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try at mintmobile.com, Invidia,

12:07

Meta, Amazon, Microsoft, and Alphabet

12:09

all saw big gains as

12:11

well. But at the time

12:13

of this recording, markets have

12:15

gone south once again with

12:17

NASDAQ dropping 5.9% all of

12:19

this just punctuationability of big

12:21

tech in a, let's say,

12:23

dramatic moment of flux for

12:25

the industry. Yeah, when prepping this show,

12:27

you know, and I got this from

12:30

Tom, I'm always kind of like looking

12:32

for the consumer angle on stories like

12:34

this, because we're not really a stock

12:36

market show, you know, where, like, I'm

12:38

not invested in any stock, so it's

12:40

not my cup of tea. But I

12:42

do think it's important to note this

12:44

particular part of the story, because we've

12:46

been so used to stability. and to

12:48

by a large degree in big tech.

12:50

And right now, things are swinging from

12:52

best day to worst day back to

12:54

best day in a matter of like

12:56

three days. It's really remarkable what's

12:58

going on right now. Yeah, and you can't

13:00

help that won't impact their strategies and

13:03

thus at the very tail end, us

13:05

as consumers. So. 100% and this

13:07

ties right into what you

13:09

just said. If you feel

13:12

like you are suffering from

13:14

a case of tariff whiplash,

13:16

laptop company framework knows firsthand

13:18

how you feel, they announced

13:20

10% price hikes yesterday on

13:22

all of their computers. only

13:25

to then revert to their

13:27

normal pricing one hour later

13:29

after immediately catching wind of

13:31

the 90-day pause on tariffs

13:33

in the US almost, you

13:36

know, immediately after they posted

13:38

that update. Some prices

13:40

will still reflect the

13:42

tariff increases that are

13:44

remaining in China, however. As

13:46

they say, timing is everything.

13:48

Well, Open AI is striking back

13:51

and countersuing Elon Musk, accusing him

13:53

of harassment and disruptive tactics aimed

13:55

at interfering with its transition to

13:57

a for-profit mode. That trans- is

14:00

critical to the company securing for

14:02

$40 billion in funding by your

14:04

end. And Open AI says Musk's

14:06

actions are meant to undermine the

14:08

company and gain him an advantage

14:10

for his rival AI firm, XAI.

14:12

A jury trial is set for

14:14

sometime this spring. We're basically watching

14:16

like an AI version of tennis

14:19

right now. It's like back and

14:21

forth, back and forth. Microsoft's April

14:23

2025 security updates have caused login

14:25

issues for some Windows users who

14:27

rely on the Windows Hello authentication

14:29

system. Some devices running Windows 1124H2

14:31

or Windows Server 2025 with security

14:33

features like dynamic root of trust

14:35

for measurement or system guard secure

14:37

launch enabled are the ones who

14:39

are experiencing these login issues while

14:42

attempting to perform push button reset.

14:44

or reset this PC with to

14:46

keep my files option. I know,

14:48

this is all very specific. And

14:50

as a not Microsoft person, I'm

14:52

basically reading Greek right now, but

14:54

I'm sure this speaks to someone

14:56

out there. Microsoft has provided a

14:58

temporary work around if this is

15:00

you while they work on a

15:02

permanent fix. Well, Tesla has officially

15:05

entered the Saudi Arabian market for

15:07

the first time, though the company

15:09

faces significant challenges there. infrastructure is

15:11

underdeveloped with only 101 charging stations

15:13

mostly in urban areas. Long distance

15:15

travel is hindered by the lack

15:17

of chargers on major routes like

15:19

the Riyadh Mecca Highway, which stretches

15:21

559 miles without a single charter.

15:23

The move follows improved relations between

15:25

Elon Musk and Saudi leadership after

15:28

a 2018 feud over a failed

15:30

privatization deal. Yeah, Tesla really wants

15:32

to be there. It's been a

15:34

it's been a challenge to say

15:36

the least so far. It sounds

15:38

like some of the moves that

15:40

are happening between the US and

15:42

Saudi Arabia right now has Musk,

15:44

you know, really hitting hard on

15:46

striking these deals in there. so

15:48

that Tesla is in place when

15:51

some of these upcoming changes possibly

15:53

go into place so that he

15:55

can stand a benefit because there's

15:57

a lot of external competition there

15:59

as well. So important market I

16:01

think for Musk right now. Google

16:03

announced plans to integrate Anthropics model

16:05

context protocol, also known as MCP,

16:07

into its Gemini AI models and

16:09

SDK. Open AI recently adopted the

16:11

open source standard as well. You

16:14

may remember. The move aligns Google

16:16

with other companies supporting the protocol

16:18

like Block and Replit. Replit? Replit?

16:20

Replit? I'm not really quite sure

16:22

how to say that actually. Now

16:24

that I say that out loud.

16:26

Signaling its growing importance in supporting

16:28

interoperability and scalable AI-powered application. Well,

16:30

I'm down with MCP. You know

16:32

me, but I know you You've

16:34

got you've got a teacher that

16:37

says that right? That's how much

16:39

you're down with it. Yeah, absolutely.

16:41

Well, I mean, yeah, interchange is

16:43

always a good thing. So 100%

16:45

Well, during Google cloud next event,

16:47

the company quietly launched a Firebase

16:49

studio a cloud based platform that

16:51

brings vibe coding to life for

16:53

developers and non-developers. The platform is

16:55

browser-based and integrates generative AI into

16:57

the entire app development process from

17:00

prototyping to deployment. Gemini AI is

17:02

combined with tools like Gen Kit

17:04

and Project IDX to drive app

17:06

design through natural language, images, or

17:08

pre-built templates. Firebase Studio is in

17:10

preview now. And you're going to

17:12

do some vibe coding or what's

17:14

the deal? Okay, so I'm an

17:16

old lady programmer. So if I

17:18

never hear the phrase vibe coding

17:20

in my life again, I'll be

17:23

happier. But I like the intention

17:25

of it and actually Firebase is

17:27

a really important tool for us

17:29

and your developers and a lot

17:31

of different people. It's this really

17:33

cool, you know, a back end

17:35

of the service. You can get

17:37

all kinds of stuff that you

17:39

would need for a full like

17:41

app. like all in one place.

17:43

So this makes just a ton

17:46

of sense. Like it's not just

17:48

vibe coding where you could just

17:50

like throw a sudden together and

17:52

it kind of works and it's

17:54

cool. because you kind of got

17:56

your crazy idea. You could also

17:58

make it a really grown up

18:00

app as well if I'm understanding

18:02

and if Firebase includes a lot

18:04

of the other stuff. This is

18:06

kind of a big deal. And

18:09

I do love that that kind

18:11

of link between design and development

18:13

is always been kind of like

18:15

a hard like link for like

18:17

a lot of average people like

18:19

myself or average of myself who

18:21

have no design talents. So I

18:23

am excited and I'm gonna use

18:25

this. I would approve, I will

18:27

say thank you and... And you'll

18:29

re-gift it. Never wear it. I

18:32

wouldn't re-gift it from you, Jason,

18:34

but I would... It's okay, I

18:36

get it, I understand. The creators

18:38

of the Flipper Zero have introduced

18:40

the Busybar, a productivity tool with

18:42

a customizable LED display that can

18:44

act as a tech forward alternative

18:46

to traditional do not disturb signs.

18:48

It has preset and custom messages,

18:50

a countdown timer, features an eight-hour

18:52

battery, a scroll wheel for control,

18:55

and a large button on the

18:57

top, toggle statuses like busy or

18:59

on a call. Also integrates with

19:01

smart home devices and apps, via

19:03

Wi-Fi, via Wi-Fi, or you. SBC,

19:05

according to the site, sales of

19:07

the busybar start soon for $249.

19:09

I'm totally buying that. Well, Dig,

19:11

the social news site recently reacquired

19:13

by original founders Kevin Rose and

19:15

Alexis Elhian is offering an early

19:18

access program called Groundbreakers for a

19:20

one-time fee of $5. Dig says

19:22

the fee is meant to keep

19:24

out bots and plans to send

19:26

proceeds to a community-chosen nonprofit. Groundbreakers

19:28

will get firstives on user names,

19:30

a badge in the profile, and

19:32

access to behind-the-scenes, scenes, updates, mock-ups,

19:34

and experiments as the site rebuilds.

19:36

I mean, $5? That's nothing. For

19:38

Dig? I mean, Dig's classic. I

19:41

think I'm probably going to do

19:43

this. Me too. Well, those are

19:45

the essentials for today. Let's dive

19:47

a little deeper in the ongoing

19:49

stories and follow-up. You likely have

19:51

not been able to. the headlines

19:53

that say that dire wolves are

19:55

back. Well, are they? Tom asked

19:57

Dr. Nikki. So Tom, have you

19:59

watched Jurassic Park? I have, yes,

20:01

multiple times. What was your ethical

20:04

takeaway from that movie? Just because

20:06

we can doesn't mean we should.

20:08

Isn't that the ethical takeaway of

20:10

Jurassic? So I think you would

20:12

not have a chance of working

20:14

at colossal biot sizes because they

20:16

had a different takeaway. Friends again,

20:18

colossal biosciences. Yes, I feel like

20:20

colossal these days every time they

20:22

come out with a story, they're

20:24

waiting for me to go on

20:27

DTNS and talk about it. So

20:29

here we are. Yes, thank you

20:31

colossal for giving Dr. Nicki topics

20:33

for DTNS. I love it. And

20:35

we're going to debunk it. So

20:37

this came out on March 7th.

20:39

Colosso biases spread their, the word

20:41

of their latest PR stunt, which

20:43

came in the form of two

20:45

very cute little puppies that they

20:47

have been calling and I use

20:50

hand quotes here, dire wolves. They

20:52

named them Romulus and Remus. Of

20:54

course they did after the founders

20:56

of Rome. They also have a

20:58

younger sister named Kalesi because of

21:00

course they did. Of course. As

21:02

is usually the case with the

21:04

last few stories about colossal, these

21:06

puppies are not quite what they

21:08

claim to be. Yeah, I think

21:10

most people know dire wolves from

21:13

Game of Thrones, whether it's the

21:15

book or the TV show, but

21:17

there was a real thing that

21:19

was a dire wolf. What was

21:21

the actual dire wolf? Yeah, and

21:23

Tom you're near LA, right? Yeah.

21:25

So have you been to the

21:27

Libera Tarpits? I have multiple times.

21:29

Have you seen the giant wall

21:31

of dire wolf skulls that they

21:33

have there? Now that you mention

21:36

it, yes, yes. One of the

21:38

coolest places in the country. I

21:40

haven't been, but I can't wait

21:42

to go. So, okay, they are

21:44

in the Libera Tarpits because dire

21:46

wolves are animals from the Pleistocene,

21:48

also known as the Ice Age.

21:50

This is an epoch that ended

21:52

about 11, 11, 11, thousand years

21:54

ago. In LA, they got trapped

21:56

in tar and then the fossil.

21:59

got pulled out in the museum,

22:01

which is how you got to

22:03

see them. So what we are

22:05

calling dire wolves are large canids,

22:07

not necessarily wolves. They look very

22:09

similar to a wolf, but a

22:11

little bit bigger and stockier. And

22:13

they're in fact genetically completely distinct

22:15

from wolves. And we figured this

22:17

out in 2021 when they were

22:19

able to pull out ancient DNA

22:22

fragments from a tooth, I believe.

22:24

So canid is the family. Is

22:26

that right? Yeah, it's a larger

22:28

family, so like dogs are in

22:30

there, wolves are in there, and

22:32

I'm trying, I think foxes may

22:34

also be in there, but I

22:36

might be wrong. But, well, dog-looking

22:38

things, but not necessarily the same

22:40

genus, and we'll get to that.

22:42

The reason that dire wolves and

22:45

wolves look similar is due to

22:47

something called convergent evolution. Have you

22:49

heard of this term before? Yes,

22:51

that's when two things evolve separately,

22:53

but they're very similar for because

22:55

of the pressures of the environment.

22:57

Yeah, perfect. And it's one of

22:59

my favorite things about evolution. I

23:01

think it's really cool. But exactly.

23:03

So these animals underwent, they lived

23:05

in... with areas with similar environmental

23:08

pressures. They're both carnivores, hunting, maybe

23:10

similar prey, and it leads to

23:12

them evolving similar adaptations and appearances.

23:14

Similarly, how the Tasmanian tiger looks

23:16

really a lot like a coyote,

23:18

despite it living in Tasmania at

23:20

the time and being a marsupial.

23:22

Oh, I didn't know that. That's

23:24

cool. Yeah, even their teeth are

23:26

very closely resembling, so it's pretty

23:28

cool. In this case, gray wolves

23:31

are Canis lupus, so they're from

23:33

the Canis genus, like dogs. And

23:35

dire wolves are from a completely

23:37

different genus, anosion, if I hopefully

23:39

pronounce that right, anosion diaris. And

23:41

as our friend of the show,

23:43

Riley Black, mentioned on Blue Sky,

23:45

the last time they shared a

23:47

common ancestor was five million years

23:49

ago. So pretty far apart. A

23:51

little ways back, yeah. Before my

23:54

time. So did colossal make a

23:56

dire wolf and deextincted quote unquote?

23:58

I'm guessing the answer, but tell

24:00

me. Yeah, as you may now

24:02

have followed of our past stories,

24:04

including last month's woolly mouse, your

24:06

hunch is correct. They did not

24:08

quite deextincted as they claim. They

24:10

did a lot of work for

24:12

a giant PR stunt and we'll

24:14

get to why I think that's

24:17

weird. But as the scientists at

24:19

colossal did decipher some parts of

24:21

the dire wolf genome using these

24:23

ancient DNA samples I'm assuming from

24:25

the previous study, they inserted them

24:27

then into certain gene areas of

24:29

the gray wolf and they used

24:31

domestic dogs as surrogates to carry

24:33

gene edited pups. And they report

24:35

that these pups are white. You've

24:37

probably seen the picture at this

24:40

point. They're pretty stocky. They're stockier

24:42

than a gray wolf, like thicker

24:44

limbs and skulls, and also they

24:46

howl differently. It sounds like you

24:48

can make an argument that there

24:50

are, there is dire wolf in

24:52

these pups, but would you define

24:54

them as being a dire wolf?

24:56

A few edited genes does not

24:58

a dire wolf make, as far

25:00

as I'm concerned. A wolf has

25:03

19,000 genes. We've got about 30,000.

25:05

And colossal scientists made 20 edits

25:07

within 14 genes of the gray

25:09

wolf. So this is more like

25:11

a clone of a gray wolf

25:13

with 20 gene edits. Some of

25:15

some people have called this a

25:17

vaporware wolf to me. It's like

25:19

putting genetic makeup on a pig.

25:21

It basically disregards the reality of

25:23

what this species actually was and

25:26

how it lived and instead just

25:28

pulls out selected aesthetic traits that

25:30

are going to make for a

25:32

good new stunt. And it sticks

25:34

them in another species. So and

25:36

that's not even counting for if

25:38

you really want to get deeply

25:40

into genetics. Maybe you've heard that

25:42

environment can affect your genes like

25:44

how, you know, don't eat micro.

25:46

plastics because it can have some

25:49

detrimental effects. Yeah, go ahead. So

25:51

why do this? Like I understand

25:53

that. Hold on, hold on, I'm

25:55

building up to that. I will

25:57

continue on environmental effect just to

25:59

be clear. Like imagine if this

26:01

was a real dire wolf. Things

26:03

like variations in hormone levels, temperature,

26:05

it was cold during the ice

26:07

age, parental investment even. here they're

26:09

raised by I think hounds, dogs,

26:12

domestic dogs. These things can all

26:14

change the genetic pathways of how

26:16

the offsprings grow during, you know,

26:18

the embryonic phase and later. And

26:20

of course, none of that is

26:22

captured in this minimal gene edits,

26:24

just looking for a cool phenotype.

26:26

So to your point. Why? Yeah,

26:28

it seems like this is something

26:30

that there's some there is actual

26:32

science to it. They are actually

26:35

taking, you know, ancient DNA. They

26:37

are putting it in a living

26:39

animal and makes a viable animal.

26:41

But I'm not sure what you

26:43

get out of doing it here

26:45

other than being able to make

26:47

the headline that says dire wolf

26:49

DNA is in the pub. And

26:51

I agree with you, I have

26:53

a hard time wrapping my head

26:55

around this. It feels almost like

26:58

colossal is more of an entertainment

27:00

company almost than a science company.

27:02

However, it's a ridiculous amount of

27:04

work to do what they did.

27:06

And I want to break down

27:08

the steps to show you just

27:10

how much work this would be.

27:12

And every step is also 10

27:14

times more work than it sounds

27:16

because it's science. So first they

27:18

had to acquire ancient Darwin specimens

27:21

from a that are usable, because

27:23

ancient DNA is superfinicky. It degrades

27:25

with time. And like I said,

27:27

these were like 11,000 year old

27:29

specimens or more. Then they have

27:31

to patch together this DNA with

27:33

missing sequences from the genome, with

27:35

the wolf, like parts from the

27:37

wolf, again, which is a different

27:39

species, so not super compatible. And

27:41

then they have to edit the

27:44

current gray wolf genome to accept

27:46

these changes. Then. There's more steps.

27:48

They make a gene edited nucleus

27:50

and they inject this into a

27:52

gray wolf ovum or egg cell.

27:54

So we've been doing this for

27:56

a while, the injection. You've probably

27:58

seen this black and white image

28:00

of like a little needle going

28:02

into an egg. This is kind

28:04

of from the dolly, the sheep

28:07

ages. We're quite good at this

28:09

now. Still a lot of work.

28:11

More steps are coming. They produced

28:13

45 of these ova cells and

28:15

they developed them into embryos in

28:17

the lab. That sounds like not

28:19

a lot of work. It is

28:21

an incredible amount of work. Then

28:23

they took three, I believe, of

28:25

these embryos and inserted them into

28:27

the uteri of the surrogate dogs.

28:30

I was concerned about this because

28:32

usually with things like cloning you

28:34

get a lot of stillbirths and

28:36

miscarriages, but they said there were

28:38

none according to what they said

28:40

to the reporters. They also adopted

28:42

the dogs back out to a

28:44

shelter after this, which seems really

28:46

irresponsible to me, but anyway. And

28:48

the pups were born by C-section.

28:50

So that's the whole list of

28:53

how much work was put into

28:55

this for basically a PR stunt.

28:57

And I don't quite, I mean,

28:59

it made them a ton of

29:01

money. Like they're worth $10 billion.

29:03

So I guess that's why. But

29:05

there's one. more to it. That

29:07

could be enough. It does seem

29:09

like they want to do actual

29:11

science, that they're doing actual science

29:13

here, and then they're elevating it

29:16

in the public mind beyond what

29:18

they've actually done, and maybe that's

29:20

in order to raise more money,

29:22

which, you know, could be meant

29:24

to help them to make even

29:26

better strides in this. Yeah, and

29:28

I think that's... Like that's the

29:30

part they should be talking about

29:32

is like this is cool science

29:34

and like gene editing saves people's

29:36

lives and like advancing gene editing

29:39

is a worthy cause but it

29:41

feels so tone deaf in the

29:43

current circumstance. Like why wouldn't you

29:45

use this kind of work to

29:47

save currently endangered species which is

29:49

a part of what they say

29:51

they do but. For example, the

29:53

black-footed ferret, for example, if you've

29:55

heard about that, has 300 remaining

29:57

individuals in the wild. This one

29:59

has been cloned before, why not,

30:02

you know, help out with this

30:04

population? Because black-footed ferret doesn't have

30:06

as good as CEO as dire

30:08

wolf, that's why. Exactly. And there's

30:10

even endangered wolves like the red

30:12

wolves that we could save, but

30:14

I think it's just not as

30:16

flashy as a new story. I

30:18

do want to mention something and

30:20

see if you can guess. So

30:22

before we wrap up, did you

30:25

notice anything missing from this supposed

30:27

great breakthrough in science? Uh, I'm

30:29

gonna kick myself for not noticing,

30:31

but it sounds like they did

30:33

the science. They just claimed, they

30:35

just exaggerated the claim in the

30:37

end. How do we know that

30:39

they did the science? Oh, other

30:41

than the puppies there. Okay, so

30:43

so they published all of this,

30:45

right? I don't know. So there's

30:48

no peer review, there's no raw

30:50

data, and there's no published data.

30:52

I'm sure, maybe it'll come out,

30:54

I don't know. They don't really

30:56

favor this. And all the ethics

30:58

of side of like all of

31:00

this. One of the big issues

31:02

for me is that this is

31:04

not peer reviewed. Scientists, you know,

31:06

working on peer review with their

31:08

peers, sharing data, confirming findings, replicating

31:11

results, that is how you make

31:13

up the basics of science. That's

31:15

why we have a lot of

31:17

trust in scientists, because they're all

31:19

working together to make sure that

31:21

this is real. If we don't

31:23

do that, we run the risk

31:25

of having more things like vaporware

31:27

wolves. So that part, I think.

31:29

should be highlighted. Yeah, if this

31:31

is not published in peer-reviewed, then

31:34

it starts to become just a

31:36

cash grab in my mind. Yeah,

31:38

which so far it is because

31:40

I have not seen the publication.

31:42

Well, if anybody does, send it

31:44

to us feedback at daily tech

31:46

news show.com. We'd love to see

31:48

that as well. Dr. Nikki, thanks

31:50

so much. Thanks for having me,

31:52

Tom. See you next time they

31:54

come out with, I don't know,

31:57

a dodo, maybe. Ryan

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33:12

end every episode of D10S with some

33:14

shared wisdom. Thank you for your shared

33:16

wisdom. Jim Vido has a question. So

33:19

Jim Vido asked in discord, I was

33:21

wondering, when I get text spammed in

33:23

a group text, should I reply that

33:26

this is a spam message to help

33:28

the other recipients or go directly for

33:30

the spam button not letting the spamer

33:32

ever know I read the message? Oh

33:35

boy. Okay, I'm sure, like, let's both

33:37

answer this. I already know my answer.

33:39

My answer is flag and immediately move

33:42

on. Like, and I totally understand wanting

33:44

to save other people, but you put

33:46

yourself in more risk when you do

33:49

that. And I think in that scenario,

33:51

you just, you have to do what's,

33:53

what's safest for you. I, I 100%

33:56

agree. And I, I, I really get

33:58

it like you really like. I

34:00

totally get it, but I also

34:02

agree. You actually give them more

34:04

information when you respond, even if

34:06

you're trying to be helpful. So

34:08

that'll, yeah, I agree. Hopefully we

34:10

just get the message to everyone

34:12

that they should just ignore, spam, and

34:14

move on. I suppose if it's a

34:16

group text and somebody in the group

34:19

text actually does respond and buys into

34:21

it or whatever, then we would see

34:23

that and maybe then we send that

34:25

person a direct text and say, hey,

34:27

don't do that. that you know that

34:29

extra step but yeah I would the

34:31

more like you said the more signals

34:33

you give them the more they get

34:35

what they came for really at the end

34:37

of the day so what are you thinking

34:39

about got some insight into a story

34:41

share with us that feedback at daily tech

34:44

do show dot com Thank you

34:46

for sending that in Jim Video.

34:48

Thank you to Dr. Nikki for

34:50

contributing to today's show as well.

34:53

Thank you win. Always fun doing

34:55

the show with you. And thank

34:57

you for being along for Daily

34:59

Tech News Show. The show is

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made possible by our patrons at

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