Episode Transcript
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Manouche Zamorote. Some kids
0:55
are obsessed with trains, others
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love cooking. And then they're
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the ones who are really
1:01
into horses. I was kind of
1:04
born into it. This is
1:06
Catnod. When I was two
1:08
years old, I actually learned how
1:10
to can't or on a horse
1:12
for the first time. By
1:14
the age of six, Kat
1:16
knew what she wanted to be
1:19
when she grew up. I
1:21
decided I want to go
1:23
to the Olympics for horseback riding
1:25
and represent Canada and my entire
1:27
life has kind of been centered
1:30
around that goal of being an
1:32
Olympic horseback rider. How much of
1:34
your life, your daily life did
1:36
it take up? Like what was
1:38
the whole regimen? Is there a
1:40
percent higher than 100? In her
1:42
20s, Cat was on track to
1:44
make it to the 2016 Olympics
1:46
in a sport called Three Day
1:48
Aventing. So it's got three phases
1:50
over three days. So the dressage
1:52
is kind of like dancing on
1:55
horses. You have like a routine
1:57
you do at certain places in
1:59
a test. The second phase is
2:01
called show jumping. That's what you
2:03
see on TV where they jump
2:05
the big jumps with the rails
2:07
that fall down. And then the
2:09
third phase is cross country. It's
2:12
where you're going over big solid
2:14
jumps that if you hit the
2:16
jumps, you fall down, not the
2:18
jump. They'll have like a six
2:20
foot wide ditch with a wall
2:22
in the back and you have
2:24
to jump all of it at
2:27
the same time or like a
2:29
seven, eight foot drop into water.
2:31
And if you make a mistake,
2:33
there's no forgiving. So there she
2:35
was at the Olympic qualifiers. She
2:37
and her horse sailed through the
2:39
first two events, no problem. I
2:42
was actually in first place heading
2:44
into cross-country, which was my strongest
2:46
phase, and it was my 25th
2:48
birthday. And I was super excited.
2:50
We headed to the start box
2:52
to do our two-minute countdown. There's
2:54
nothing that gets me more excited
2:56
than the last 10 seconds before
2:59
you get to go. And we
3:01
set out on course, my horse
3:03
Jackson and I, the entire course
3:05
flew by in perfect jumps. There
3:07
was not even a misstep to
3:09
a single fence. And we headed
3:11
to home to our very last
3:14
jump when my horse Jackson and
3:16
I saw a completely different distance
3:18
from each other to the fence.
3:20
And he's enormous, so he's 17-3
3:22
hands, which is just under six
3:24
feet where his back is. and
3:26
the last fence was a big
3:29
upright table and he caught the
3:31
front edge of it with his
3:33
knees and we had what's called
3:35
a rotational fall. What I can
3:37
equivalent is to a summer salt
3:39
in the air and he landed
3:41
on top of me on the
3:43
other side and slid 10 feet
3:46
with him on top of me.
3:48
He weighs about 1500 pounds. I
3:50
lost consciousness or a very brief
3:52
amount of time. I
3:54
remember kind of coming back to
3:56
and he'd jumped off of me
3:58
and ran off and... people rushed
4:00
over and they're trying to hold
4:02
you down so you don't get
4:05
up just in case you have
4:07
very severe injuries And all I
4:09
could do is try to flail
4:11
and figure out where my horse
4:13
was and that was my main
4:15
concern is where is he okay?
4:17
Shock kind of takes over an
4:19
adrenaline and adrenaline and then I
4:21
was actually airlifted to the hospital
4:23
in Seattle and from there it
4:25
was a definitely whirlwind a few
4:27
days What in the end did
4:29
they figure out had had happened
4:31
to you? What was damaged in
4:33
your body? So I had broken
4:35
the transverse processes, the wings off
4:37
both sides of my out two,
4:39
three, and four, vertebra in my
4:42
back. I was told if you're
4:44
going to break your back that
4:46
the way that I broke it
4:48
was the best way possible. So
4:50
that's like I guess good to
4:52
do some comfort. When you were
4:54
leaving the hospital, what did your
4:56
doctors tell you to expect? Yeah,
4:58
so they said that I was
5:00
going to be about four months
5:02
till I felt more normalized, like
5:04
I was going to be able
5:06
to do more activity, more walking,
5:08
even think about getting back on
5:10
a horse. It was tough. The
5:12
pain level was something I'd never
5:14
really experienced before. I would hit
5:16
like an unmanageable level of pain
5:19
every single day. When I give
5:21
you the pain scale, like I
5:23
would hit a 10 out of
5:25
10 at some point every day.
5:27
So what keeps you going? Because
5:29
you thought, okay, well, this is
5:31
just temporary. I need to get
5:33
through this, you know, initial period
5:35
and then I'm going to feel
5:37
better. Is that what you were
5:39
thinking? Yeah. So being four months,
5:41
like four months in hindsight is
5:43
not that long. I was just
5:45
trying to grind it out to
5:47
get back to training. I knew
5:49
there was still some qualifiers left
5:51
in the season, so if I
5:53
could recover and get back quick
5:56
enough, I could try to still
5:58
make a run for the... you
6:00
know, being an Olympic athlete
6:02
and I had really
6:04
just expected my body to
6:06
bounce back. When did you
6:08
start to realize that things
6:10
were not going back
6:13
to quote-unquote normal or
6:15
before times? Yeah, so about
6:17
the four-month mark, I was
6:19
really not feeling any better,
6:21
but they said four months, so
6:24
four months to the day I
6:26
got on my horse and the first
6:28
step he took. was instantly
6:31
10 out of 10 pain. I was
6:33
nauseous from pain and I almost
6:35
fell off just because I couldn't
6:38
even breathe. And I knew that there
6:40
was more going on. I knew that
6:42
something had been missed. I knew
6:44
that whatever was happening had not
6:47
healed the way that they were
6:49
kind of expecting it to and
6:51
I had to get instantly off
6:54
and I was crushed. They actually
6:56
found out that my pelvis
6:59
was dislocated and I was
7:01
having stability issues and that's
7:03
actually why I had so much pain
7:06
and I got to the hospital in
7:08
Vancouver and Waited for over
7:10
four hours in a waiting room
7:12
on a hard chair with a
7:14
back that You're thinking any moment
7:17
like what if I sneeze and
7:19
now I'm paralyzed so it was
7:21
quite a scary wait not knowing
7:23
What level of stability would happen
7:25
if I shifted the wrong way?
7:27
Am I going to make it
7:30
worse? When they finally called me
7:32
in to do the check with
7:34
the doctor, I handed him my
7:36
requisition and he didn't even look
7:39
at it. He put it down.
7:41
He didn't examine me.
7:43
He didn't ask me a
7:45
single question about my pain,
7:47
about what I was experiencing,
7:49
about what my doctor had
7:51
said. He lived in and
7:53
he said, what drugs do
7:55
you want? And I was like, no,
7:58
no, I need help. He said, I'm. so
8:00
you can take the drugs
8:02
or you can leave. Yikes.
8:04
And what did you say?
8:06
I left. I wasn't there
8:08
for narcotics. I was there
8:10
for help and support and
8:12
I got none of that
8:14
and it was a really
8:16
disappointing experience and for me
8:18
I'd been kind of holding
8:20
out hope that I was
8:22
going to heal physically and
8:24
to be that dismissed. I'd
8:26
lost hope that day. That
8:28
day was actually the first
8:30
day of the downward spiral
8:32
for me mentally. And a
8:34
couple months after that experience,
8:37
I kind of hit my
8:39
rock bottom of where I
8:41
just couldn't fight through this
8:43
anymore. When you say you
8:45
hit rock bottom, what do
8:47
you mean? I slid into
8:49
like depression quite quickly. And
8:51
I've actually never had experienced
8:53
anything like depression before. And
8:55
until you know, you don't
8:57
know. The pain was intolerable.
8:59
I would dislocate my pelvis
9:01
and fall and be kind
9:03
of stranded. I limped every
9:05
single day. Some days my
9:07
leg almost felt like a
9:09
peg leg, like I had
9:11
to drag it behind me.
9:13
Were you getting treatment at
9:15
that point? I had stopped.
9:17
I had kind of given
9:19
up hope because I had
9:22
tried so many things previous.
9:24
and nothing had really caused
9:26
any significant relief or progression
9:28
of my symptoms. And I've
9:30
been told by several doctors
9:32
that like there's a real
9:34
chance that this is just
9:36
physically your life and you'll
9:38
have to acclimate to it.
9:40
You won't be able to
9:42
walk normally, you will limp,
9:44
you will be in high
9:46
degrees of pain, you will
9:48
have instability in your pelvis
9:50
for life, this is your
9:52
life now. Yeah, it's like
9:54
at 25 when you have
9:56
so much of your life
9:58
ahead of you, it's really
10:00
hard to justify spending the
10:02
rest of your life that
10:04
way. When you're In that
10:06
kind of depth of the
10:09
darkness, you can't see past
10:11
the darkness. You can't see
10:13
little light at the end
10:15
of the time. Well, you're
10:17
not looking for hope. You
10:19
are just alone in the
10:21
dark. In a single moment,
10:23
Cat Nod's life was taken
10:25
over by pain. First acute,
10:27
then chronic. She felt alone,
10:29
confused, and hopeless. Like most
10:31
of us, she'd heard about
10:33
the dangers of opioids. Roughly
10:35
80,000 Americans a year are
10:37
dying from opioid overdoses. And
10:39
the opioid epidemic has morphed
10:41
over the years well beyond
10:43
a pain pill problem. But
10:45
we don't hear much about
10:47
other options for coping with
10:49
pain. So what do we
10:51
need to know about the
10:53
next chapter in Pain Relief?
10:56
Today on the show... new
10:58
understandings about how the brain
11:00
interprets pain and what we
11:02
can do to manage pain
11:04
in the short and long
11:06
term. Later in the show,
11:08
we'll hear more from Catnod.
11:10
But first, please meet pain
11:12
expert Dr. Amy Baxter. When
11:14
you live with chronic pain,
11:16
it is really easy for
11:18
it to take over and
11:20
define who you are. Amy
11:22
says that in the 30
11:24
years she's been studying and
11:26
developing methods to treat pain
11:28
She has heard all sorts
11:30
of preconceived notions related to
11:32
it Talking about pain is
11:34
so nuanced and loaded in
11:36
our society Because we're supposed
11:38
to be tough and we're
11:41
supposed to deal with pain
11:43
And also because we are
11:45
a society that fears aging,
11:47
and pain means decrepitude, never
11:49
doing the things that make
11:51
you you, and even a
11:53
little bit of pain carries
11:55
extra meaning, because it means
11:57
that both you're weak and
11:59
you may not get over
12:01
being weak. Amy suggests. we
12:03
put all those judgments aside
12:05
because pain affects everyone differently.
12:07
And as we'll explain later,
12:09
how the brain processes pain
12:11
can be confusing. But, she
12:13
says, we need to remember
12:15
one key thing about it. Pain
12:17
is a survival system that serves
12:20
us, and when it ceases to
12:22
serve us, then we can choose
12:25
to ignore it. We don't have
12:27
to let it rule us.
12:29
That is the most important
12:31
paradigm shift for dealing with
12:34
both acute pain and chronic
12:36
pain. But the thing about pain
12:38
is there isn't one answer.
12:41
It is a giant different
12:43
complex beast to every different
12:45
person. And so we in
12:47
the medical profession are used
12:50
to one right answer and
12:52
treating it as one thing.
12:54
It just isn't. In
12:57
a minute, Amy talks us through
12:59
the past, present, and future
13:01
of pain management. On the
13:04
show today, rethinking ideas about
13:06
pain. I'm Manusha Zamorote, and
13:08
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NPR. I'm Manush Zamorodi. On
16:18
the show today, pain relief.
16:20
How to rethink and deal
16:22
with physical pain. And a
16:24
warning, some of this episode
16:26
touches on addiction and a
16:28
drug overdose. We were just
16:30
talking to physician and pain
16:32
expert Amy Baxter. Amy says
16:35
our ideas about how to
16:37
treat pain often start at
16:39
a young age. We
16:41
start early with children saying, oh you bumped
16:43
your this, oh you have a fever, let
16:45
me give you a pill. We
16:47
really are telling each other that a
16:49
pill is the way to solve a
16:52
problem and that isn't going to work
16:54
when that is part of your survival system. You
16:56
can't shut it down with a pill. Amy
16:59
believes that we need to teach
17:01
or be taught to see pain
17:03
as a messenger and listen closely
17:05
to what it tells us rather
17:07
than fear it. But
17:09
this is not what Amy
17:11
learned back in medical school 30
17:13
years ago. In medical school,
17:16
pain was a lot less important than
17:18
diagnosing and treating whatever was causing
17:20
it. We didn't actually talk much
17:22
about what the nature of pain
17:24
was. It was this amorphous bad
17:26
thing. But as a doctor, it's
17:28
kind of like pain happens. Amy
17:31
did her residency and she specialized
17:34
in pediatric medicine. And as
17:36
a young budding physician, she found
17:38
this approach hard to swallow.
17:40
So one of the hardest things
17:42
about being a doctor is
17:44
quelling down your empathy because it
17:46
can get in the way
17:49
of the diagnosis or the management
17:51
that you need to be
17:53
responsible for making sure happens. But
17:55
then the theory of putting a
17:58
side pain to get a diagnosis faded
18:00
away. It was the mid-90s
18:02
and a new approach was
18:04
being offered by pharmaceutical companies.
18:06
Doctors could be pain advocates
18:09
for their patients, thanks to
18:11
a new line of pain
18:13
relief medications. That
18:15
was when I first heard
18:17
the concept of pain-free. At
18:20
the time it sounds great, you know,
18:22
why wouldn't you want that for your
18:24
patients? We even had buttons that said
18:26
pain-free on them, and all of us
18:28
who were pain advocates wore them on
18:31
our white coats. You know, it's like,
18:33
pain-free, I am going to get you
18:35
to pain-free, and what's not the love
18:37
about being pain-free? Amy remembers the
18:40
first time she got the opioid
18:42
pitch. Here she is on the TED
18:44
stage. The only pain lecture I
18:46
remember from the 90s was
18:48
in a dark room like
18:50
this, after being awake for
18:52
30 hours and hungry, finding
18:54
out our noon lecture was
18:57
sponsored by OxyContin. We got
18:59
pens, we got great lasagna,
19:01
and they had very cool
19:03
slides that showed pain stopped
19:05
by opioids. And we learned
19:08
that home opioids aren't addictive,
19:10
and if you stay ahead
19:12
of pain, you can keep
19:14
your patients pain free. But
19:16
we've all heard how the story of
19:18
opioids and addiction has gone.
19:21
Patients became customers, and
19:23
so you were supposed to respond
19:25
to what a patient wanted, and
19:27
if they had pain, you needed
19:29
to both measure it and address
19:31
it. And I realized that part
19:33
of what Purdue did was suborn
19:35
the message of care and make
19:37
it a message of a prescription.
19:40
You know, I care about you, I'm going to
19:42
give you the good stuff, I care about
19:44
you, I am going to make it so
19:46
you don't hurt it all." And beyond
19:48
the obviously egregious marketing, I
19:50
think it was framing pain-free
19:53
as the goal that has
19:55
destroyed countless lives. My friend's
19:57
son, Christopher, started having...
19:59
severe abdominal pain during this
20:02
no-pane era. Eventually, he was diagnosed
20:04
with a colon disease and had
20:06
surgery his senior year. They sent
20:09
Christopher home with 90 oxygen and
20:11
then 90 more, and then as
20:13
the pain started getting faster and
20:16
faster, uncontrolled pain is terrifying. So
20:18
when his ran out and his
20:21
friend's medicine cabinets ran out, Christopher
20:23
tried heroin. And Christopher Wolfe lost
20:25
his battle with substance use at
20:28
age 32. Christopher got 90 OxyContin
20:30
for a stomach surgery. We would
20:32
never do that now, but I
20:35
was in the generation that if
20:37
I had taken care of Christopher,
20:40
I would have written for that.
20:42
It's just what you did. Hmm.
20:44
Doctors... trained when I was in
20:47
the 90s, believed that there was
20:49
no amount of pills you could
20:51
give someone that would cause a
20:54
problem if they had, quote, real
20:56
pain. So it turned out that
20:58
the promise that OxyContin was less
21:01
addictive wasn't true. Purdue Pharma pleaded
21:03
guilty to federal crimes for false
21:06
marketing. Yeah. But here we are
21:08
with researchers saying that more than
21:10
two million Americans now have some
21:13
degree of opioid addiction. Can you
21:15
just explain what these drugs do?
21:17
What is it that happens in
21:20
our brain that makes us feel
21:22
better? Yeah. At least at first.
21:25
Yeah. What we didn't know is
21:27
that taking opioids actually increases your
21:29
sensitivity to pain because you're used
21:32
to feeling so rewarded that you
21:34
don't notice it. So, dopamine, which
21:36
is what opioids... address, dopamine makes
21:39
you feel like you're winning and
21:41
you're so rewarded that you don't
21:43
care if you're feeling pain because
21:46
you just feel great. And if
21:48
it's a really excruciating pain, opioids
21:51
are the best thing we found.
21:53
to hardcore trigger the dopamine response
21:55
that makes you feel rewarded. So
21:58
it's great for the first couple
22:00
of days and the first 24
22:02
hours after a burn or trauma,
22:05
the more opioids, the less post-traumatic
22:07
stress, etc. But because your brain
22:10
is constantly adapting, what ends up
22:12
happening is after about 72 hours,
22:14
you're New receptors, you're dopamine, I
22:17
feel great receptors, have actually hidden
22:19
inside cells. And that's about when
22:21
you go home and you're taking
22:24
an oral pill that is not
22:26
nearly as potent as what you
22:28
were getting through your IV. And
22:31
now you're just getting the risk
22:33
in the side effects. What is
22:36
actually happening that some of us
22:38
feel awful on percocet or other
22:40
narcotic drugs and other people can't
22:43
get enough of them? If you've
22:45
ever been in a Mexican restaurant
22:47
and somebody at your table says,
22:50
I cannot abide cilantro, it tastes
22:52
like soap. And you're like, are
22:55
you kidding me? cilantro is great.
22:57
That's what's going on with opioids.
22:59
A percentage of the population get
23:02
opioids and their taste of it
23:04
is completely different. So they don't
23:06
process dopamine in the same way.
23:09
They don't get as much. Great
23:11
taste from the kind of dopamine
23:13
mastery or novelty or you know
23:16
excitement or winning They're not getting
23:18
that as much when they get
23:21
an opioid. Oh, yeah, they get
23:23
it. Huh and that can be
23:25
exacerbated by a bad situation So
23:28
the right circumstances with the wrong
23:30
genes is a dangerous combo. Yes,
23:32
even though even the good circumstance
23:35
with the wrong genes three days
23:37
or more is when the risk
23:40
starts increasing of being dependent So
23:42
it's not necessarily the... no matter
23:44
how it makes you feel whether
23:47
you love it or hate it,
23:49
regarding pain, it doesn't actually necessarily
23:51
do the job that we've thought
23:54
it? Does? Yeah, I think this
23:56
really gets to the nature of
23:58
pain. What is the job that
24:01
we want opioids to do and
24:03
what exactly is pain? As I
24:06
started unpacking the nature of what
24:08
Purdue Pharma had taught me, I
24:10
realized I believed and I think
24:13
many believed that pain was a
24:15
switch on off and you don't
24:17
want to habit. But pain isn't
24:20
a switch. It's not as magical
24:22
as if you are in pain
24:25
and then all of a sudden
24:27
the pain goes away. Amy
24:30
now believes that the best
24:32
definition of pain comes from
24:35
the international association of the
24:37
study of pain. They say
24:39
it's an unpleasant sensory and
24:41
emotional experience that is associated
24:43
with actual or potential tissue
24:45
damage. This idea of pain
24:47
as a sensory and emotional
24:49
experience got Amy thinking about
24:51
where she could begin to
24:53
try different tactics to mitigate
24:55
pain. She decided to go
24:57
back to a place she
24:59
knew well, a place where
25:01
many of us first experience
25:03
acute pain, the pediatrician's office.
25:05
I noticed that other doctors
25:07
weren't addressing needle pain for
25:09
kids. Like getting a vaccine
25:11
like my daughter still screams
25:13
and she's a teenager. Yeah,
25:15
well, here's the deal. You
25:17
and I. got six injections
25:19
and we got them before
25:21
we were two and we
25:23
don't remember and we think
25:25
we were really cool because
25:27
we don't mind needles. But
25:29
yes, starting. So true. I
25:32
know. Well, so here's the
25:34
thing. I started looking back
25:36
at the history of vaccines
25:38
and I was like, whoa,
25:40
I had no idea. We
25:42
have 36 separate shots now.
25:44
And I realized this when
25:46
my four-year-old had his vaccines,
25:48
and he had such an
25:50
awful experience that afterwards he
25:52
threw up, and I was
25:54
like, if he gets old
25:56
enough to drive himself to
25:58
the doctor, he won't. the
26:00
soft tissue of the arm,
26:02
the sensation goes to the
26:04
spine, then the brain. And
26:06
the brain remembers that
26:08
feeling. So if we
26:10
anticipate fear feeling that
26:12
sensation again, that memory
26:14
can make every future
26:16
shot seem so much
26:19
worse. Pain is this
26:21
contextual response to whether
26:23
you're safe or not. When
26:25
you're afraid, you're... Neurotransmitters
26:29
that say danger are elevated
26:31
and your memories of fear
26:34
elevated and that fear increases
26:36
your perception of pain and
26:39
certainly when you're in pain
26:41
and you're afraid of not
26:43
being able to get relief
26:46
that fear lays down tracks
26:48
in your brain I mean all
26:51
of these things happen that
26:53
increases your perception of pain.
26:55
How to do that lesson
26:57
the initial sensation. Twenty
27:00
years ago, I just wanted to
27:02
have a fast cure for needle pain
27:04
for IV access and my kids'
27:06
shots. I was driving home one
27:08
night after a graveyard shift,
27:10
and my hands were vibrating on
27:13
the steering wheel because we needed
27:15
to get the tires balanced. I
27:17
was ignoring that to think about
27:19
pain, and when I got home and
27:22
reached for the door in my house, my
27:24
hand was numb. Vibration.
27:27
So I burst in, my Boy
27:29
Scout husband grabbed some frozen
27:31
peas, and we had ourselves
27:34
a genuine Eureka moment. We're
27:36
cold, and vibration blocked pain.
27:39
Over the next decade, I found
27:41
the right frequency to block
27:43
pain, I got a grant,
27:45
and I created Buzzy, which
27:47
is vibration plus ice in
27:49
a B-shape, and you put it
27:52
on your arm when you're
27:54
getting an injection, and to
27:56
date... 45 million needle procedures
27:58
had decreased pain and and
28:00
over 80 randomized controlled trials
28:02
independently all around the world
28:04
have been published. So the
28:07
reason that vibration decreases pain
28:09
is because the physiology of
28:11
the nerves of light touch,
28:13
pressure, stretching, and motion all
28:15
race pain to the spine.
28:18
We now know that motion
28:20
is what's most effective at
28:22
shutting the sharp pain. This
28:24
is called gait control and
28:27
the exact right frequency of
28:29
vibration triggers the nerves that
28:31
decrease pain. So if you
28:33
burn your finger and you
28:36
stick it under cold water,
28:38
instantly the burn feels better.
28:40
If you've ever tried putting
28:42
it just in ice water
28:44
but not moving it, you
28:47
will find the cold itself
28:49
doesn't do it. You have
28:51
to actually stir your finger
28:53
around to make it work.
28:56
The movement's the critical part,
28:58
the cold helps. Well, too...
29:00
manufacture this sensation of movement,
29:02
I stumbled upon vibration. The
29:05
physiology of ice is different.
29:07
So the cold goes up
29:09
to the brain where the
29:11
conductor goes obnoxious but not
29:13
dangerous, I will decrease sensations
29:16
coming from everywhere. And it
29:18
decreases pain everywhere. If a
29:20
child was so freaked out
29:22
from previous experiences, that even
29:25
the swab hurt. Physiology
29:27
wasn't as helpful. So we
29:29
added distraction, like a monkey
29:31
poster, and what we discovered
29:34
was combining counting plus making
29:36
a decision, cut pain in
29:38
half. So for example, how
29:40
many monkeys are actually touching
29:43
the bed activates the decision
29:45
switchboard? I know what you
29:47
guys are doing. All right,
29:49
it's five. The
29:53
biggest tack, though, is understanding
29:55
why distraction works. And now,
29:57
through functional MRI, we can
29:59
actually see pain happen. And
30:02
it's not one place. Pain
30:04
is a symphony of connections
30:06
from the sensation area to
30:09
the conductor, to the decision
30:11
switchboard, and then to fear,
30:13
memory, meaning, control. So if
30:15
the decision switchboard is occupied
30:18
sorting monkeys, it can't notify
30:20
fear and meaning, and you
30:22
feel less pain. What you
30:25
... is mostly what you
30:27
expect to feel. So there
30:29
are so many different things
30:32
you can try, cold, vibration,
30:34
distraction, mind games. Yeah, you've
30:36
always got one other thing
30:38
to try, so it keeps
30:41
you from being afraid. A
30:43
big part of my pain
30:45
re-education came when I was
30:48
asked to do a talk
30:50
in Wisconsin for a child
30:52
life. conference. I'd been invited
30:54
to talk about different medications
30:57
for sedation because that was
30:59
my specialty and how to
31:01
deal with pain. And an
31:04
amazing woman who invited me,
31:06
Regina Yoakum, told me afterwards
31:08
from her wheelchair where she
31:10
had been since she was
31:13
young from juvenile arthritis. She
31:15
said, you know, I appreciate
31:17
knowing about these medicines, but
31:20
the thing is there's only
31:22
a finite number of medicines.
31:24
There are much larger number
31:27
of physical interventions and there
31:29
are so many. different ways
31:31
to activate your brain so
31:33
that you just don't mind
31:36
pain, that really what pain
31:38
management is for us, and
31:40
for her personally, is knowing
31:43
there's always another option. That
31:45
changed everything for me. Choosing
31:47
physiologic options that you can
31:49
layer that work for you,
31:52
decrease pain. Like... Heat cold
31:54
vibration, deep relaxation, acupuncture capsaic,
31:56
and exercise meditation. There's more.
31:59
Christopher probably had 10 of
32:01
these around. and just didn't
32:03
know it. Having control over
32:06
your options decreases pain, deep
32:08
breathing increases control, choosing what
32:10
to focus on increases control.
32:12
Fear and control are the
32:15
volume knobs for pain. Fear
32:17
controls so many of our
32:19
sensations, this shouldn't be unusual,
32:22
but we don't practice it
32:24
for pain. So if you're
32:26
home alone and you hear
32:28
a clunk, Your
32:31
hearing becomes hypersensitive. But when
32:33
you remember your kid's home
32:35
from college, your fear dials
32:38
down, and your brain overrides
32:40
it and says, don't worry
32:42
about it. St. Augustine called
32:45
pain the greatest of evil.
32:47
But if it is a
32:49
survival system, it cannot be
32:51
all evil. So instead, think
32:54
of pain as you're nagging,
32:56
safety obsessed. exaggerating friends who's
32:58
sometimes wrong. And it's okay
33:01
to ignore or override your
33:03
friend if you know that
33:05
you're safe. This takes practice.
33:07
On a flight that was
33:10
turbulent, I had an entire
33:12
cup of scalding hot coffee,
33:14
dumped straight on my ankle.
33:17
Electric jolt through my scalp,
33:20
I ripped off my sock,
33:22
it was already red, it
33:24
was going to blister, there
33:27
was no way I could
33:29
get my foot into that
33:32
little sink to get cold
33:34
water on it, and then
33:36
I remembered, physiology hack. I
33:39
had an open cold beer.
33:41
Medical grade cold beer went
33:43
on my ankle stat. I
33:46
had a vibrator in my
33:48
carryon because I would on
33:50
my ankle stat. and then
33:53
the pain kind. And pain
33:55
MacGyver, I was no longer
33:57
that concerned. Although
34:05
then I realized I'm that
34:07
guy with my barefoot sticking
34:09
out in the aisle on
34:11
a plane with a beer
34:13
on it. So that's dealing
34:16
with acute pain. But in
34:18
a minute, physician and pain
34:20
expert Amy Baxter explains more
34:22
about how all of these
34:24
methods can also help with
34:26
chronic pain. On the show
34:29
today, pain relief. I'm Anusha
34:31
Zamorote and you're listening to
34:33
the Ted Radio Hour from
34:35
NPR. Stay with us. This
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36:49
It's the TED Radio Hour from
36:51
NPR. I'm Manouch Zamorote. Today on
36:53
the show, we're looking into the
36:56
past, present, and future of how
36:58
we treat pain. We've been talking
37:00
to physician and pain expert Amy
37:03
Baxter. And as we heard, Amy
37:05
decided to research different ways to
37:07
relieve pain after working as a
37:10
physician throughout the opioid crisis and
37:12
seeing the lack of options given
37:14
to patients. Living pain-free, she says,
37:17
was a false promise made by
37:19
the pharmaceutical industry. But dealing with
37:21
chronic pain requires multiple strategies, especially
37:24
as we better understand what long-term
37:26
pain actually is. It's something of
37:28
a moving target as we get
37:31
better information from functional MRI. It
37:33
used to be that pain was
37:35
defined as acute until three months,
37:38
and then magically it became chronic.
37:40
My own personal opinion based on
37:42
the way the brain changes is
37:45
that probably it's more of a
37:47
72-hour thing. The thing is that
37:49
the body adapts really really quickly
37:52
to what's going on and starts
37:54
making different coping mechanisms. those are
37:56
probably the better definition of acute
37:58
versus chronic pain. And we've moved
38:01
the goalpost from three months to
38:03
one month, but I think that
38:05
probably the scientific literature is going
38:08
to move it even closer to
38:10
the event of the tissue damage
38:12
in the next decade or so.
38:15
If someone is listening and they're
38:17
thinking, okay, just tell me what
38:19
to do if I am going
38:22
in for a procedure and I
38:24
want to deal with acute post-op
38:26
pain. and then what I can
38:29
do for chronic pain. One thing
38:31
that's important, and I even
38:33
this morning got a letter from
38:36
somebody who is outraged that I
38:38
wanted to take people's opioids away,
38:40
I do not mind if people
38:42
who are chronically managed with opioids
38:44
have the same dose from now
38:46
until the rest of their lives,
38:48
because they rarely overdose and they
38:50
rarely increase the doses. That is
38:52
not where the problem is. My
38:55
real mission is to stop giving...
38:57
pills out after surgery. By not
38:59
having other pain options, we
39:01
leave doctors with no choice
39:03
but to give opioids at
39:06
home after a surgery because
39:08
they want to help. But
39:10
it's about 6% of every
39:12
surgery have people who are
39:14
still in opioids 90 days
39:16
later who weren't before. is
39:19
so clearly consistent despite the
39:21
caliber of the surgery, and
39:23
we should make people aware
39:25
of this before they take
39:27
a medicine, that they may
39:29
be better off with ibuprofen
39:31
or an ice pack or
39:33
vibration or having a whole bunch
39:35
of friends over. Power of our
39:37
pain isn't always pretty, but it
39:40
is possible, and it is
39:42
absolutely critical. So what do
39:44
we do? Well, in my dream
39:47
world, we have health care
39:49
systems. pay for options and coaching,
39:51
and we quit giving double-digit prescriptions
39:54
for opioids for home recovery. In
39:56
the real world, 80,000 people died
39:58
in the US. last year from
40:01
opioid overdoses, and 80% of substance
40:03
use disorder starts with a pill
40:05
prescribed for pain, usually taken from
40:07
your friend's medicine cabinet. You all
40:10
now know to throw away the
40:12
opioids and your medicine cabinet. You
40:14
now know that there are options
40:17
you can use to decrease pain,
40:19
and you know that pain-free should
40:21
be ditched for more comfortable. And
40:23
whether you Dump skeleton coffee or
40:26
pain wakes you and exhausts you
40:28
every day. Options that are in
40:30
your control can allow you to
40:32
reframe pain. So one of the
40:35
options for dealing with acute pain
40:37
is a tool that you created
40:39
called Buzzy. It's for kids, it
40:41
both cools and vibrates, it looks
40:44
like a little B, and it
40:46
has FDA approval. But what about,
40:48
say, a grown-up with chronic back
40:50
pain? Do you have tools for
40:53
that, Amy? So I will say
40:55
that low back pain is the
40:57
number one source of disability worldwide.
40:59
It is the number one reason
41:02
people go from acute opioids to
41:04
chronic. And... What we know about
41:06
low back pain now is the
41:08
same with a lot of injuries
41:11
that go on to become chronic.
41:13
The problem is not the original
41:15
insult. The problem is that the
41:17
small muscles that are holding you
41:20
still so you don't increase pain,
41:22
those muscles aren't designed to have
41:24
that much load. They try to
41:26
rise to the challenge and they
41:29
don't have the plumbing. So they
41:31
lose the blood supply. They have
41:33
lactic acid and hurt like you've
41:35
worked out too hard. And over
41:38
time, they get fatty changes that
41:40
further decrease the blood supply and
41:42
then they start getting shrunken. And
41:45
so I started reading and I
41:47
started playing around with different frequencies.
41:49
What we do now is we
41:51
have three different frequencies that decreases
41:54
fatty changes and then we played
41:56
around. with amplitude so you can
41:58
get it to penetrate different depths
42:00
of tissue. And the final pivotal
42:03
trial will be done with the
42:05
chronic patients on June 30th. What
42:07
we are hoping is that we
42:09
will have not just a reduction
42:12
in pain, but actually reduction in
42:14
opioid use. But it's not ever
42:16
going to be enough to have
42:18
one thing. people need to realize
42:21
that a little bit of magnesium
42:23
is perhaps going to shave 10%
42:25
maybe 30% off of how much
42:27
pain they perceive, but it's going
42:30
to take a few days to
42:32
kick in, a little bit of
42:34
exercise, just bending over and lifting
42:36
up 10 times a day, and
42:39
then gradually getting to 20 times
42:41
a day, and then doing it
42:43
with a tiny weight. That I
42:45
have heard from people who have
42:48
overcome their back pain. And they're
42:50
doing the same thing we're trying
42:52
to do. They're rehabilitating those little
42:54
muscles, but it's very slow. I
42:57
wish people with chronic pain knew
42:59
it was okay not to think
43:01
that they're going to find one
43:03
thing that's going to fix their
43:06
pain. Oh, but Amy, it would
43:08
be so nice if there was
43:10
like this one magic thing that
43:13
just took care of it. What
43:15
you're describing, that's like taking on
43:17
a part-time job. Yeah, it's a
43:19
part-time job. It's a remodel of
43:22
your brain. And nobody in it
43:24
wants to hear that if they
43:26
did a whole bunch of things
43:28
every day for six months, they
43:31
would feel a lot better, because
43:33
it's really hard to get up
43:35
the energy to even do too.
43:37
You are reminding me of the
43:40
story you told in your talk
43:42
about your friend's son, Christopher, who
43:44
ended up addicted to opioids after
43:46
major surgery and later overdosed. What
43:49
would you have done for Christopher
43:51
now? Oh, wow. Well... If you
43:53
ask what I would do for
43:55
Christopher now, Cammy Wolf, Christopher's mom,
43:58
is actually doing it for people
44:00
at Grady Hospital in Atlanta who
44:02
have trauma. They're teaching them about
44:04
how to go home without opioids.
44:07
I thought, how can I warn
44:09
people? How can we stop this
44:11
in hospitals? I didn't even think
44:13
one second to ask the doctor
44:16
about the medication he was being
44:18
given. But when you're on OxyContin,
44:20
you know, you can become addicted
44:22
with one prescription. And of course,
44:25
I had no idea. None. This
44:27
is Christopher's mom and Amy Baxter's
44:29
friend, Kami Wolf Rice. She vividly
44:31
remembers bringing Christopher home from the
44:34
hospital. He was going home with
44:36
a hole in his stomach and
44:38
a bag, and he needed psychological
44:41
counseling, right, to deal with that,
44:43
for a 17-year-old boy, right, a
44:45
senior year in high school. They
44:47
didn't prep us for what we
44:50
were going home with, and not
44:52
one single solitary word about any
44:54
risk involved at all. Zero. Christopher,
44:56
you know, his dream was to
44:59
be a Navy SEAL. He was
45:01
very disciplined. He was an AP
45:03
student. Just super book smart is
45:05
the way I would describe, but
45:08
a hugger. Years passed and he
45:10
didn't stop taking the pills. So
45:12
he was just constantly on the
45:14
opioids and still managed to go
45:17
to college, graduated college. But then
45:19
he's the one that came to
45:21
me and said, Mom, I have
45:23
got a problem. I need this
45:26
medicine, just like you need air
45:28
to breathe. He fought it for
45:30
14 plus years. I'm talking multiple
45:32
rehabs. But when it hijacks your
45:35
brain, you trigger things happen and
45:37
you relapse. And he kept thinking
45:39
he was failing us. He was
45:41
failing himself, which of course... depression
45:44
sets in and you could have
45:46
never in a million years would
45:48
have I ever thought that Christopher
45:50
would have done heroin but he
45:53
couldn't get the pills and so
45:55
he had to go to the
45:57
street. He
46:00
overdosed in 2016. And it
46:02
literally took me two years
46:04
to even talk to my
46:06
family because of the stigma
46:08
that we have in this
46:10
country. As sadly as it
46:12
sounds, I didn't want him
46:14
to have a disrespectful death.
46:16
I didn't want people to
46:18
think of him horribly because
46:20
he was such a wonderful
46:22
person. So I think there
46:24
was enormous guilt that I
46:26
was feeling that I failed
46:29
as a parent. I failed
46:31
as a mother. You know,
46:33
I failed as a mother.
46:35
But then I realized that
46:37
silence is deadly. And we
46:39
need to be able to
46:41
speak out because if everybody
46:43
was honest about it, everyone
46:45
knows somebody that's suffering with
46:47
addiction. Everybody. That's when
46:49
Cammy came up with an idea
46:51
to give patients someone to guide
46:53
them through the shock of dealing
46:56
with pain, a kind of pain
46:58
coach that she called a life
47:00
care specialist. We use coaches for
47:02
everything in our society, except for
47:04
when you're in a health crisis.
47:07
I felt like there was a
47:09
missing person on the health care
47:11
team, so... The job of a
47:13
life care specialist, number one, is
47:15
to educate you on the pain
47:17
medication that you've been prescribed. Then
47:20
we provide non-narcotic pain management techniques,
47:22
things to distract your brain, so
47:24
all of our life care specialists
47:26
are certified also in techniques to
47:28
deal with the mental side of
47:31
the patient when you're in the
47:33
hospital. If you're in the hospital,
47:35
you probably have anxiety, stress, depression,
47:37
and PTSD. Sometimes they need somebody
47:39
to validate their pain, to validate
47:42
their frustrations. Why did this happen
47:44
to me? Why am I here?
47:46
And they don't have that listening
47:48
ear. And then follow up once
47:50
you leave the hospital. Are you
47:53
off your paid medicine? How to
47:55
probably dispose of your opioid. And
47:57
we found that patients, 70% of
47:59
patients didn't even know they were
48:01
taking an opioid. The gentleman said,
48:04
oh my God, I did not
48:06
know. I was taking an opioid
48:08
and my wife is in recovery.
48:10
So I'm so glad you told
48:12
me. So we were able to
48:14
provide a lockbox so he could
48:17
lock up his medicine. You know,
48:19
those are a lot of little
48:21
stories like that. At first, Cammy
48:23
was very strategic. where she placed
48:25
life care specialists, but now she's
48:28
hoping to expand. We started in
48:30
orthopedic trauma because that's where young
48:32
people have their first introduction to
48:34
opioids typically. It's a football injury,
48:36
a car accident, and gymnastics injury,
48:39
whatever the case may be, they
48:41
go home with a big bottle
48:43
of opioids, and that's where the
48:45
problem starts. So we started in
48:47
orthopedic trauma, but we've expanded into
48:50
multiple departments, and now at the
48:52
rural hospital, we're really... were on
48:54
the floor across the board. If
48:56
Christopher would have had a life
48:58
care specialist, if I would have
49:01
had somebody telling me about the
49:03
dangers of the medication he was
49:05
going home with, he would be
49:07
here today. And so I really
49:09
feel like we're saving lives one
49:12
patient at a time and it's
49:14
definitely a preventative role that needs
49:16
to be in every hospital across
49:18
the country. That
49:23
was Cammy Wolf Rice. She is
49:25
founder of the CWC Alliance, the
49:27
Christopher Wolf Crusade. She's also the
49:29
author of The Flight, My Opioid
49:32
Journey. Many thanks to her. And
49:34
of course, Dr. Amy Baxter. She
49:36
is a pain specialist physician and
49:38
also the founder of Paincare Labs.
49:41
You can see her full talk
49:43
at ted.com. Before we go... We
49:45
wanted to give you a quick
49:47
update on Catnod, the equestrian whose
49:50
horse fell on her, and who
49:52
was trying to live with her
49:54
chronic pain drug-free. Cat went through
49:56
a period of complete despair. But
49:58
she read a lot of self-help.
50:01
And finally I just decided that
50:03
it was enough, that I had
50:05
enough of the petty party, and
50:07
that I was going to fight
50:10
for my life, because that is
50:12
at that point what I was
50:14
fighting for. And I decided to
50:16
challenge myself to move and get
50:19
out and just... five minutes a
50:21
day of moving my body and
50:23
those five minutes were tortured. They
50:25
were not easier fun. The five-minute
50:28
walk felt like it took an
50:30
hour and a half every single
50:32
time. But then slowly that five
50:34
minutes became a little easier and
50:37
a little longer and the thing
50:39
that I was torturing myself to
50:41
do every day became the thing
50:43
that was actually getting me out
50:46
of bed every day. How are
50:48
you today? Are you living with
50:50
chronic pain? Yes, and I will
50:52
live in chronic pain very likely
50:54
forever, and that's okay. I have
50:57
a way better mental control over
50:59
my pain. And although, yes, I
51:01
still am like a five or
51:03
six out of ten, almost every
51:06
single day, it's more like background
51:08
noise now, when it's so constant,
51:10
you kind of learn to tune
51:12
it out and you learn to
51:15
focus on the good things in
51:17
your life. You learn to focus
51:19
on... other things that are stimulating.
51:21
Because when all you have in
51:24
your life is pain, that's really
51:26
dark. But if you can bring
51:28
other things into your life that
51:30
bring you joy, bring you happiness,
51:33
keep you moving, keeping you working,
51:35
distracted, it does make it easier
51:37
to kind of let that pain
51:39
level fall into the background. I
51:42
know it's there, but it's something
51:44
I have a way better mental
51:46
control over now. Pain is very
51:48
complex, especially the chronic pain. because
51:51
there is a brain aspect to
51:53
it because your brain is so
51:55
used to being in pain and
51:57
there is the physical aspect of
51:59
it, because obviously most of the
52:02
time it stems from some sort
52:04
of injury or something happening, nerve
52:06
pain, like all of these things.
52:08
And so you kind of have
52:11
to break it apart and treat
52:13
all of the pieces instead of
52:15
just treating one as a whole
52:17
and break that cycle. So for
52:20
me, I found the chronic pain
52:22
clinic and I did what they
52:24
call an ablation, so they cauterized
52:26
a bunch of nerves in my,
52:29
from basically my neck to my
52:31
tailbone. very unpleasant experience, but it
52:33
did help break a little bit
52:35
of the cycle. I was in
52:38
pain-wise because the nerves couldn't communicate
52:40
to my brain the same, and
52:42
that really helped as a reset,
52:44
and then I used that time
52:47
to really strengthen and train my
52:49
body around the injuries to have
52:51
better support, and then I do
52:53
also, I've seen natural pests, and
52:55
lots of people like that to
52:58
help find some natural supplements to
53:00
help with inflammation and pain as
53:02
well that aren't opioids. It's a
53:04
full-time job. Oh, it's a commitment
53:07
for sure, but you know what,
53:09
when your choice is, do I
53:11
commit to not being here anymore,
53:13
or do I commit to finding
53:16
a way through this, and coming
53:18
out the other side stronger, more
53:20
knowledgeable, and to be honest, I
53:22
think healthier right now than I
53:25
was before my injury, I'm going
53:27
to choose that route all day
53:29
long. Are you still involved with
53:31
horses? Yes, actually, so... I am
53:34
training and back to competing and
53:36
have really high hopes for where
53:38
that journey could take us and
53:40
whether that means all the way
53:43
to the Olympics. That's definitely a
53:45
goal. Wow. Does hurt to ride.
53:47
But do I notice it when
53:49
I'm riding? No. Riding is the
53:52
thing that is my therapy and
53:54
a little extra physical pain that
53:56
I can work through from a
53:58
stable and healthy mental place is
54:00
definitely worth it for me. That's
54:03
cat nod. Her book is called
54:05
The Other Side, and you can
54:07
see her TED Talk at ted.com.
54:09
Many many thanks to all the
54:12
people we had on this show
54:14
about pain. relief. This episode was
54:16
produced by Rachel Faulkner-White, Matthew Cloutier,
54:18
Fiona Gyrin, and Chloe Weiner. It
54:21
was edited by Sana's Meshkinpore, and
54:23
me. Our production staff at NPR
54:25
also includes James Delahousi, Katie Montelion,
54:27
Harsha Nahada, and Arin Naguchi is
54:30
our executive producer. Our audio engineers
54:32
were co-Takasougii Chernovan, and Robert Rodriguez.
54:34
Our theme music was written by
54:36
Romtine Arablui. Our partners at TED
54:39
are Chris Anderson, Helen Walters, Alejandro,
54:41
and Daniela Balareso. I'm Manushe Zamorote,
54:43
and you've been listening to the
54:45
TED Radio Hour from NPR. This
54:48
message comes from NPR sponsor Informatica.
54:50
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54:52
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54:54
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54:56
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54:59
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55:01
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55:03
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55:05
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