:37
mean it. Yeah, but if I do, and
58:39
the way, if I do, they'll provide it
58:41
to me. Here's the deal. The way that
58:43
town works is you have a bunch of
58:45
people that believe in nothing and they can't.
58:48
They can't and be effective. They have to
58:50
go whichever way the wind is blowing. So
58:52
when you have these people pulling up in
58:54
portions, with their houses
58:56
in Malibu and they then
58:58
have a sudden interest
59:00
in empowering people. These people
59:02
were throwing women off
59:05
into the Santa Monica Canyon
59:07
for years. So it
59:09
was this weird time where
59:11
you had the worst people in
59:13
the world trying to convince
59:15
you that they had an interest
59:17
in marginalized voices because they
59:19
thought there was money there. Well,
59:21
guess what? It turns out
59:23
Americans don't really like to be
59:25
patronized and they were never
59:27
making TV that minorities wanted to
59:29
watch or making TV that
59:31
guilty white liberals wanted to watch
59:33
and it didn't make any
59:35
money. Nobody really liked it. A
59:37
lot of it kind of
59:39
faded away. And as soon as
59:41
it stopped being profitable, all
59:43
the executives in Hollywood that supposedly
59:45
cared so much about the
59:47
marginalized voices rediscovered the profit motive.
59:49
They rediscovered the idea that
59:51
they had to make entertaining stuff.
59:53
They rediscovered viewership. They rediscovered
59:55
numbers. They rediscovered all these business
59:57
fundamentals that they had ignored
59:59
because they thought there was going
1:00:01
to be a pot of
1:00:03
gold at the end of all
1:00:05
this elevating and empowering. But
1:00:07
there wasn't because it was rejected
1:00:09
largely by people. They didn't
1:00:11
want to watch it. They were
1:00:13
canceling all of you guys.
1:00:15
They were canceling. Well,
1:00:18
they were trying. They were
1:00:20
trying to. to. They were trying, didn't
1:00:22
work because people at the end of
1:00:24
the day realized that people are flawed,
1:00:26
fallible, and human. And that's what makes
1:00:28
them entertaining. You don't want a perfect
1:00:30
person doing anything because that person is
1:00:33
not going to be terribly interesting. You
1:00:35
want someone who has flaws and has
1:00:37
problems, obviously, within reason. You
1:00:39
know, so I think that. Tim,
1:00:41
can I ask you a
1:00:43
question? Let's say let's say that
1:00:45
you are I support Harvey
1:00:47
Weinstein. Go on. I'm sorry. I
1:00:49
didn't know if that was
1:00:51
No, let's say that you are
1:00:53
in charge of education in
1:00:55
America. Yes What would you do?
1:00:57
Where would you start? What
1:00:59
would you if I was in
1:01:01
charge of education America number
1:01:03
one? I would I would try
1:01:05
to Assert the idea that
1:01:07
Higher education itself needs to be
1:01:09
for a purpose and
1:01:11
that there needs to be more
1:01:13
of a purpose driven from
1:01:15
middle school through high school, we
1:01:17
need to start getting kids
1:01:19
to think rationally about their skill
1:01:21
set and their ability. And
1:01:24
I don't think it's a
1:01:26
good idea for these kids to
1:01:28
take out hundreds of thousands
1:01:30
of dollars worth of loans to
1:01:32
go away for four years,
1:01:35
not have a solid plan and
1:01:37
not execute and then graduate
1:01:39
mired in debt without
1:01:41
really a pathway to paying any of
1:01:43
it back and spending their 20s and
1:01:45
maybe a good part of their 30s
1:01:47
incapable of owning a home, incapable of
1:01:49
owning anything with no real investments. So
1:01:51
I think this idea that like you
1:01:53
should follow your dream, which is this
1:01:55
toxic American idea that I don't subscribe
1:01:57
to. I think people have nature as
1:01:59
they have skillsets and they actually have
1:02:01
to do something within the realm of
1:02:03
that and it requires being honest with children,
1:02:06
which no one wants to do. And
1:02:09
I would try to re -engineer education
1:02:11
to be a more practical place
1:02:13
where you would apply some of the
1:02:15
skills that you actually had. I'm
1:02:18
not saying people shouldn't be able to
1:02:20
experiment or have freedom, but I
1:02:22
do think that we've told a lie
1:02:24
to people, which is that they
1:02:26
can be anything they want to be
1:02:28
and do anything they want to
1:02:30
do. And by the way, and here's
1:02:32
a bunch of loans to do
1:02:35
it. Here's hundreds of thousands of dollars
1:02:37
worth of debt. So now you
1:02:39
can go into debt. without any plan
1:02:41
or any logical sense of what
1:02:43
you want to do. I think we
1:02:45
should start putting people into a
1:02:47
more realistic mindset in high school about
1:02:49
what needs to happen. Otherwise, they're
1:02:52
taken advantage of and abused by these
1:02:54
systems of higher education where they
1:02:56
graduate mired in debt and without any
1:02:58
type of standing in society. Oh,
1:03:01
my God. I want to add
1:03:03
Jamal. Go ahead, Freya Bergen. Then
1:03:05
I got a breaking news story.
1:03:07
I want to just address this
1:03:09
because I think it's, there's a
1:03:12
moment here that I think will
1:03:14
define a very different future for
1:03:16
education, which is kind of a
1:03:18
movement away from the current model
1:03:20
of a school. AI is
1:03:23
such a profound tool. The
1:03:25
ability for AI to get to
1:03:27
know your personality and just like teach
1:03:29
my kids the way they want
1:03:31
to be taught through conversation, through engagement,
1:03:33
through dialogue. knowing that some
1:03:35
kids want to ask questions and some kids
1:03:37
want to just be told stuff. Some kids
1:03:39
work at one pace, other kids work at
1:03:41
another pace. And I know this idea of
1:03:43
personalized education using computing has been around now
1:03:45
for decades. But we really are
1:03:47
in this moment where the idea of
1:03:50
spending, you know, your first 18 years
1:03:52
of life in a classroom where you're
1:03:54
being told stuff that is quote the
1:03:56
truth versus learning how to engage with
1:03:58
the world, ask questions, your
1:04:00
world. I find and identify things that are
1:04:02
interesting to you. have it delivered to you
1:04:04
in a very personalized, meaningful, rich way that
1:04:06
also makes you excited about certain things and
1:04:08
helps usher you on to the next phase
1:04:11
of your life of what do you want
1:04:13
to do with this and get kids out
1:04:15
of this idea that you've got to go
1:04:17
get the degree in order to get the
1:04:19
job. And then I think that the workplace
1:04:21
will adjust to that. I forgot who it
1:04:23
is, whether it was Palantir or someone just
1:04:25
started doing a program where they're like skip
1:04:27
college, come and do your basically your apprenticeship
1:04:29
here. So instead of going to college, you'll,
1:04:32
you'll, it's paid, you'll continue your education
1:04:34
here. You'll work on projects,
1:04:36
you'll make money and you'll continue to
1:04:38
have your development be done while you're
1:04:40
learning a valuable skill. So I do
1:04:42
think like as AI kind of takes
1:04:44
over education, I do expect that the
1:04:46
workplace will change Tim and we will
1:04:48
start to see more of this integration
1:04:51
between education and workplace enabled by this
1:04:53
AI driven kind of, you know, development
1:04:55
system. Which is which is going to
1:04:57
be radically different than what we have
1:04:59
today you with this a item you
1:05:01
like a comedians to the game I
1:05:03
don't I don't with it. No, I'm
1:05:05
a little skeptical of the tech people
1:05:07
I talk about on my show of
1:05:09
course not you guys but the other
1:05:11
ones I Think it's great Palantir goes
1:05:13
skip college come get involved in advanced
1:05:15
weapons technology But
1:05:26
I like using my brain at the moment,
1:05:28
but if it starts to fail, I imagine it
1:05:30
will. I will use A. I know people
1:05:32
that do use A. I might produce or might
1:05:34
use A. I don't know. You probably won't
1:05:36
tell me. But I do think that...
1:05:38
But have you used it to learn Tim? Have you
1:05:40
used it? Have you ever done any of the chat apps
1:05:42
where you can talk to it and like, hey, you
1:05:44
want to learn it or get smart on something or get
1:05:46
caught up on something? You can literally just ask questions
1:05:48
and have a conversation with it. We did
1:05:50
it on the show. We had
1:05:52
an AI bot do a deliver
1:05:54
rant in the style of me.
1:05:56
It got pretty close, not good
1:05:58
enough yet, but it was pretty
1:06:00
close and pretty interesting to see
1:06:02
how advanced it is right now
1:06:05
and then how advanced it's going
1:06:07
to be. You know,
1:06:09
I worry a little bit about what
1:06:11
you're going to do with all of
1:06:13
these people. once AI starts
1:06:15
taking a lot of these
1:06:17
jobs. The
1:06:19
cashiers, the Uber drivers,
1:06:22
door dashers, all these jobs could go like
1:06:24
you said. Five years ago, I was
1:06:26
a tour guide on a double, not five
1:06:28
years ago, but seven or eight years
1:06:30
ago, I was a tour guide on a
1:06:32
double -decker bus in New York City while
1:06:34
I was learning how to be a
1:06:36
comedian and I was showing people the Empire
1:06:38
State Building and like all the 9 -11
1:06:40
Memorial, whatever, and these are the
1:06:42
types of jobs I was making $13
1:06:44
an hour and I was obviously, you
1:06:47
know, it wasn't well paid, it wasn't an
1:06:49
amazing job and it offered me the freedom to
1:06:51
get good at something else. But I was
1:06:53
taking a lot of risk to do it and
1:06:55
I tolerated that level of risk because I
1:06:57
believed what I was doing was the right thing,
1:06:59
the right course of action. But it's jobs
1:07:01
like that that allow some of the most interesting,
1:07:04
you know, like weird
1:07:06
lives that people should
1:07:08
be able to live If
1:07:10
they want to, I
1:07:13
don't think everybody may want
1:07:15
or need to have a full
1:07:17
-time job. There are people that
1:07:19
have retired and go, I'd
1:07:21
like to be a tour guide, or
1:07:23
I'd like to work at a museum a
1:07:25
few days a week. being
1:07:28
on the double -decker bus, you know, were you
1:07:30
able to put one -liners in there? I was
1:07:33
able to do all kinds of stuff like
1:07:35
that. To me, it's like those jobs, right? Yes.
1:07:37
Some of those, I don't think the entire
1:07:39
economy should be the gig economy, but I do
1:07:41
think some of those jobs are going to
1:07:43
be eliminated by AI or the jobs that allow
1:07:45
people to get good at other things while
1:07:47
they're doing them. So people that
1:07:49
are in entertainment and music and stuff like
1:07:51
that, we want them to be able
1:07:53
to support themselves while they enrich us culturally
1:07:56
in other ways. Crazy breaking
1:07:58
news story right now. Um, sorry, sacks. I
1:08:00
didn't mean to have this, uh, blindside you
1:08:02
here, but, uh, and I know, you know,
1:08:04
you were at the administration, you don't speak
1:08:06
for the administration necessarily on this issue, but,
1:08:08
uh, looks like the federal reserve has a
1:08:10
new chairman. It's just breaking news here. So
1:08:12
racist. Um, it says hot off
1:08:14
the mark. Trump is named Shamath as the federal
1:08:16
reserve. I think all of these fundraisers worked out
1:08:18
for you, but, uh, there is a note. They
1:08:20
asked Shamath to be more Sri Lankan. So if
1:08:22
you could, to the extent you could be more
1:08:25
Sri Lankan. Chumas, is he
1:08:27
really Sri Lankan? I read
1:08:29
a great book about the
1:08:31
Tamil Tigers many years ago.
1:08:33
Do you remember them? Yes,
1:08:35
they invented suicide bombing. They
1:08:37
did. Listen be proud be
1:08:39
proud of stuff That was
1:08:41
the ethnic minority that was
1:08:44
fighting for a homeland I
1:08:46
was part of the ethnic
1:08:48
majority You were you were
1:08:50
the one trying to avoid
1:08:52
the suicide mess. No, my
1:08:54
dad was the one that
1:08:56
spoke out against the war
1:08:58
That's why we we had
1:09:01
to skedaddle and claim refugee
1:09:03
potato potato. I support both
1:09:05
I'm the only person with
1:09:07
the moral courage to say
1:09:09
I support Israel and Hamas
1:09:11
and Russia and Ukraine. You
1:09:13
can just want to see a good game.
1:09:16
You can want to see a good game. You
1:09:18
don't have to take a side. overtime if
1:09:20
there's a lead change. You like a
1:09:22
lead change. It really depends in Beverly
1:09:24
Hills who I'm having lunch with and what
1:09:26
type of Middle Eastern they are because
1:09:28
I can go either way on that. And
1:09:30
I think it's important. You don't
1:09:32
want be too rigid in this economy.
1:09:34
You need to be able to move
1:09:36
into things And I will read the
1:09:39
audience. I see both sides. I've read
1:09:41
the Israel stuff and the Palestine stuff.
1:09:43
They're both right. So guess
1:09:45
what? That's right. So at the
1:09:47
end of the day, what want me to do?
1:09:49
for Timmy's career? Is that an approach you could
1:09:51
take? What's right for me? What's the easiest lunch?
1:09:53
What's the easiest afternoon for me? What,
1:09:55
you know, that path of resistance. That's
1:09:59
the move for me, always, all
1:10:01
the time, you know? Right. So, you
1:10:03
know? Absolutely. Absolutely. What
1:10:06
Putin did, was it right? No, but
1:10:08
do I like the idea of the
1:10:10
oligarch, the furs, the boats, the kind
1:10:12
of lifestyle? Yes, the kind
1:10:14
of tracks. Yacht. Yes, that to me
1:10:16
is always spoken to me. Somebody said
1:10:18
to me once, you're spiritually Russian. So
1:10:20
I think I have that in me,
1:10:22
so I just can't ignore it. So
1:10:25
how would you rank your dictators? Sounds
1:10:28
like you're a Putin guy or you? Putin
1:10:30
has a lot of class. Whether you like
1:10:32
him or not, he has a lot of class.
1:10:34
And number one, people do fall out of
1:10:36
windows in London. It does happen, actually. It's
1:10:39
not always, you know what I mean? It's
1:10:41
like sometimes somebody does take his spell. It's
1:10:44
not always him. Um, I like
1:10:46
him. I, I like, uh, Kim,
1:10:48
I think it's Jongoon in North
1:10:50
Korea. Yes. I like him. He
1:10:52
has style as well. Don't forget
1:10:55
Zelensky. He
1:11:00
just extended military
1:11:02
rule. He
1:11:05
just extended martial law. There's no
1:11:07
election. By the way, I like
1:11:10
sacks on this. And I think
1:11:12
when they told Putin that a
1:11:14
comedian was now the president of
1:11:16
the Ukraine, Putin probably said,
1:11:18
listen, are they serious? Are
1:11:20
they even trying anymore? Because
1:11:22
is the CIA even trying
1:11:24
anymore? Are you serious? Wait,
1:11:27
the guy who played the
1:11:29
president in a TV show is
1:11:31
now the actual president? Yes.
1:11:34
And Putin's getting this information sitting there
1:11:36
in his palace. Like, I Yes.
1:11:39
So, I mean, listen, all war is tragedy.
1:11:41
It's all terrible and bad. But,
1:11:43
you know, we also... I think David's done
1:11:45
a phenomenal job, by the way, of looking
1:11:47
at how you get to certain places. Hmm.
1:11:50
Absolutely. Yeah. Yeah. And then I
1:11:52
think the, you a lot of private
1:11:54
shows. Yeah. You do a lot of
1:11:56
private shows, Tim. The private shows with
1:11:58
the dictators, the despots, the
1:12:00
monarchies, they pay what? Three to
1:12:02
one, four to one? They want to
1:12:04
laugh these people. They want to
1:12:06
laugh. Uh, you know, I mean, it's,
1:12:08
Duterte likes to laugh. So, you
1:12:11
know, these people want to laugh
1:12:13
and I'm not here. MBS wants
1:12:15
to laugh. I'm not here to
1:12:17
pass judgment on the audience. I'm
1:12:19
here to bring, well,
1:12:21
it's actually funny. I did like one private gig.
1:12:23
I don't get booked on a lot of private
1:12:25
gigs, but I got one big Bitcoin guy in
1:12:27
Romania had me go to his birthday party. And
1:12:29
it was just this older oligarch type guy. And
1:12:31
they all spoke Romanian. It was very hard. And
1:12:33
they paid me $100 ,000 to do 20 minutes
1:12:35
and they didn't really understand anything. And
1:12:37
then one guy just stood up and I
1:12:39
guess he recognized me. He started yelling, Joe
1:12:41
Rogan, Joe Rogan. And then sat down. So
1:12:44
I am open to, I'm open to
1:12:46
performing for anyone, really true. Anyone.
1:12:48
Idi, I mean, Iran, you could just
1:12:50
Kim Jong -un, just send a ticket. Hey,
1:12:53
hey, is the money green? Is the
1:12:55
money green over there? The money's not clean, but.
1:12:57
Is Iran that danger? I mean, all I
1:12:59
hear now every day is Iran's coming to kill
1:13:01
everyone. Is that true? I don't know. I'm
1:13:03
okay. Are they invading? Is Iran
1:13:05
landing an aspen? Building nukes, maybe want to
1:13:07
wipe out one or two countries. A little
1:13:09
genocide. Wish fulfillment.
1:13:12
How far are they along on those
1:13:14
nerds? We don't know that. 80 % them.
1:13:16
You think 80 %? They're perpetually
1:13:18
at 80%. We just keep knocking out the
1:13:20
last one as I can approach the... I
1:13:22
just don't think we need to put it
1:13:24
on the ground there. I don't think we
1:13:26
need to do this again. The two of
1:13:28
you are the living embodiment of ADHD. Yes.
1:13:31
Well, speaking of ADHD, do we want
1:13:33
to go ADHD or science? Tim, J.
1:13:35
Cal falls for every pro -war narrative
1:13:37
there is. Oh, absolutely. He's like,
1:13:39
I'm against war, but then he falls for
1:13:41
every single narrative they've had. Absolutely. Absolutely.
1:13:43
And you did a great job. You guys
1:13:45
have done ending the war on day
1:13:47
one of your administration. Congratulations. At
1:13:49
least he's trying. Wake me up actually
1:13:51
accomplish something. actually defend the administration?
1:13:53
We've actually ended it spiritually. We've
1:13:55
ended it spiritually. We have. We no
1:13:58
longer believe in it. It's
1:14:00
actually happening in the physical world, but
1:14:02
actually spiritually the war is over. Yes.
1:14:04
So you're manifesting the end of the
1:14:06
war. Well, it's over for me. The Ukraine
1:14:08
war is fully over for me. God.
1:14:11
So Lyski refuses to make a deal. You saw
1:14:13
what happened at the White House. I mean, if only
1:14:15
we had a dealmaker to help with this. Jason,
1:14:17
you know how you would know this for sure? Because
1:14:19
my intuition tells me that what
1:14:22
Tim just said is totally right is...
1:14:24
number of Ukraine flags that were
1:14:26
taken off of profile photos. Absolutely. I
1:14:28
don't want the pronouns. No, even
1:14:30
though it's a joke, I am being
1:14:32
very dead serious. The idea of
1:14:35
it has ended. It is now just
1:14:37
about a border negotiation. It
1:14:39
is no longer a
1:14:41
totemic struggle for freedom
1:14:43
or whatever it was
1:14:45
being sold to us
1:14:47
as. Totally agree. Takeout
1:14:50
still believes that. You can
1:14:52
speak for yourself. I
1:14:55
believe the free countries, just to be
1:14:57
clear, I believe the free countries should
1:14:59
stop the non -free countries from invading them.
1:15:01
That's it. It's a pretty simple philosophy.
1:15:03
Freberg, well, what's science? Tim, at the end of
1:15:05
the show, we like to do a little
1:15:08
corner. What are some of those vice documentaries about
1:15:10
the Ukraine being the most corrupt country in
1:15:12
Europe and like a white supremacist country and all
1:15:14
these things? What happened to all those vice
1:15:16
documentaries about that? They seem
1:15:18
to disappear very quickly.
1:15:20
when Ukraine became a
1:15:22
bastion of freedom and
1:15:24
love and opportunity and
1:15:26
equality. Now you're speaking Saxon's language.
1:15:28
Well, look at that smile on face.
1:15:30
Well, Nick, just put this on the screen. I mean,
1:15:33
this just happened yesterday. Oh, God.
1:15:35
But now we've started the Ukraine. Ukraine's
1:15:37
problem the sense martial law till August. That
1:15:39
seems extreme. Yeah,
1:15:42
no big deal. They cancel elections. They cancel
1:15:44
freedom of the press. They cancel freedom of
1:15:46
religion. So Linsky's political opponents,
1:15:48
their assets have been seized. They've been imprisoned.
1:15:50
No big deal. It's still democracy. His
1:15:53
favorite dictator is Putin as
1:15:55
well. Hey, Dave Freiburg. Tell the
1:15:57
first leader after 9 -11 to
1:15:59
call the United States in
1:16:01
express sympathy. I believe it was
1:16:03
Vladimir Putin. And how many
1:16:05
times has Vladimir Putin threatened American
1:16:07
interests over the last 20
1:16:10
odd years? Like, has Vladimir Putin,
1:16:12
has Russia been an existential
1:16:14
threat to America? Have they
1:16:16
disrupted huge amounts of our
1:16:18
trade? Have they It
1:16:21
seems to be very hard. wanted to be
1:16:23
a NATO. He wanted to be our ally. We
1:16:25
were buffed him. But you know what the
1:16:27
best quality of Putin is? We're not funding him.
1:16:30
He's not asking for American money. The rest of these
1:16:32
dictators, we keep funding. He's not asking for a
1:16:34
dollar. I also like that he's well -read. But
1:16:38
he's not coming to the White House
1:16:40
begging. He's not coming to the White House
1:16:42
every three months begging for more hundreds
1:16:44
of billions. But
1:16:46
any criticism of the Ukraine war means that
1:16:49
you love Putin and want to live
1:16:51
in Russia and think Russia is great. It's
1:16:53
a very weird, mannequin sense of good
1:16:55
and evil that was instituted by George W.
1:16:57
Bush right after 9 -11 when he said,
1:16:59
you're with us or against us. And
1:17:01
with us means we're going to democratize the
1:17:04
Middle East, which I fell for because
1:17:06
I was 17 and uncooking. But in hindsight,
1:17:08
it didn't work tremendously well. And
1:17:10
I just, it's always very skeptical. I'm
1:17:12
very skeptical of these narratives where they say,
1:17:14
so if you find any fault at
1:17:16
all in what you're doing, in what we're
1:17:18
doing, you're giving, you're aiding and abetting
1:17:20
a dictator. It makes no sense to me.
1:17:22
Speaking of the 90s in cocaine, Freedberg,
1:17:24
what's in corners? You'll notice he's moving on,
1:17:26
Tim. He does not respond to that. Freedberg
1:17:29
is really upset the last couple of
1:17:31
weeks that he got preempted. I'm trying to
1:17:33
do right by Freedberg and the Freedberg
1:17:35
stands. who are just absolutely mental now that
1:17:38
we haven't talked about his incredible victory
1:17:40
on Jeopardy. And we haven't gotten to Science
1:17:42
Corner in a couple of weeks. Congrats. Tim, if
1:17:44
you were ever, what game show do you want
1:17:46
to be on, Tim? None of them. None
1:17:48
of them. None. All the money on Celebrity Jeopardy.
1:17:50
would you want to host, Tim? No game shows. You
1:17:53
wouldn't host a game show. You must have been offered. No,
1:17:55
never. I don't think I'm
1:17:57
what they want for the game show. a
1:17:59
money printing machine. You could get in a
1:18:01
game show, Family Feud or something. No, but
1:18:03
I do. It all goes to
1:18:05
charity. Was it Freeberg? Was it hard?
1:18:09
Yeah, well, I shot the quarterfinal and semifinal
1:18:11
in the same afternoon. So I didn't
1:18:13
have any, know, you go away for lunch
1:18:15
and you come back for the semifinals. And
1:18:18
I did not know how to use
1:18:20
that buzzer. And everyone else, I think,
1:18:22
had practiced or figured that stuff out.
1:18:25
So it was pretty difficult. And then
1:18:27
my brain was just blank on some
1:18:29
of these moments. You're just up there.
1:18:31
There's this intensity. You're in this game show. And
1:18:34
it's like, I know the answer. Why is it not
1:18:36
coming out of my mouth? Or why did I say that
1:18:38
thing that I know is wrong that just came out
1:18:40
of my mouth? It's a little bit kind of scary. Let's
1:18:43
show the clip here, and then we'll go
1:18:45
on to Science Corner. Watch this clip. Watch
1:18:47
this. Final Jeopardy. I'm in the last place.
1:18:49
So I was behind the entire game. I
1:18:51
was basically in last place the whole game.
1:18:53
Playing catch up. I could not buzz in
1:18:55
in time. Yeah. It all comes down to
1:18:57
this. Final Jeopardy in a very close game.
1:18:59
So exciting. This is the category. Here's
1:19:02
the clue, players. Mon Freedberg called
1:19:04
the premier movie industry event for
1:19:06
the Balkans. This festival began
1:19:08
30 years ago while the city was
1:19:10
under siege. We'll begin on the end
1:19:12
with Dave Freedberg who had $8 ,700. And
1:19:15
it looks like he changed his answer at
1:19:17
the last minute. What happened here? He wrote
1:19:19
down something and crossed it out and wrote
1:19:21
Sarajevo Film Festival. We can read Sarajevo, and
1:19:23
that's the important part, right? We're going to
1:19:25
give you credit. You wagered
1:19:27
$8 ,697, and now you have
1:19:29
$17 ,397. You're ahead of Mina
1:19:32
Kimes at the moment with
1:19:34
$17 ,000. What did she put
1:19:36
down? I did my math wrong.
1:19:38
Oh, She wrote down can, and
1:19:41
she wagered. What? A
1:19:43
thousand that drops her down to
1:19:45
16 ,000 So it comes down
1:19:47
to shongan who had 22 ,000. Did
1:19:50
he know one either way avo
1:19:52
film festival? He said Bosnia right
1:19:54
country wrong city. What did you
1:19:56
wager? 12 ,001 9 ,999 and from
1:19:58
he could just stay free
1:20:00
bird come What did he do? Can
1:20:03
I ask a question and this
1:20:05
is a very this is a
1:20:07
serious question and it is not
1:20:09
disrespectful Why do they
1:20:11
call this celebrity Jeopardy? You're correct. I
1:20:14
did not identify one
1:20:17
of those people with a
1:20:19
gun to my head. I
1:20:22
don't know. There were 27. I didn't
1:20:24
know any of them. I felt in place.
1:20:27
I mean, I think the guy
1:20:29
in the middle with James
1:20:31
Gunn's brother, who was in, he
1:20:33
played like the 17th guy
1:20:35
in Guardians of the Galaxy. What
1:20:37
is happening? I mean
1:20:39
if you're going to Marvel universes
1:20:41
characters speaking roles pull him up
1:20:43
for a second. He has non -speaking
1:20:45
role in a Marvel movie. There's
1:20:47
1400 Marvel movies and this guy
1:20:49
hasn't spoken to one. Come on
1:20:51
stop. Him. That's
1:20:54
Marvel... Who was the other
1:20:56
lady? I think
1:20:58
she's... Who's that? I
1:21:00
mean... She's on ESPN.
1:21:02
A researcher on ESPN. And
1:21:04
she does fencing, right?
1:21:07
She's the fencing person from
1:21:09
ESPN. Oh, I think
1:21:11
she covers football at ESPN. Football
1:21:13
or football? Was
1:21:15
this actually celebrity Jeopardy or
1:21:18
is this just like Jeopardy?
1:21:20
Just call it Jeopardy. Just
1:21:22
call it Jeopardy. Easy Jeopardy.
1:21:24
Just call it Jeopardy. Just
1:21:26
call it hey, we're doing
1:21:28
this thing now. They should
1:21:30
do a comedian. Okay,
1:21:33
the finals are next Wednesday at 9
1:21:35
p .m. Have you actually done the episode?
1:21:37
When is the final episode? How
1:21:40
do we make money at this? How do we front and run this? Oh,
1:21:42
he's done it already. So you know the winner. Why don't
1:21:44
we do a poly market for this? And we could
1:21:46
all cash in and get off this show. We
1:21:49
could all just cash in. Somebody
1:21:53
to shoot this dog. There is a
1:21:55
dollar number, J .K .L. Are
1:21:58
people watching this? 10 times
1:22:00
30 million, 10 times 40 million.
1:22:03
35%. Who's the first? Actually,
1:22:06
Tim's asking, do
1:22:08
the ratings go up or down for celebrity
1:22:10
jeopardy? Down. Certainly
1:22:12
down. They used to be good. So
1:22:14
I think regular, well, they do it at
1:22:16
9 PM on Wednesday nights. Okay. So
1:22:18
it's not even during. Upside
1:22:20
for celebrity to go on this. If a celebrity goes on
1:22:22
this and they're known for being smart, if George Clooney
1:22:24
goes on, right? Exactly. I realize this when I got there.
1:22:26
I'm like, wait a second. There's no upside in me.
1:22:29
doing this, I'm going to look like an idiot and I
1:22:31
answered all these stupid questions wrong and I look like
1:22:33
a moron. I'm like, why did I do that? No,
1:22:35
it's a stupid show
1:22:38
that should go away. No,
1:22:43
I mean, it's like this idea that
1:22:45
like all these people that nobody knows
1:22:47
the hell they are, it just, you
1:22:49
know, the people at home are going,
1:22:51
who the hell? What the fuck is
1:22:53
this? The lady from
1:22:55
ESPN says, caught like she thinks
1:22:58
it's in France. This
1:23:00
is just making people mad that go, hey
1:23:02
man, I got nothing going on, and these
1:23:04
people are celebrities or idiots. I
1:23:06
mean, same continent? She hit the same
1:23:08
continent, right? It's just filling people with rage,
1:23:11
looking at these people that aren't even
1:23:13
celebrities, and on top of that are morons.
1:23:15
I mean, you have an obligation to either
1:23:18
be a celebrity or be a nerd.
1:23:20
It did say the Balkans. the
1:23:22
Balkans. It did say the Balkans. This is a
1:23:24
little rough, I mean. A
1:23:26
little brutal. Hey, save the show,
1:23:28
Dave. Please, give us science corner. I'll
1:23:30
do a quick science corner. And
1:23:33
the name of the game here, Tylan, just since your
1:23:35
first time on the show, is somehow,
1:23:37
if you can get around the horn and
1:23:39
put in a Uranus joke, you'll just
1:23:41
kill with the audience. I'm going to try to
1:23:44
do that. My producer right now, we're setting up a
1:23:46
company in Bhutan. That's my whole
1:23:48
thing now. Oh, you're going to be flipping
1:23:50
H -100s. But I just learned so much on
1:23:52
the front half of the show. It's
1:23:54
a company in Bhutan. Give us
1:23:56
the chips. Wink, wink. They're
1:23:58
not going to Beijing at all. Wink. My godsons,
1:24:00
Chinese. They go in the back, they go through
1:24:02
the front, maybe the side door. My godsons, truly,
1:24:05
I swear to God, they brought him to my
1:24:07
home when he was four months old, because they
1:24:09
know I'm single and I have a little bit
1:24:11
of money, not compared to you, but compared to
1:24:13
these people. And they said, would you be his
1:24:15
godfather? He's Chinese. Absolutely, I
1:24:17
said, high end, let's go. Four years later,
1:24:19
they tell me, they go, he's actually
1:24:21
Filipino. I'm not even kidding. So
1:24:23
this is why you can't
1:24:26
trust anyone in this country
1:24:28
about anything. Even your adoption,
1:24:31
your... Wow. A
1:24:33
corrupt adoption. Okay, let's
1:24:36
do science corner. Science corner.
1:24:38
Mitochondria or... Today is Mitochondria
1:24:40
Therapy Day. So every
1:24:42
cell in our body has mitochondria.
1:24:45
Tim, you know that, right? Yeah, it's
1:24:47
the powerhouse of the cell. Powerhouse in
1:24:49
a cell exactly and it's a little
1:24:51
organelle segment. Yeah, you can drop
1:24:54
off sex. Okay. See you later Okay,
1:24:58
yeah. Excellent. I'll
1:25:00
see you at the Food Film Festival. You
1:25:05
forgot to say what is. I'll
1:25:08
see you at the Moscow Film I mean,
1:25:10
yeah, I need to run to Sean Hannity's show,
1:25:12
unfortunately. Sorry, no,
1:25:14
unfortunately. Don't say unfortunately. You
1:25:16
can leave that in. I like him. Absolutely.
1:25:18
He's amazing, yes. I really enjoy you guys.
1:25:20
Thank you for having me on. I really
1:25:23
learned this was amazing. And
1:25:25
I'd love to do it again. I
1:25:27
appreciate all of you. I
1:25:29
think you're all great. And
1:25:32
whatever you're doing on the side,
1:25:34
whatever you people eventually get arrested for,
1:25:36
I support you. Just know that.
1:25:38
I'm a supporter of whatever happens at
1:25:40
the oil and podcast. Whenever
1:25:43
it comes out that there's a reason
1:25:45
why you knew so much about the
1:25:47
Bhutan company, it doesn't matter to me.
1:25:49
I'm a fan. Thank
1:25:52
you everybody watched
1:25:54
him Dylan special
1:25:56
on the Netflix.
1:25:58
Hopefully he can
1:26:00
he was great
1:26:03
finally Eclipse love
1:26:05
on the spectrum
1:26:07
love on the
1:26:09
spectrum Okay And
1:26:12
then there were three, you know what? As
1:26:15
a standalone show and we're gonna
1:26:17
side with you you do tabs
1:26:20
corner with me. I'm going to
1:26:22
eat lunch. I love you guys
1:26:24
I got it. I got your
1:26:26
size corner. I'm with you to
1:26:28
the end brother free burdens me
1:26:30
and you buddy Tell me about
1:26:32
science quarter. I'm interested. You're interested.
1:26:34
We've got no listeners. We've got
1:26:36
no audience at this point I'm
1:26:38
here for your segment. Go ahead
1:26:41
tape Oh, for the four of
1:26:43
you and Chamath. Okay. So mitochondria
1:26:45
are the powerhouse of the cell,
1:26:47
as Tim just told us, educated
1:26:49
us, right? So every cell has
1:26:51
hundreds of mitochondria. Mitochondria
1:26:53
are what are called organelles. They
1:26:55
have their own DNA. In
1:26:57
fact, evolutionarily, mitochondria were
1:26:59
bacteria that basically ended up
1:27:01
in the symbiotic relationship
1:27:03
with what became our cells.
1:27:06
So we each have mitochondria,
1:27:08
hundreds of them in each one of our cells.
1:27:10
Each mitochondria has its own nucleus and has its
1:27:12
own DNA. And the mitochondria
1:27:14
make the energy that the rest of the
1:27:16
cell uses. That energy is called ATP, and
1:27:19
it eats up glucose or it
1:27:21
eats up ketones if you're in ketosis,
1:27:23
and it uses that to make
1:27:25
the ATP. So every cell in our
1:27:27
body gets its energy, which is
1:27:29
what it uses to function from the
1:27:31
mitochondria. And so there's been a
1:27:33
lot of research into the relationship between
1:27:36
mitochondria and aging and that dysfunctional
1:27:38
mitochondria, as they start to break down
1:27:40
and stop working and have damage,
1:27:42
may actually be a key driver for
1:27:44
many diseases that we experience as
1:27:46
humans, including many cancers, Alzheimer's,
1:27:48
Parkinson's, ALS, features of autism, muscle
1:27:50
tissues being weak, et cetera.
1:27:52
So as the cells get older
1:27:55
and the mitochondria stopped working,
1:27:57
we make new mitochondria. But over
1:27:59
time, the DNA degrades and
1:28:01
the mitochondria had become less effective.
1:28:03
And there are fewer functional
1:28:05
mitochondria per cell. The cell
1:28:07
stops working right. Can I ask you
1:28:10
question? eventually the organism stops working right.
1:28:12
Have you learned anything about the connection
1:28:14
of creatine to mitochondrial health? It's
1:28:16
part of some of the processes,
1:28:18
but there's some separate research on this,
1:28:20
but it's definitely worth spending time
1:28:22
on. We can see about
1:28:24
you taking five grams or ten grams five
1:28:26
million like a trend. Yeah, I think I know
1:28:28
five grams. Yeah, something like that. It's trending
1:28:30
on Twitter I think it's kind of like a
1:28:33
meme or a joke in addition to but
1:28:35
I don't think it's a joke is it is
1:28:37
it but it does it Is there any
1:28:39
science that backs that up or not really for
1:28:41
mitochondria? There are questions on this like do
1:28:43
you want to focus on things that are? Increasing
1:28:46
biogenesis, which is creation of new
1:28:48
mitochondria. Does that create a better benefit?
1:28:50
on the creatine work. I've read
1:28:52
some of these papers. I actually tried
1:28:54
it for a while. I
1:28:56
personally had an allergy to
1:28:59
it, which is kind of rare,
1:29:01
but happens. But
1:29:03
anyway, we can talk about it further. So
1:29:05
one of the key things was there are
1:29:07
three papers that I wanted to just highlight that
1:29:09
kind of follow an interesting theme. The
1:29:11
first one was from 2023 from Wash
1:29:13
U in St. Louis. And
1:29:16
this paper, Nick, if you could just pull
1:29:18
up that image of mitochondria
1:29:21
being transferred, these
1:29:23
folks identified and demonstrated that
1:29:25
mitochondria can actually transfer from one
1:29:27
cell to another. So
1:29:29
if you've got a cell that's
1:29:31
got damaged or dysfunctional mitochondria, they've identified
1:29:33
three mechanisms by which mitochondria can
1:29:36
move into a cell that needs
1:29:38
more mitochondria that are working and are
1:29:40
more functional. That's something that's been
1:29:42
theorized for a long time. People have
1:29:44
said, oh, well, we think mitochondria
1:29:46
transfer, but there wasn't really evidence of
1:29:48
this. So as of two years
1:29:50
ago, these guys provided very good
1:29:53
evidence of mitochondria that we can now
1:29:55
put into cells. If it's floating
1:29:57
around, it can make its way into
1:29:59
another cell. And as a result,
1:30:01
it can rejuvenate or provide energy
1:30:03
to a dysfunctional cell, which might improve
1:30:05
dysfunctional tissue or improve disease. The
1:30:08
second paper. was done last
1:30:10
month out of Columbia University. And this
1:30:12
was the first mapping of the mitochondria
1:30:14
in the human brain. And so these
1:30:16
folks created 703 tiny cubes of brain
1:30:18
from a person that passed away, a
1:30:20
54 year old donor. And then they
1:30:22
analyzed the mitochondria in each of those
1:30:24
cubes and they use that to make
1:30:26
a map of mitochondria in the brain.
1:30:28
And what it showed was that different
1:30:31
parts of the brain, different
1:30:33
cells had different amounts of mitochondria
1:30:35
and different mitochondrial function. which actually starts
1:30:37
to highlight how that difference in
1:30:39
energy production and different cells in different
1:30:41
parts of the brain may actually
1:30:43
cause some of the things like memory
1:30:45
loss or speech impairment. Or
1:30:47
as we age, the fact that
1:30:49
we end up being kind of
1:30:51
forgetful or start to lose some
1:30:54
of our capacity, that the mitochondrial
1:30:56
dysfunction in the brain might actually
1:30:58
be the key driver of that
1:31:00
aging symptomology. The third
1:31:02
paper, which just came out, came
1:31:04
out of a team at Shé
1:31:06
Xiang University in China. So
1:31:08
what these guys did, which was really incredible, is
1:31:11
they took stem cells, so stem cells that
1:31:13
they got out of human blood, and they
1:31:15
took those stem cells and they figured out
1:31:17
a way to treat the stem cells that
1:31:19
those stem cells would start to make an
1:31:21
excess amount of mitochondria than they normally would
1:31:23
make. In fact, they
1:31:25
were able to get those
1:31:28
stem cells to make 854
1:31:30
times the number of mitochondria
1:31:32
that those cells would normally
1:31:34
make. And those mitochondria were
1:31:36
on average 5 .7 times more
1:31:38
efficient at making energy ATP.
1:31:40
So they created highly energetic mitochondria and
1:31:42
they made a lot of them. And
1:31:45
the idea that we can put mitochondria
1:31:47
into our body or into tissue in our
1:31:49
body to heal it or repair it
1:31:51
has been something that folks have been trying
1:31:54
to do research around for a long
1:31:56
time. But the limiting factor is access to
1:31:58
enough mitochondria. So this mechanism that they
1:32:00
developed where they could take stem cells make
1:32:02
copies of the stem cells, make lots
1:32:04
of mitochondria, and then they isolate that mitochondria
1:32:06
and use it as a therapeutic tool.
1:32:08
And they did it in cartilage that was
1:32:10
damaged and they were able to heal
1:32:12
that cartilage. So this is a
1:32:15
group that does bone and tissue
1:32:17
repair studies, but they applied the mitochondria
1:32:19
directly into the area where there
1:32:21
was damage to the bone and the
1:32:23
bone grew back and it actually
1:32:25
improved the healing in an incredible way.
1:32:27
So this opens up the door
1:32:29
to this whole new therapeutic modality, a
1:32:32
new type of therapy called mitotherapy
1:32:34
or mitochondrial therapy, that based on the
1:32:36
series of papers that we're seeing
1:32:38
coming out recently, I believe could end
1:32:40
up becoming a really incredible new
1:32:42
therapy that may ultimately lead to the
1:32:44
treatment for many diseases that we're
1:32:46
kind of dealing with right now. So
1:32:49
I just wanted to kind of
1:32:51
link those out. this be immediately applicable
1:32:53
to say people with sports injuries,
1:32:55
you know, meniscus, knees, ankles? You start
1:32:57
to think about those bone spurs,
1:32:59
chips. that basketball players, football players go
1:33:01
through, would this be like the
1:33:04
low -hanging fruit for this technology? Yeah,
1:33:06
I mean, what they did this in, and
1:33:08
I think this was published in a research
1:33:10
magazine called Bone or something, Bone and Tissue
1:33:12
or something. Yeah. But they did it
1:33:14
an I let my subscription lapse, I got a reminder. They
1:33:17
did it in a in a model,
1:33:19
a mouse model of osteoarthritis, and it
1:33:21
repaired this osteoarthritis, but that's exactly right.
1:33:23
And so that's tissue where you can,
1:33:25
using a microscope, you can actually see
1:33:27
the healing happening. You could see this
1:33:29
being applied for example to cerebrospinal fluid
1:33:31
where you could basically increase the mitochondrial
1:33:33
the energetic mitochondrial production That finds its
1:33:35
way into maybe neuronal cells into neurons
1:33:38
in your brain and improve your brain
1:33:40
function Or you could put it into
1:33:42
damaged hearts after heart attacks and improve
1:33:44
heart function So there's all these theories
1:33:46
about how you could use mitotherapy as
1:33:48
this becomes possible to now produce lots
1:33:50
of mitochondria and use it as a
1:33:52
therapy that can then be applied to
1:33:54
lots of disease. I think there's to
1:33:56
be a bit of a blossoming of
1:33:59
research in this area. They could take
1:34:01
this if they can get this going
1:34:03
in the next two years or so.
1:34:05
They could get this and Biden could
1:34:07
actually compete with Trump for his third
1:34:09
term if they could get this to
1:34:11
Biden in time. I
1:34:13
mean, that's microphone on. That's
1:34:15
exceptionally low. And I think that that's just
1:34:18
charm. Oh, now all of a sudden you're defending.
1:34:20
By the way, did you guys see did
1:34:22
you guys see George Clooney? What
1:34:24
do you guys think of his new haircut,
1:34:26
his hair color? I noticed he
1:34:28
was, he's dying his hair. He was gray
1:34:30
and now he looks - It must be a,
1:34:32
for an acting job because his hair -
1:34:35
I hadn't seen this, this is crazy. He
1:34:37
looks - It looks like his face is melting.
1:34:39
Oh my God, he looks looks like he
1:34:41
did a, I don't know, like
1:34:43
what do they call that hair coloring for men?
1:34:45
Like you put it in the shower, it looks
1:34:47
very weird. Well, he just did an interview explaining
1:34:49
his whole op -ed on Biden, but it's in that
1:34:51
clip where he looks very different. What did he
1:34:53
say on Biden? I thought he looked really, he
1:34:55
said he felt compelled to act and that it
1:34:57
was a civic duty, although the dates don't match
1:34:59
up, but nobody ever questioned him about that. But
1:35:02
he, he looks really good. He did not get
1:35:04
a call from Obama. and pepper here. Salt
1:35:06
and pepper works a hundred percent. What does he do
1:35:08
here? Clooney's a very handsome guy, but in that, in
1:35:10
that interview, he did, I don't think he looked perfect.
1:35:13
You guys watched the white lotus, by the way. Did
1:35:15
you guys watch the white lotus? What did we think?
1:35:17
Okay. So I don't know what it was, but I
1:35:19
had heard from a bunch of you guys in the
1:35:21
group chat that the show was not good. So Nat
1:35:23
and I ignored it. Then we started it. We watched
1:35:25
one episode. Phenomenal. Oh,
1:35:27
you loved it. Well, we're one
1:35:29
episode in, but it was great.
1:35:31
And we were like, this is
1:35:33
really good. And then, you know,
1:35:35
I don't think it's terrible. And
1:35:37
the kid Schwarzenegger, Patrick Schwarzenegger is
1:35:39
a fan of all in, apparently.
1:35:41
Patrick Schwarzenegger. I can
1:35:44
tell that that guy has
1:35:46
one of the most
1:35:48
interesting roles. in that series,
1:35:50
I'm really looking forward to him. Who
1:35:53
else was really cool? DM the other
1:35:55
day, we were following each other. I saw
1:35:57
and he said, great pod. He DMed
1:35:59
me and said, great pod. And I said,
1:36:01
great job. And then I mentioned, you
1:36:04
know. Patrick Schwarzenegger is your friend? Well,
1:36:06
I guess it's like, what does it
1:36:08
mean? Like micro celebrity DM friends? I
1:36:11
don't know. You could be on Celebrity
1:36:13
Jeopardy. I could literally be on Celebrity
1:36:15
Jeopardy. I think. I think I
1:36:17
would prefer to do Hollywood Squares. I feel like
1:36:19
Hollywood Squares, I could shine because you get a
1:36:21
little one -liners in, like the jokes are kind
1:36:23
of built into it. A lot more fun. But
1:36:25
I think we should do Family Feud versus another
1:36:27
podcast squad. So like us versus -
1:36:29
Why do you aim so high always? Well,
1:36:31
I think Family Feud's funny. I think it's funny. All
1:36:34
right, everybody, this has been another - That would be
1:36:36
a lot of fun. That's a good idea. In fact,
1:36:38
we should do it with Schultz and his crew. The
1:36:40
four of them and the four of us. Yes, Paulin
1:36:42
Vols is Schultz -y in his crew. That'd be hilarious. Eight
1:36:44
people would watch. No,
1:36:46
you're incorrect. No, people
1:36:48
would love it. Yeah. Yeah. This
1:36:50
is definitely something for John to get on. If
1:36:52
we're done sniffing our own butts, let's go. We
1:36:55
gotta go. Okay. Love you guys. you.
1:36:57
For the number one podcast in the
1:36:59
world, Shamath Pahlihapatiya, your chairman, Dick Payton,
1:37:01
David Freberg, yourself in the science, Tim
1:37:03
Dillon. Great job today,
1:37:05
and we will see all. And David
1:37:07
Sacks. Don't forget David Sacks. I'm sorry.
1:37:09
The czar. The czar.
1:37:11
Huzzah to the czar, who
1:37:14
apparently is back. I was
1:37:16
back. Love you boys. All
1:37:18
in Summit, September 7 to 9.
1:37:20
Bye -bye. All in fan meetups are
1:37:22
happening. Episode 225, Saturday, April 26. Go
1:37:24
to allin.com slash meetups to join
1:37:26
and meet and host a meetup with
1:37:29
other All in fans in your
1:37:31
town. We'll see you all next time.
1:37:33
Bye -bye. We
1:37:44
open source it to the fans, and
1:37:46
they've just gone crazy with it. Love you,
1:37:48
Wes. I'm Queen of Kinoa. I'm going
1:37:50
all in. Besties
1:37:56
are gone. This is
1:37:58
my dog taking a notice in
1:38:00
your driveway. set up. Oh, man.
1:38:03
Oh, man. He We
1:38:05
should all just get room and just have
1:38:08
one big huge orgy, because they're all just
1:38:10
useless. It's this like, sexual tension, that we
1:38:12
just need to release somehow. What?
1:38:14
You're a bee. What?
1:38:16
You're a bee. What?
1:38:18
You're a bee. We need to get merch. I'm
1:38:21
going all in. What?
1:38:29
What? going all in.
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