Estrogen and Progesterone Explained | The ATP Project 494

Estrogen and Progesterone Explained | The ATP Project 494

Released Tuesday, 15th April 2025
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Estrogen and Progesterone Explained | The ATP Project 494

Estrogen and Progesterone Explained | The ATP Project 494

Estrogen and Progesterone Explained | The ATP Project 494

Estrogen and Progesterone Explained | The ATP Project 494

Tuesday, 15th April 2025
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0:03

Steve? Yes. Guess what we're

0:06

talking about today? What? Block

0:08

your ears. Why? All things,

0:10

sex hormones. Oh, testosterone? But

0:12

specifically, unfortunately not today, progesterone and

0:15

estrogen. So we're good, the bad,

0:17

the ugly men as well. We're

0:19

going to be talking about an

0:21

estrogen, progesterone for men. Men? Yep.

0:23

why we need the men as

0:25

well. Wow. What can go wrong

0:27

and what to do when things

0:29

do go wrong? So it's a

0:31

really cool one and probably more

0:34

for the ladies, but the men

0:36

can still listen. Listen up

0:38

men. Yeah, okay, let's get into

0:40

it. Hey guys, welcome to the

0:42

ATP project. You're with your

0:44

host Steve and Nick. Hey Steve.

0:47

Hey, hey Nick, how are you? I'm good, how

0:49

are you? Good, how are you? Good, how

0:51

are you? Good, how are you. So I

0:53

was just talking about Easter and progesterone, but

0:56

I think there's still a lot of confusion

0:58

about that amongst women out there, and particularly

1:00

cycles and things, and when things go a

1:02

little bit wrong, how it can be simple

1:04

imbalances, and so some women still maybe aren't

1:06

fully aware of that sort of thing. So

1:08

we're going to talk a little bit about

1:11

what they do, what happens when they go

1:13

wrong, or they go out of balance, and

1:15

how we can fix it. And you know what I'm

1:17

going to talk about? Yeah, you know, because you

1:19

can't go a whole podcast with that. I

1:21

can't, I can't, look, seriously, this is

1:23

the scary thing that a lot of

1:26

men don't understand is that we need

1:28

pedestrian and we need estrogen. Otherwise, you

1:30

won't be able to reproduce, you won't

1:32

be able to have sex, you need

1:34

it for your erections, Nick. Yeah. You know, like,

1:36

specifically. But you know, there's a

1:38

huge role for me. Now obviously

1:40

this is female focus, because estrogen pedestrian

1:43

pedestrian is the bread and butter of

1:45

women. But men too, and you know,

1:47

we've we've coordinated this, so is it

1:50

we cover both sexes, but it's predominantly

1:52

women-based. So, so, so with, with estrogen

1:55

progesterone, I mean, it's a really tricky

1:57

one because there's, there's three types of

1:59

estrogen. E, two, E, three.

2:01

E, two is the most potent.

2:03

That's estrodite. That's made from testosterone,

2:06

which is made from ultimately cholesterol

2:08

from D, E, E, A, and

2:10

pregnancy alone, all this sort of

2:12

stuff. So, and pedestrian, you know,

2:14

is made from cholesterol as well,

2:16

which again puts the fairy tale

2:19

of cholesterol being a bad thing, you

2:21

know, down at cholesterol. Yeah, cholesterol.

2:23

Well, that's a whole nother thing,

2:25

which we've done many, many, many

2:27

times, but that's a big one

2:29

that I see with women who

2:31

are very underweight and are very

2:34

low fat diets. Believe it or

2:36

not, still see that happening. And

2:38

they have very low cholesterol levels

2:40

and they have hormone imbalances or

2:42

they have very low sex hormone

2:44

levels. And, you know, because they

2:46

don't have enough cholesterol to make hormones.

2:49

production. Absolutely. Well let's

2:51

have a quick one. What what does

2:53

let's start with with estrogen? What does

2:55

the estrogen do in the body? The

2:58

three estrogens and you want to tell

3:00

us a bit about that just basically

3:02

in women? Yep. So there's as you

3:04

said three estrogens. E1 E2 E3 E2

3:07

is the primary one for cycling women.

3:09

Yep. E2 is the primary one for

3:11

cycling women. E-strone. Yeah, E-strain.

3:13

Okay, good. Okay, good. See,

3:15

so and they're synthesized from

3:17

anter's diet or testosterone via

3:20

aromatase. Yep. So keep that in mind

3:22

because for men that that is a

3:24

factor. Yeah, we're going to talk about

3:26

aromatase a bit. We want that for

3:28

women. We don't want that so much

3:30

for men. No. So mainly produced in

3:32

the ovaries, we do have a little

3:34

bit in our fat cells more the

3:37

E-the E-3 and that becomes when we're...

3:39

I mean, a puzzle, that becomes more

3:41

of an issue. Okay, so estrogen basically

3:43

is for growth. So it helps with,

3:45

you know, proliferation of things. So your

3:48

lining of your uterus around your cycle

3:50

and breast growth and all of that

3:52

sort of thing. And that's why women

3:54

have more body fat around the hips,

3:56

button thighs is estrogen driven. So it's

3:59

kind of a growth. type of hormone.

4:01

Wow and in men of course

4:03

it's it has a plays a

4:05

role. It's very much in reproduction.

4:07

The role of estrogen in reproduction

4:09

is there three things and I've

4:11

got a graph here but I

4:13

can't show it because it's got

4:15

a picture of a naughty part

4:18

of a boy. So I'm not

4:20

even going to say Nick that

4:22

because you wouldn't know any about

4:24

that. It's involved in getting an

4:26

erection. and it's also involved in

4:28

sperm production. And that's estrogen. I didn't

4:30

say testosterone there. I said estrogen. So

4:32

very interesting, because we've got it, because

4:35

for hormones, the work you need a

4:37

receptor. And then the receptor grabs the

4:39

hormone and says, what do you want

4:41

me to do? Ah, it's estrogen. I

4:43

want to increase my libido, or whatever

4:45

the case may be. So very, very

4:47

important for men and erections. Now. You don't

4:49

want to go, oh, if it's good

4:51

for corrections, I'm going to smother myself

4:53

in estuisle, and because it'll do the

4:56

opposite effect. It will, yes. It's dose

4:58

dependent. It is, yeah. So very, very

5:00

good estuagen, but. It's a really, really

5:02

important hormone for all sorts of things.

5:04

In women, of course, and you've got

5:07

a great diagram here about how increases

5:09

serotonin in the brain, which is good

5:11

for lots of things. Yeah, definitely. So

5:13

helps with serotonin. I mean, it does,

5:15

and that's the thing with estrogen, progesterone,

5:18

just think, well, it's just for periods.

5:20

Yeah. It does a lot more than

5:22

that. So obviously, estrogen definitely has an

5:24

impact on our bone health, on our

5:26

mental house for our brain, the brain,

5:29

skin health, skin health, skin health, skin

5:31

health, transmitters or that sort of thing,

5:33

gut health as well. So it goes

5:35

well beyond just for cycles and reproduction.

5:38

So it's super important and that's why

5:40

women in menopause have so many problems

5:42

because they lose all these other, it's

5:44

not just them, and menopause isn't just

5:46

about the lack of hormones, it's not

5:49

just a hormone deficiency, it becomes so

5:51

much more and that's because estrogen did

5:53

so much more in the body than

5:55

just sex hormone, you know, reproduction

5:57

and all of that sort of things.

6:00

So there's not many diseases that women

6:02

get more than men. Women live longer

6:04

about four years. They get less cancers

6:06

and always other goodies, less heart disease,

6:08

but they get more Alzheimer's. And one

6:11

of the problems is that is post-menopausal,

6:13

estrogen increases brain-derived neurotraffic factor, which is

6:15

a brain chemical helps keeps your brain

6:17

healthy. And when you go through menopause

6:20

and estrogen levels drop, the rates of

6:22

Alzheimer's and women increase dramatically. Very scary.

6:24

And cardiovascular conditions as well. Yes. Cardiovascular

6:26

issues. So men catch up to men

6:28

when they hit menopause and beyond with

6:31

cardiovascular risk and that... it's men more

6:33

so than women and then when women

6:35

when women hit menopause it evens out

6:37

and that's because they lose that estrogen

6:40

which is protective, cardio protective. So it

6:42

has a lot of really important functions

6:44

in the body outside of just for

6:46

reproduction. And I mean men, if we

6:48

get too much estrogen, which we're very

6:51

heavily prone to if we become obese,

6:53

most men are, I'm 56 and most

6:55

men my age are overweight or obese.

6:57

Yeah. And too many fat cells make

7:00

too much estrogen. And so we tend

7:02

to get all sorts of prostatic problems.

7:04

We get depression, we get impotent with

7:06

too much estrogen, we get... Manboos, gonocomastia,

7:08

and we get all sorts of other

7:11

political depression and cancers. It's very, it's

7:13

tricky because men typically have too much

7:15

esterone, esterogen and not enough testosterone because

7:17

aromatase, that aromatase, that lovely chemical enzyme

7:19

that turns testosterone into esterdyle. Yeah, and

7:22

yeah, as you said, fat cells would

7:24

do that high stress, insulin resistance, alcohol,

7:26

they are all increased rom. Too much.

7:28

Yeah. Yeah. Yeah. I hadn't heard that

7:31

until you said that a few podcasts.

7:33

I thought it was a famous saying.

7:35

Never heard of it. No, never heard

7:37

of it. But it's true. But that's

7:39

that's because of that, that alcohol increases

7:42

aromatose activity. So, and too much. Prolectin

7:44

from the beer. Yeah, Prolectin is another

7:46

one. I've seen Prolectin in men as

7:48

well. So, but anyway, this is an

7:51

about. Real bad for what I mean.

7:53

Yeah, it's not about Prolectin, but Prolectin's

7:55

another podcast on its own, I think.

7:57

Yeah. It's a nasty one. All right,

7:59

so do you want to talk more

8:02

about issues? You wanted to give people

8:04

an overview of progesterin. Yeah. So, so,

8:06

progesterinsterin helps us with ovulation. Yes. So

8:08

that's the ability to release an egg

8:11

for fertilization to fall pregnant. So, but

8:13

it also helps with a nervous system

8:15

function. So it helps with gabber production

8:17

in the brain, which helps with calming.

8:19

Yes. You know, sleep quality and all

8:22

of that sort of thing. And it

8:24

is needed to balance progesterone because of,

8:26

sorry, estrogen. If estrogen was, you know,

8:28

wildly unopposed, that's when we have things

8:31

like cancers and all of that sort

8:33

of thing happening. So we need that

8:35

progesterone to actually balance the levels out

8:37

and keep everything under control, keep the,

8:39

you know, the urine lining from over-proliferating

8:42

and all of that sort of thing.

8:44

So that's really important. Also important for

8:46

immune function. as well. So it has

8:48

again a lot of really important functions

8:51

outside of just fertility and ovulation. It's

8:53

absolutely remarkable. Now in men, pedestrian plays

8:55

a role in all, I've got a

8:57

big table here, it's unbelievable. So in

8:59

the genomic, it actually helps with Spermatogenesis,

9:02

the immune system, respiratory system, helps with

9:04

the prostate and helps keep your weight

9:06

gain under control and it helps. prevent

9:08

brain cancers, believe it or not. And

9:11

any other actions, it increases sperm production,

9:13

increases testosterone synthesis and the light excels.

9:15

Everyone goes, oh, oh, what more testosterone?

9:17

Well, you need progesterone to make your

9:19

testosterone. That's right. Amazing. That's right. Amazing.

9:22

That's right. Also, there's an increase in

9:24

progesterone receptors concentrations in the prostateate. So

9:26

the prostate rate plays a role in

9:28

the prostateate. Helps with the kidneys, helps

9:31

with your central nervous system as well.

9:33

And if you inject a man with

9:35

progesterone, it sedates them. Yes. Yeah. So

9:37

it helps you sleep. Yeah. So I

9:39

mean, that's just, I should actually read

9:42

the reference for those people. I love

9:44

the title of this one, progesterone to

9:46

forgotten hormone in men. Oh, I love

9:48

it. In the aging mom. I'm not

9:51

joking, that's the name of the title.

9:53

and paper so there you go. Isn't

9:55

that interesting? Well it's interesting when you're

9:57

getting sex women tested in males. If

9:59

they go to a doctor you have

10:02

to fight to get estrogen and progesterone.

10:04

I send clients off to the doctor,

10:06

male clients and they get testosterone no

10:08

problem. Yeah. Whereas women, it's harder to

10:11

get testosterone. It's even actually hard to

10:13

get estrogen progesterone now, believe it or

10:15

not, women, but particularly men, the doctors

10:17

won't do estrogen or progesterone. And that

10:19

can be a really important factor when

10:22

you're looking at drivers of some of

10:24

the symptoms of, you know, low mood

10:26

and weight gain and all of that

10:28

sort of thing. So, so really interesting

10:31

that, yeah, doctors are not very open

10:33

to testing these hormones in men. or

10:35

women? Well, I know the answer to

10:37

this. What is it? It's about the

10:39

same, right? It is about the same.

10:42

Yeah, yeah. So postmenopauselly, I mean, we

10:44

did a menopause podcast, we should do

10:46

another one because, yeah, going to more,

10:48

it's very interesting. But postmenopausely, men and

10:51

women have a very similar sex or

10:53

men profile. Yeah, very scary. So what

10:55

problems are that cause? Oh well, go

10:57

back and listen to the the menopause

10:59

podcast, all sorts of problems, all sorts

11:02

of problems. So yeah, and as I

11:04

said, it's it's not just an each

11:06

sex hormone deficiency in in menopause. It's

11:08

what comes with that. Yes. So if

11:11

you treat the underlying things, you can

11:13

balance things out even. We don't without

11:15

having to add in hormones. But but

11:17

yeah, so issue is really important in

11:19

men as well. So So I guess

11:22

we could look at some of the

11:24

signs and symptoms of dysregulated sex hormones.

11:26

Sure. Women's aspect and... Yeah, I've got

11:28

a... beautiful chart here but you go

11:31

here what are some of the signs

11:33

of symptoms what do we look out

11:35

for if we start for estrogen yes

11:37

so if we if someone has maybe

11:39

elevated estrogen then they could have heavy

11:42

bleeding yes you know PMS yeah they

11:44

could have lots of swelling so tissue

11:46

swelling so fluid retention around the waist

11:48

around the hands the feet ankles that

11:51

type of thing mood disturbances fatigue There's

11:53

a lot of, there's a lot of

11:55

symptoms. So that's when it's elevated. Yeah.

11:57

And then when it's low, if it's,

11:59

if it comes quite low, you can

12:02

have hot flushes, you can have night

12:04

sweats, insomnia, joint pain, skin issues, low

12:06

sex drive, mood imbalances, all the things

12:08

that you would have, you can have

12:11

postmenopause, sometimes, I will say sometimes, because

12:13

I've talked about this many times on

12:15

the podcast when I used to compete

12:17

and I had very low sex on

12:19

sex on sex women levels because I

12:22

was very, I didn't have any of

12:24

these sort of symptoms. I didn't have

12:26

the hot flashes, night sweats, insomnia. I

12:28

had none of that. So it depends.

12:31

Yeah, depends on what's going on. But

12:33

that can be a lot of the

12:35

symptoms, cardiovascular issues, obviously bone mineral density

12:37

issues as well, if you have longer

12:39

term lower estrogen when you're still in

12:42

the cycling age. It's incredible. Yeah, so

12:44

I've got scary chart here. Do you

12:46

want me to read my chart out?

12:48

Again, I'll read from the paper, it's

12:51

published in, and this is a funny

12:53

title of this one too, I like

12:55

the title today, estrogen, the necessary evil

12:57

for human health and ways to tame

12:59

it, not making that up. That is

13:02

the title. Okay, so firstly it's got,

13:04

it lists here some of the causes

13:06

of high estrogen, and this is mainly

13:08

women of course, enhances inflammation, inflammation, yeah,

13:11

I did the big one. BPA, bifinyla,

13:13

which is a plastic thing. Also. Alcohol,

13:15

marijuana, heroin cannabis, methadone, amphetamines, but even

13:17

cosmetic progress like fragrance compounds. Any beauty

13:19

products, so anything with those those hormone

13:22

disrupting chemicals, horrendous. And it will say

13:24

for men, marijuana, because I used to

13:26

know a few people that have heavy

13:28

marijuana users, they don't realize it's estrogenic.

13:31

So anyone who's a heavy marijuana user,

13:33

that's something to keep in mind. People

13:35

going to say, oh, well, there's to

13:37

be, you know, cannabis is a great

13:39

treatment, marijuana is great treatment for menopores,

13:42

but people, but people, yeah. is astrogenic.

13:44

Now, diazepam is valium, is a drug,

13:46

it's a benzodazepine, it's a pretty common

13:48

one. And the diseases associated with it

13:51

are the who's who of cancers, all

13:53

the bloody cancers. Even what I found

13:55

interesting, high estrogen can lead to picos,

13:57

policies to govern. I didn't know that

13:59

until I got the paper. But you're

14:02

cancer, gastric cancer, breast prostate cancer, schizophrenia,

14:04

S-L-E, so lupus, MS, multiple sclerosis, male

14:06

gynecomastia, male hypogonadism and obesity it leads

14:08

to. And I've got a list of

14:11

the low estuions. This is for men

14:13

and women as well. Okay, the inhibitors

14:15

of things like antidepressants, like antidepressants, opioids,

14:17

so painkillers. Even estrogens can cause low

14:19

estrogen because it suppresses your natural production

14:22

of it. Yeah, antiandrogens like the pill,

14:24

anti-hypertensive drugs, so blood pressure things, anti-convulsants

14:26

and immunospressive drugs and herbicides, and it

14:28

could lead to osteoporosis, joint pain, Alzheimer's

14:31

disease, Parkinson's, diabetes, and preoclampsia. It's a

14:33

lot, wow. Yeah, and underweight is a

14:35

big one. Yeah, low body weight is

14:37

a big one. And that's, that's why

14:39

women, and it's not specifically menopause podcast,

14:42

but it's a part, a part of

14:44

this, the whole life cycle of female

14:46

humans. Women who are much lighter, like

14:48

very small, women that go through menopause

14:51

a lot of times can have more

14:53

problems because they generally don't have as

14:55

much estrogen. So, or very, very, very.

14:57

you know, very slim women. So one

14:59

of the probably the biggest reasons, because

15:02

I used to see a lot of

15:04

athletes and things, was a menarina, which

15:06

is lack of a period due to

15:08

low issue because they were very thin.

15:11

So high stress also, we'll shut down

15:13

your production as well. So that's another.

15:15

And it screws with the progesterone as

15:17

well, stress, because quartersole is made from

15:19

progesterone. That's right. So it's like if

15:22

you're stressed and you're pumping out loads

15:24

of cortisol your pedestrian by nature is

15:26

low 100% It's just a pleading it.

15:28

Yeah, and again it's it's it's it

15:31

makes sense from a and I'm gonna

15:33

say that's a good thing It doesn't

15:35

sound like good thing. But if you're

15:37

stressed like you know You've got loads

15:39

of pedestrian right now. Let's say and

15:42

you're running away from a tiger. You

15:44

didn't give a shit about pedestrian levels.

15:46

What if your animal is your mortgage

15:48

That's right. You've got 30 years of

15:51

an animal chasing you. Yeah, or your

15:53

work that you go to every day.

15:55

Or you've got kids. Imagine how stressful.

15:57

Here we go. Or he's surrounded by

15:59

toxins or you have infections which can

16:02

create high cortisol as well. Yeah, inflammation.

16:04

Yeah. I mean, and you know, even

16:06

the plastics and the endocrine disrupting chemicals,

16:08

which are everywhere, and people go poohoo

16:11

them a little bit, but you've got

16:13

to remember, they're absolutely everywhere. 40 years

16:15

ago when I was growing up when

16:17

I was done. 40 years ago when

16:19

you were growing up. I was 10

16:22

or 11. So let's say 35 years

16:24

ago when I was a teenager. Oh

16:26

yeah, 30 years, 30 plus years ago.

16:28

I was a teenager 40 years ago,

16:31

easily, very very comfortably. Middle teens at

16:33

that age, 16, I remember, that's 40

16:35

years ago. I know, it's so scary,

16:37

isn't it? I remember listening to Van

16:39

Halen and jump came out this time.

16:42

I was saying that to my partner

16:44

the other day, because he never listened

16:46

to any like Bon Jovi, poison, white

16:48

snake, Iceland, all of these. is like

16:51

power bands with the hair, like cheesy

16:53

as hell. But my partner's like, no,

16:55

I never listen to it neither. And

16:57

I'm like, he's my age. I'm like,

16:59

what's wrong with you? What's wrong with

17:02

him? He's a lot of that stuff.

17:04

He's crank it up in my car

17:06

with my pea plate sign and my

17:08

Mazda 121. Cupay with the sunro. It's

17:11

very cool. I had a Ford laser

17:13

back then. I had a very cool

17:15

car. My point being. 30 years ago,

17:17

we did have some of the chemicals

17:19

around, but nothing like there is now.

17:22

Like if they're everywhere, they're in all

17:24

our beauty products, all our cleaning products,

17:26

our kitchen, you know, plastics and pots

17:28

and pans and... you know, cleaners and

17:31

air fresheners and bin liners with the

17:33

smelly stuff and the plugins that you

17:35

plug in, candles, like the lot, they're

17:37

just surrounded by it. So you need

17:39

to speak to Beck because she loves

17:42

all that crap. Oh yeah, anything with

17:44

a scent that's not natural, obviously an

17:46

essential oil sort of scent is a

17:48

chemical, it's terrible. So you know, people

17:51

put those plug-ins or... They spray the

17:53

air freshener and like I said bin

17:55

liners. So in you're touching the bin

17:57

liner when you're putting it in with

17:59

the centered bin liners. Touching the bin

18:02

liner this morning. Receits as well. So

18:04

shop receipts, anyone that gets all those

18:06

shop receipts with the BPA on them?

18:08

Beck does a lot of shopping. So

18:11

we're surrounded. So they're very significant. So

18:13

when you say to a woman that

18:15

has maybe hydrogen dominance, you need to

18:17

remove the chemicals from your life. Like

18:19

the list can be this long. It's

18:22

really difficult. So you kind of do

18:24

it kind of do it. very significant

18:26

with the endocrine-disrupting chemicals. It's really scary

18:28

because, you know, let's take the woman

18:31

who's, you know, I ran with everybody

18:33

who was good, but that people, women

18:35

like good smelling stuff, and she's very

18:37

sensitive, you know, women are very sensitive

18:39

to smells, and it's like, I'm not,

18:42

I broke my nose when I was

18:44

14, trampoline, so I don't think it's

18:46

ever really recovered from that. Yeah. I

18:48

don't like the smells, they make me

18:51

sick. So there's the headaches and things

18:53

like that. I don't, I'm just really

18:55

sensitive to them. And that can be

18:57

a liver issue as well. So liver

18:59

detoxifications, if some women really struggle with

19:02

sense, like certain smells and things. they

19:04

feel sick headaches that sort of thing

19:06

can be a liver detox factor your

19:08

body can't detoxify the chemical coming in

19:11

and other times it's just I'm just

19:13

hate the smell of it like I

19:15

don't use any of that stuff so

19:17

but um but yeah natural stuff like

19:19

our you know essential oils are great

19:22

that sort of thing oh we put

19:24

oils on the beer we chew it

19:26

on like lavender oil and stuff because

19:28

I love that stuff it smells great

19:31

it smells great it's funny I was

19:33

going to put it out but I

19:35

thought no. They look at men with

19:37

migraines. Women get more migraines than men,

19:39

right? About three to one ratio. I'll

19:42

tell you why too. Because they have

19:44

to put up with men? That's right,

19:46

no. A lot of it's hormonal driven.

19:48

It is. And they measured the hormone

19:51

levels of men that get migraines and

19:53

they've got much higher, significantly higher estrogen.

19:55

Yeah. Isn't that amazing? And you know

19:57

why they they get them the headachesakeses

19:59

and the migraines is because histamines. histamines.

20:02

So histamines and histogens are into wine.

20:04

Yes they are. So estrogen will drive

20:06

up your histamines and histamine will drive

20:08

up your histogens. So when you have

20:11

someone has say histamine issues and they

20:13

get the headaches and they get the

20:15

pain and they get the mood changes

20:17

and... like you know joint pain and

20:19

all that sort of thing and you

20:22

think about what happens with if you

20:24

have an estrogen dominance or high estrogen

20:26

you get the headaches you get the

20:28

heavy bleeding you get you know the

20:31

swelling and all that sort of thing

20:33

it's the it's the histamines wow because

20:35

they're now using as a preventative sand

20:37

margarine which is an antihistamine for migraines

20:39

yeah makes all sense makes a lot

20:42

of sense does and you know it's

20:44

incredible and estrogen and that is very

20:46

and that is very It's really scary

20:48

shit. It's really scary. It's very interesting.

20:51

So you know, if you're a man

20:53

and getting migraines, you can have this

20:55

stuff tested and it can be modifiable.

20:57

Yes. Oh. Detox and all that. You

20:59

know what? I have to say, I

21:02

don't do a lot of hormone stuff

21:04

because I don't really see that. I

21:06

don't really see a lot. of women

21:08

with hormone, I see, or the other

21:11

weird things. Oh, you see some weird

21:13

stuff. But hormones are probably one of

21:15

the easiest things to correct. Yeah, it

21:17

is. I mean, obviously it's always exceptions

21:19

to the rule, but for the most

21:22

part, although hormones are very complex in

21:24

what they do, to balance them, is

21:26

actually relatively easy, as long as you

21:28

take away, you know, contributing factors and

21:31

drivers. Yeah. So, yeah. So, so... Because

21:33

there's lots of causes of things like

21:35

estrogen dominance. Yeah. You know, you've got

21:37

a great list here about the things

21:39

that drive it up. Yeah, I do.

21:42

If you want to talk about that.

21:44

There it is. I've got so many

21:46

papers on the table. I don't know

21:48

where I'm at. The paper, for those

21:51

who are just listening, it's like, we've

21:53

got, you've got books in front of

21:55

you basically. That's one of the most,

21:57

the largest printouts I think we've done

21:59

for a podcast for a long time.

22:02

Most like a phone book, wasn't like

22:04

a phone book, wasn't a lot like,

22:06

wasn't a lot like, like, like, like

22:08

a phone book, like, like, like a,

22:11

like a, like a, like a phone

22:13

book, like a, like a, like a,

22:15

like a, like a phone book, like

22:17

a, like a, like a, like a,

22:19

like a, like a, like a, a,

22:22

like a phone book, like a, like

22:24

a, like a, like a, like a,

22:26

like a, a What are some of

22:28

the things who cause it? Yeah, so

22:31

eigen dominance can literally just be a

22:33

lack of progesterone. It can be something.

22:35

So when we're talking about eigen and

22:37

progesterone, it has to be about ratios.

22:39

It's not about the eigen has to

22:42

be this number and the progesterone has

22:44

to be this number. I mean, yes,

22:46

there are optimal ranges, but you could

22:48

have low eigen and still have eigen

22:51

dominance. Yeah. Because you may have... even

22:53

lower pogesterone, right? So the imbalance is

22:55

still there. So it's all about the

22:57

ratios, as I said at the beginning.

22:59

You need pogesterone to balance out estrogen,

23:02

otherwise you're going to have issues. It

23:04

regulates aromatase, so they certainly regulate each

23:06

other, absolutely. So, estrogen dominance could purely

23:08

be a lack of pogesterone. Okay. That

23:11

could be it. You could have... perfectly

23:13

normal levels of estrogen and very low

23:15

progesterone. It's just not ovulated for some

23:17

reason that could be because progesterone spikes

23:19

after day 14 dramatically. That's right. So

23:22

yeah so it could be lack of

23:24

progesterone. It could be inflammation as we

23:26

said that's a really big driver. It

23:28

can be chemical chemical issues as we

23:31

said chemical you know exposure, infections. molds

23:33

and things would then disrupt the microbiome

23:35

which would disrupt our hormonal production. Any

23:37

liver, liver detoxification issues, so inability to,

23:39

that phase two detox and therefore you

23:42

can circulate, recirculate estrogen, constipation is not

23:44

the one, guts. imbalances. So gut dysbiosis,

23:46

because we have, well there's two things

23:48

going on in the gut, we have

23:51

the Easter Bolom and we have, we

23:53

also have bacteria that produce beta-glucuronidase. Yes.

23:55

And so they can both impact our

23:57

hormone, our estrogen levels as well. Stress,

23:59

as we said, is another one that

24:02

can drive it up as well. So

24:04

yeah, there's this myriad of myriad of

24:06

things. And what about being overweight as

24:08

a woman? they are overweight because they've

24:11

got high estrogen or estrogen dominance because

24:13

they're overweight, but it can be they

24:15

overweight because they've got estrogen dominance. Correct.

24:17

And they start putting on fat in

24:19

areas that are feminizing, but not ideal.

24:22

Yeah, that's right. And then the problem

24:24

is the more fat cells, the more

24:26

fat you have, the more estrogen of

24:28

that E3 you produce as well. So

24:31

a lot of women, again, I'm going

24:33

to say postmenopausal, because they're a good

24:35

example of when you need levels are

24:37

low. put on a lot of weight

24:39

and then you do their hormones and

24:42

they're very high estrogens. Yeah, but they're

24:44

the E3 and it's coming from the

24:46

fat cells. Yeah, so the more fat

24:48

you have the more estuogen you'll produce

24:51

fat cells. And I guess it's fair

24:53

to say that as a woman ages

24:55

they do less activity, exercise like strenuous

24:57

exercise. Yeah. I mean that's not necessarily

24:59

the case, but at the gym I'm

25:02

one of the oldest, I'm one of

25:04

the oldest there. And this one of

25:06

the oldest, I'm one of the oldest

25:08

if not... you know, the oldest. Because

25:11

there's a lot of young people to

25:13

go into the gym doing exercise. Not

25:15

many old farts like me there. And

25:17

it's the old farts like me that

25:19

need to go to the gym. Yeah.

25:22

You know, when they're 20, they're already

25:24

musilly and everything. And that's the thing

25:26

that makes me laugh is people get

25:28

older. They're not everyone, probably not ours.

25:31

so much but a lot of people

25:33

train less and so that's when you

25:35

actually have to train more yes you

25:37

have to be there should the gym

25:39

should be full of old people because

25:42

that's really important to maintain you know

25:44

muscle mass and physical yeah because young

25:46

men have and women they've got muscle

25:48

to but they've got help yeah I

25:51

mean that's why I probably wish I've

25:53

probably got upset people it's on here

25:55

but you have the young you know

25:57

influences young female influence fitness influence on

25:59

Instagram and they're saying here whether I

26:02

eat in a day you know and

26:04

they've got these masses of plates of

26:06

food and through my breakfast lunch and

26:08

dinner and they're they're super fit and

26:11

they're like you know this is what

26:13

I eat in a day and a

26:15

train and it's really easy and it's

26:17

like that best because you're 20 yes

26:19

like you have the hormonal profile to

26:22

help you there you have the resilience

26:24

you have everything else but you have

26:26

the muscle mass so as you you

26:28

you get older and you lose the

26:31

estrogen you lose that that that resilience

26:33

that resilience and you have more you

26:35

have more you know you know adrenal

26:37

issues and you know adrenal issues and

26:39

you know adrenal issues It's a lot

26:42

harder. So everything's easier when you're younger.

26:44

People may disagree, but believe me, it's

26:46

only the young people that don't disagree.

26:48

Because when you get older, you realize.

26:51

Life's on easy mode when you're young.

26:53

And I know you're right, I'm going

26:55

to fence, I'm going to fence, I'm

26:57

saying, someone's saying that, but it is,

26:59

they have health, they have health, they

27:02

have all these sorts of things going

27:04

for them, and it's really. I just

27:06

had to go. Yeah. Because you have

27:08

to go. You have to go. You

27:11

definitely have to go. So yeah, you

27:13

definitely is a lot harder. I skated

27:15

through to be honest my training when

27:17

I was younger. I never dieted really.

27:19

I trained, I didn't have to train

27:22

super hard, maintain muscle mass now. I

27:24

have to really really go hard. Yeah.

27:26

And then you know, then you have

27:28

sort of your... your reproductive years where

27:31

you then have babies and things and

27:33

then you have menopause. So we have

27:35

like major rollercoaster changes whereas men don't

27:37

and the testosterone is fairly standard the

27:39

whole way through obviously less imbalances, so

27:42

weight loss, weight maintaining a healthier weight

27:44

and muscle mass is a lot easier

27:46

for men. So there's that. I mean

27:48

I've got a child. here of what

27:51

happens to progesterone through the month. Look

27:53

at the waivingness of those things. It's

27:55

like a bloody pip, pip, pip, pip,

27:57

pip, pip, yeah. And then it's funny,

27:59

so estrogen sort of goes like this

28:02

in puberty and perimenopause, it's like just

28:04

scribbling library page. And that's why you

28:06

have so many symptoms when you're young

28:08

and you go through puberty and so

28:11

many symptoms in your late perimenepoles and

28:13

moving into menopores because you're... Hormones are

28:15

just wildly like, pedestrian is, pedestrian is

28:17

a bit calmer, but you know, in

28:19

menopause, perimenopause, it's starting to just slow

28:22

the decline, but your issues are going

28:24

like this. All over the place. And

28:26

interestingly, same with puberty, it's really interesting

28:28

because the amount of clients I've seen

28:31

over the years where mothers have bought

28:33

their daughters to see me because they've

28:35

been put on the pill, because they

28:37

are they don't have a period, they

28:39

have, you know. like a testosterone type

28:42

dominance or they're told they have PCOS

28:44

and they put them on the pill

28:46

and the majority of the time it's

28:48

none of that. So women, it can

28:51

take girls, it can take a couple

28:53

of years for a cycle to start

28:55

to regulate. So a girl when she

28:57

goes through puberty may not start to

28:59

have regular cycles for a couple of

29:02

years. She may have a few, they're

29:04

not a few because of this wild

29:06

sort of fluctuations while her body's adjusting

29:08

to the new profile. And so they're

29:11

wrongly diagnosed with PCOS. Every woman has,

29:13

like, sists on her ovaries. Like, they're

29:15

actually follicles, right? Every woman does, and

29:17

at certain times of the month, they

29:19

have more than others. If they don't

29:22

ovulate, they're going to have more. It

29:24

doesn't mean they have PCOS. So there's

29:26

a lot of PCOS. It's been misdiagnosed,

29:28

but for young girls particularly, I see

29:31

it a lot, and they put on

29:33

the pill, and they put on the

29:35

pill at 13, 14, 14, 14, 14,

29:37

14, 15. it just messes them up

29:39

for how long the next however many

29:42

years so they've got them we've got

29:44

to get them off it and so

29:46

that's a really big thing I see

29:48

and it's just the normal you know

29:50

it's like saying to women going through

29:53

perimenopause into menopause well you should should

29:55

be going, cycling, not a problem, bang,

29:57

into menopause and straight, all smooth rides.

29:59

Same thing as with puberty, it's not

30:02

smooth. So any women out there that

30:04

have young girls that are going through

30:06

puberty, you know, going through puberty in

30:08

the early stages and maybe it's a

30:10

bit rocky, don't jump straight on the

30:13

pill because... There's things you can do

30:15

to try and calm things down. How

30:17

many women like, let's take a 20

30:19

year old woman, how many 20 year

30:22

old women on percentages would you guess

30:24

are on the pill? I'm sure we

30:26

could look this. Most of them would

30:28

be a lot. I mean, I guess

30:30

these days it's a bit more people,

30:33

women are all aware, the dangers that

30:35

the pill can have, but look, I

30:37

wouldn't even, there'd be a lot. I

30:39

think they just passed a law week

30:42

and PBS. the third generation pill. Yeah,

30:44

which is like yes and Diane 35

30:46

and the problem that is. And then

30:48

the women are celebrating that. Really? Yeah.

30:50

You know the side effects of those?

30:53

stroke. Yep. And like we were talking

30:55

about whether it's out or not we

30:57

did a methylation podcast. Yeah. Methylation factors

30:59

if you have, you know, the MTRFAR

31:02

snips more can be more predisposed to

31:04

clocks and things. You should not be

31:06

on the pill if you have MTRFIF

31:08

polymorphism. So there's a lot of potential

31:10

issues with that and then a lot

31:13

of women they come off the pill

31:15

and they have you know post pill

31:17

acne and all that sort of thing

31:19

and so then they what they do

31:22

is they they get the bad acne

31:24

so they go I can't come off

31:26

the pill so they get back on

31:28

it again yeah and there's so many

31:30

there's so many factors around the pill

31:33

and obviously you know someone wants to

31:35

do the pill your choice but there's

31:37

a lot of forms of contraception that

31:39

are safer that you can do as

31:42

well so that don't have as big

31:44

an impact and you know when you

31:46

think about their synthetic hormones for one

31:48

they're shutting down your own production obviously

31:50

you know they're creating creating a lot

31:53

of issues with mood imbalances and you

31:55

know histamine issues and remember they're not

31:57

human hormones like they don't give you

31:59

progesterone in a pill they give you

32:02

progesterone levels are flat. Yeah, synthetic form,

32:04

which is terrible. Yeah, there can be

32:06

a lot of really negative impacts. It's

32:08

even in these chartier progesterone levels, you

32:10

can see that on the pill where

32:13

the red one is the progesterone. Yeah.

32:15

And it's just high. Yeah. And it's

32:17

not even a natural hormone. No. No.

32:19

Normal progesterone levels are flat. Yeah. Which

32:22

shouldn't be. You need a big pump

32:24

at the end of your cycle. Yeah,

32:26

we should actually do a podcast, I

32:28

don't know, on coming off the pill,

32:30

because so many women struggle with it,

32:33

some ways to actually get off the

32:35

pill and not have some of these

32:37

issues that come with that. But yeah,

32:39

it's, yeah, if you're on the pill,

32:42

if you're on the pill for anything

32:44

other than contraception. like for hormone and

32:46

imbalances, just sort out the hormone imbalance,

32:48

don't use the pill for that because

32:50

you're not actually fixing the problem, you're

32:53

just masking the problem, and as soon

32:55

as you come off the pill the

32:57

problem is going to come back. So

32:59

yeah, so what was that, istergen? So

33:02

yeah, so what are the consequences of

33:04

having too much aschen as a woman?

33:06

What are the things that can do?

33:08

I mean through some of the more...

33:10

benign or not benign but some of

33:13

the other things you look watch out

33:15

for. So some of the consequences obviously

33:17

heavy bleeding heavy periods and things like

33:19

that very so if you've got very

33:22

sorry TMI whatever but very a big

33:24

clots yeah in the When you're bleeding,

33:26

that can be a sign of high

33:28

estrogens as well because it causes clotting.

33:30

Stickiness of your bloods. Fiberoids, it could

33:33

be for some people. Endometriosis, no, but

33:35

yes in a way because if you

33:37

have endometriosis is more of an autoimmune.

33:39

type picture. It's a very inflammatory driven

33:42

and possibly even infection driven, but that

33:44

can then, you know, if you have

33:46

high estrogen, that's going to make it

33:48

worse. So inimetriosis can be one. Obviously,

33:50

aromatization, if you have a lot of

33:53

estrogen and inflammation, you can aromatize to

33:55

testosterone, which then can become more of

33:57

a testosterone issue. So breast cancers and

33:59

things like that can also be a

34:02

consequence as well in fertility as well

34:04

can be a consequence insulin resistance Metabolic

34:06

issues that sort of thing it's funny

34:08

you said in fertility that that that's

34:10

weird because that would normally be low

34:13

issue but it's again high or low

34:15

yeah high because generally if you've got

34:17

high issues and you've got issues with

34:19

progesterone or you know that some of

34:22

the drivers so inflammation yeah and even

34:24

polymorphism so MTHFR C-O-M-T, they can be

34:26

factors as well. So, M-T-H-F-R, obviously you

34:28

don't detoxify your estrogens very well, so

34:30

therefore you can have a build-up. The

34:33

comp, you know, is involved in that

34:35

as well. So... We did a podcast

34:37

in about a week ago, Nick? We

34:39

did. A week here, right? Yeah. So,

34:42

yeah, so, so there's some of the,

34:44

some of the consequences of high estrogens.

34:46

So, you know, you know, if you

34:48

have... hormonal imbalances, you don't just, and

34:50

a lot of them just suck it

34:53

up. No, a lot of them think

34:55

it's normal. Even, even PMS, women think,

34:57

oh, it's part of it. Yes. It's

34:59

actually not, it's common, but it's not

35:02

normal. You shouldn't have pain and you

35:04

shouldn't have all these issues. It's like

35:06

obesity, it's common, but it's not healthy

35:08

normal. That's right. You should just, if

35:10

you're serious, you just arrive, you just

35:13

arrive, knowing, obviously tracking it, tracking it,

35:15

but you're tracking it, but you shouldn't

35:17

have any symptoms, but you shouldn't have

35:19

any symptoms, but you shouldn't have any

35:22

symptoms, it's not normal to have and

35:24

generally for even something is is benign

35:26

and say PMS is can be related

35:28

to an imbalance. And there's PMDD too

35:30

which is even worse. That's a really

35:33

that's a really severe one. I mean

35:35

I've seen clients that are suicidal. Oh

35:37

really? Yeah really horrendous and we've been

35:39

able to rectify that and they've actually

35:42

got you know got their life back

35:44

because a lot of these women really

35:46

are seriously suicidal. So you know, that's

35:48

a really severe sort of form of

35:50

PMS, but yeah, there's definitely things we

35:53

can do that. It's just a it's

35:55

just a significant imbalance. So do you

35:57

want to move on to progesterone? Yeah,

35:59

progesterone. Yeah. So what are some of

36:02

the consequences of low progester. Oh yeah,

36:04

this is common, low progester. Yeah, or

36:06

high progesterone also is a thing, but

36:08

generally low progestering. So irregular cycles, so

36:10

you can have a shorter cycle, so

36:13

or you can also have, so mid-cycle

36:15

spotting, is generally can for the most

36:17

part be an indication of low progesterone

36:19

because progesterone holds a period in. So

36:22

if your progesterone is very low, you

36:24

can have spot in. So something would

36:26

say I get my period every two

36:28

weeks, well they you're not. You're actually

36:30

probably just got low progesterone and you're

36:33

not holding it in. That's really, so

36:35

that's quite common. Infatility obviously because if

36:37

you have low progesterone you're not going

36:39

to be ovulated and you need to

36:42

ovulate to feel pregnant. Anxiety and insomnia

36:44

because it has that gabenergic calming. And

36:46

that's why again postmenopausal women they can't

36:48

sleep. They have they have anxiety and

36:50

insomnia because they have... They're perpetually stressed

36:53

and they're perpetually stressed. And what I've

36:55

noticed about women that are perpetually stressed

36:57

is they often get a cortisol belt

36:59

around here because they make more pedestrian

37:02

and they therefore make more cortisol from

37:04

it. And as you correctly point out,

37:06

it shunts it down this cortisol pathway.

37:08

They've got fat on their belly, subcutaneous

37:10

fat and it's disturbing when you see

37:13

someone like that. It's highly stressed, they

37:15

can't sleep, they're just stressed and it's

37:17

horrible. It's awful. So thorough dysfunction as

37:19

well. So they're low energy and they're

37:22

depressed as well and they never seem

37:24

to get better. It's not like, like

37:26

people get depressed acutely, but these people

37:28

are chronically depressed. Yeah. They just. Flat

37:30

they've got nothing really flat. Yeah, so

37:33

hard to work hard to do anything

37:35

Yeah, so and then if you have

37:37

high progesterone So generally we see we

37:39

can see high progesterone in PCOS Hmm.

37:42

So a lot of time well generally

37:44

again not always but with PCOS you

37:46

get high luteizing hormone Yeah, and luteizing

37:48

hormone is what drives up progesterone. So

37:50

if you have PCOS and someone says

37:53

oh, you know, you're not cycling a

37:55

regular regular picture piece Take some biotechs,

37:57

which we'll talk about treatments, but take

37:59

some biotechs, or chase trees, it's called

38:02

as it's called, because it helps with

38:04

ovulation, that actually drives up lute-nosing hormone.

38:06

So if you have PCOS, classic PCOS,

38:08

with high lute-nosing hormone, you're going to

38:10

make your symptoms worse. So you have

38:13

a careful with that. But generally, if

38:15

you have hypergester and that's... if you

38:17

have high lute-nosing hormone it can drive

38:19

progesterone up. But otherwise, progesterone, you know,

38:22

it's less likely to be high, it's

38:24

more often low if there's an issue.

38:26

So yeah, that's that. Nice, all right.

38:28

So that's very interesting. So yeah, so

38:30

we usually find in women, usually high

38:33

progesterone, high estrogen low progesterone, and you

38:35

get all sorts of problems with that,

38:37

and it's caused by the gut and

38:39

all sorts of things. Right, so what

38:42

would you, what would you recommend with

38:44

regards to testing for this? Because, yeah,

38:46

okay, let's say I'm a woman, I

38:48

identify as a woman, you know, that

38:50

sort of thing. And I think I've

38:53

got high issues in low pedestrian, low

38:55

pedestrian. Now, given that hormones fluctuate all

38:57

over the place, there's got to be

38:59

days involved when you test for these

39:02

things. Can you go through what you

39:04

test for for hormones? Yeah, so generally,

39:06

depending on the severity, depending on the

39:08

severity. most affordable, easy to do. But

39:10

when you're testing for hormones, you have

39:13

to test at certain times of the

39:15

months to capture whatever hormone you're looking

39:17

at. So a lot of times women

39:19

say, I went to the doctor and

39:22

they had my hormones tested and they

39:24

said everything was fine. Well, what part

39:26

of the months did they test them

39:28

in? Or I don't know, or how

39:30

do you know they're fine then? So

39:33

you have to, so. particularly if we're

39:35

looking at progesterone and that'd be the

39:37

first thing I would look at because

39:39

you can generally tell from a symptom

39:42

picture when someone's telling you the symptoms

39:44

whether it be more estrogen issue or

39:46

low progesterone or that type of thing.

39:48

So I always generally start with progesterone.

39:50

So you really have to test day

39:53

nine, between day 19 to 21 of

39:55

your cycle around about. Spikes. Yes, both

39:57

to spike. Seven to ten days before

39:59

your period is. do. That's when you

40:02

would, you know, sort of be looking

40:04

at it would be higher. So you're

40:06

in the middle of ovulation. But that

40:08

will change to every woman. So if

40:10

you have a 28 day cycle, that's

40:13

around the 19 to 21 day. If

40:15

you have a 32 day cycle, then

40:17

you're looking at sort of 21, 23.

40:19

So you've got to sort of move

40:22

it with whatever cycle length you have.

40:24

Yep. And if you have a very

40:26

sporadic or irregular cycle, it makes a

40:28

lot harder to actually. you sort of

40:30

test around day five ish. Yeah, but

40:33

you can also check estrogen when you're

40:35

looking at pedestrian because if your estrogen

40:37

is very high in during ovulation then

40:39

that's an indication that it is quite

40:42

high throughout the rest of the month.

40:44

So there's sort of what so you

40:46

really want to make sure that you're

40:48

testing the right time of the month.

40:50

to capture these hormones. Testosterone you can

40:53

test any time of the month, it's

40:55

fine. And then you're luteinizing hormone and

40:57

your follicle stimulating hormone will also change

40:59

throughout the month as well. Spights in

41:02

the middle day for them. Yeah, exactly.

41:04

So you want to test at certain

41:06

times the right time of the month.

41:08

So if you're going to the doctor

41:10

from hormone test, don't just go any

41:13

time and then your doctor. So you

41:15

may have estrogen dominance. So they might

41:17

be testing you in that lately to

41:19

your phase where your estrogen. may not

41:22

be where it's supposed to be anyway.

41:24

So they think, no, it's fine. So

41:26

you have to do it at certain

41:28

times. So that's blood testing. And then

41:30

you can go one further and do

41:33

Dutch testing. Dutch, well, so we have

41:35

to go overseas to get a test.

41:37

Dutch testing. Dutch testing. Yeah. And it's.

41:39

the gold standard. It's really good. Yeah,

41:42

really good. It looks at all the

41:44

metabolite. So your E1, E2, E3, and

41:46

then the pathways that they go down.

41:48

So it's really, really cool test. I

41:50

love that test. I've seen it. So

41:53

then you can look at, you know,

41:55

whether you're metabolizing down a healthy pathway.

41:57

So an O2. pathway or more of

41:59

the more of the proliferative pathways which

42:02

are more dangerous. Methilation, the whole thing,

42:04

it's a really great test. So and

42:06

that can give a really good overview

42:08

and you're generally doing four samples throughout

42:10

the day. So you're sort of catching

42:13

all those spikes and things like that.

42:15

Again, it's still only capturing that day.

42:17

Yes. So if you really want a

42:19

really comprehensive hormone profiling, you do a

42:22

28 day. cycle mapping. So you test

42:24

every day and it'll give you a

42:26

whole month of tracking your cycle. That's

42:28

a great test. How much is that?

42:30

It's a bit, yeah. It's a bit,

42:33

yeah. It's a bit worth it. It's

42:35

not, you know, the Dutch test is

42:37

around about, oh God, I haven't done

42:39

a Dutch just a little while because

42:42

there's a big gut testing. It's around

42:44

400-ish. The Dutch, which is affordable. 28

42:46

days cycle mapping, I can't remember to

42:48

be honest, but it's still affordable and

42:50

if someone is having really significant symptoms,

42:53

then it's definitely worth it. The girl

42:55

off mass, she was hanging with the

42:57

PMDD. Definitely something like that, you know,

42:59

and a lot of women, you know,

43:02

can feel great for certain part of

43:04

the month and then feel horrendous. So,

43:06

so the 28 day cycle mapping can

43:08

be great for a lot of women.

43:10

But most times I would go with

43:13

the Dutch first. Yeah, you can get

43:15

a lot of really good information from

43:17

that. So they're kind of the two

43:19

sort of testing strategies that I would

43:22

recommend. I'll give you a hypothetical which

43:24

is common out there. Let's say you've

43:26

got, whichever tests do, you've got higher

43:28

estrogen and lower progesterate, have you got

43:30

any sort of treatments for those common

43:33

sort of, that's a common complaint out

43:35

there. Yeah, that's probably the most common.

43:37

Most common. So the first thing, I

43:39

see you do the blood testing to

43:42

check whether they have high lute nosing

43:44

hormone, that's that type of thing. Vitex

43:46

is probably the first protocol. The reason

43:48

being because it helps to increase that

43:50

it. increases luteizing hormone which then you

43:53

know increases pugesterone. So a lot of

43:55

times as I said it may just

43:57

be that not your pugesterone is high

43:59

but just you have low pugesterone. So

44:02

biotechs can be really good to begin

44:04

with. If you also have high estrogen

44:06

and you have problems with detoxification then

44:08

you're wanting to add in things to

44:10

help with detox so that can be

44:13

something like broccoli sprouts is really good

44:15

for that. We did. We did a

44:17

podcast and my whole podcast on just

44:19

broccoli sprouts. Yeah, and then another of

44:22

the support, obviously, will help with that

44:24

as well. But, you know, that can

44:26

be a really good start, just, you

44:28

know, Vitex and some broccoli sprout just

44:30

to help with, increase your progesterone and

44:33

help to detox your, your estrogen. If

44:35

your estrogen is high, though, you want

44:37

to find out why. So if you

44:39

have gut imbalances, then... you're going to

44:42

need to treat the gut, otherwise you're

44:44

going to still have an issue. As

44:46

I said, it could be a dysbiosis

44:48

and you could be producing a lot

44:50

of beta-glucuronidase, which will actually de-conjugate bound

44:53

estrogen that's ready for diox and re-absorbit.

44:55

And that can be because you're just

44:57

feeding too many of those bugs that

44:59

produce the bitticochoronidase. And then we have

45:02

the istobolo. So it helps to, you

45:04

know, you know, reabsorption of estuption of

45:06

estuagens of estuigens of estuagens, and things

45:08

like, and things like, and things like,

45:10

and things like, and things like, and

45:13

things like, and things like, and things

45:15

like, and things like, Interestingly, postmenopor, so

45:17

you don't, you want to make sure

45:19

your Easter Bolom is balanced. Postmenopause, you

45:22

actually want to have higher levels of

45:24

beta glucor nowadays in your gut. To

45:26

re-absolve the issue? Yeah, of course. So

45:28

when you're, when you're cycling, lower levels,

45:30

when you're not high levels, it'll actually

45:33

help to, you know, keep that Eastergen

45:35

and reabsorbing. Yeah, yeah, it's a really

45:37

good idea. Didn't think of that earlier

45:39

that earlier, but then, right, right, right,

45:42

right, right, right, right, that's good, that's

45:44

good, that's good, that's good, that's good,

45:46

yeah. Yeah. So yeah, so there's some

45:48

of the things you can do and

45:50

obviously it's not it's usually not as

45:53

simple as that because we want to

45:55

look at the reason why The things

45:57

are in balance. So is there an

45:59

inflammatory condition you need to treat? Is

46:02

there a high stress we need to

46:04

treat? Is there? You know High exercise

46:06

loads or someone's exercising over exercising and

46:08

I see this a lot, dietary factors,

46:10

so low-carb will push down your progesterone

46:13

nine times out of ten. So women

46:15

who are low-carb and they go, well...

46:17

What's wrong? I'm not, you know, my

46:19

cycle has changed. Generally, you need the

46:22

carbohydrates for that progesterone production. An insulin

46:24

drives up estrogen because it drives up

46:26

aromatase. That's right. So high carb diets

46:28

on the other hand are a problem

46:30

as well. Yeah. So you need to

46:33

get that balance right. High sugar diets

46:35

and all that's obviously are not good

46:37

either. What about drinking milk for your

46:39

bones? Yeah. You want to avoid cows

46:42

milk. Particularly A1 cows milk is the

46:44

biggest one, but... Milk's in general, it's

46:46

got the IGF one in it, so

46:48

that's a problem. And shall I grow

46:50

a factor one for cancers? Yeah, exactly.

46:53

So yeah, so definitely I would say

46:55

remove dairy, any sort of cycle or

46:57

hormonal problems, just across the board. And

46:59

then work on gut health as well,

47:02

would be a big thing or check

47:04

your gut, so do a gut microbiome,

47:06

test that sort of thing. You know,

47:08

any other conditions, autoimmune conditions, you need

47:10

to find the cause of those, that

47:13

sort of thing. So yeah, all the

47:15

drivers, as I said, high training is

47:17

probably one I see a lot, open

47:19

training, and then low body fat, but

47:22

it doesn't have to always be low

47:24

body fat. So that's a big one

47:26

as well. And the stress, as we

47:28

said, like sleep, you know, all the

47:30

things there. So there are things you

47:33

want to be looking at. Okay. And

47:35

then this is like the gold. like

47:37

the gold standard triple or triple gold.

47:39

Triple gold. We're looking at supplements is

47:42

the magnesium zinc and B6. Oh yes

47:44

for the brain and all that. Yeah,

47:46

that's really good. So all of them

47:48

magnesium really important helps to lower obviously

47:50

inflammation, helps nervous system, helps with progesterone

47:53

receptor sort of activity. The zinc, obviously,

47:55

if there's any testosterone issues or aromatase

47:57

issues, helps to... to sort of counter

47:59

that a little bit. And the B6,

48:02

particularly good for ovulation and that type

48:04

of thing. And also breaking down histamine,

48:06

zip history as well. So paradox of

48:08

five phosphates, our favorite form, is it?

48:10

Yeah, definitely. Yes, P5P. Look for P5B

48:13

definitely. P5P, there you go. Yeah, so

48:15

that, and I think I've been to

48:17

blank here. Amiga three. Amiga three oils.

48:19

Amiga three oils are amazing. I always

48:22

put them in with any, well I

48:24

put them in with a lot of

48:26

things anyway, particularly sort of hormonal things

48:28

because they do help with reducing inflammation.

48:30

They help with the neurotransmitter, they help

48:33

with cardiovascular, they're very good at dampening

48:35

inflammation and kukumen. is another really good

48:37

one as well for inflammation. A lot

48:39

of women that get, you know, period

48:42

of pain, they take the neuroferns, the

48:44

classic, you know, thing, and we try

48:46

to avoid taking neuroferns, it screws your

48:48

kidneys. Definitely, yeah, yeah. So there's things

48:50

if you have, particularly have pain, you

48:53

can do things like. ginger can help

48:55

Boswilia can help cramp bark is another

48:57

really good one by the herb. Yeah.

48:59

It was huge and expensive when I

49:02

was prescribing. Yeah all the herbs are

49:04

like the tinctures and things are very

49:06

expensive now unfortunately. But your cramp bark

49:08

can be quite good as well and

49:10

Boswilia, those types of things can be

49:13

good for the pain inflammation. Oh that

49:15

is a good one. Yeah, yeah so

49:17

they're helpful as well. And then as

49:19

I said you saw for a phone

49:22

from your broccoli sprout. Yeah. Yeah, so

49:24

there's lots of things we can do,

49:26

but again, like everything you want to

49:28

look for the underlying cause, because otherwise

49:30

you're just bandating everything, you can give

49:33

these supplements, but you need to know

49:35

why. These imbalances are happening. So, yeah,

49:37

so there's lots of, lots of things,

49:39

but my first suggestion will be get

49:42

some testing done. Yes. Start off with

49:44

some blood testing or Dutch testing, you

49:46

have to go through a practitioner. Blood

49:48

testing, you can go through your GPs.

49:50

you the full range of hormones to

49:53

get done. And then from there, but

49:55

if you know, if you want to

49:57

start out doing something, I wouldn't suggest

49:59

Vitex without checking whether you have PCOS

50:02

or not, if you have an irregular

50:04

periods. But otherwise, if you don't, you

50:06

can try Vitex, but your magnesium. easy

50:08

to put in, zinc's easy to put

50:10

in, your omega trees are easy to

50:13

put in, and cucuman, and in broccoli

50:15

sprouts. So there are all good things

50:17

you can start with without too many

50:19

problems, but obviously speak to a practitioner,

50:22

speak to a doctor, all the things,

50:24

but if you want somewhere to start,

50:26

look at that, but get some testing

50:28

done and look for underlying causes, insulin

50:30

resistant is another reason for it, it's

50:33

just becoming more and more prevalent as

50:35

well. So yeah. Wow, Nick. It's so

50:37

complex. And you know, I see a

50:39

practitioner, you know, you're in practice, Nicole

50:42

Brown, that tropical, that tropicality, if you

50:44

Google that. And I know you don't

50:46

quote do hormones, but you do hormones.

50:48

But you do hormones. I just for

50:50

some reason don't, I attract more complex.

50:53

All the complex, really weird cases, but

50:55

I do. All the complex, really weird

50:57

cases, but I do. All the complex,

50:59

really weird cases, but I do. I'm

51:02

doing a lot more menopause. So, but

51:04

I do treat women with problems as

51:06

well. I don't do fertility though. I

51:08

will say that because it's as a

51:10

whole emotive area I don't want to

51:13

get into. Yeah, it's scary, but wow,

51:15

this is incredible. It's incredibly toxic. It's

51:17

incredibly toxic, incredibly helpful, depending on the

51:19

hormone you've got in the level. It

51:22

can be your Savior, it could be

51:24

great for men, it's bad for men,

51:26

it's very complex. It's very complex. And

51:28

you need the right. Scary stuff I

51:30

reckon you have too much you don't

51:33

know you've got too much of this

51:35

well you don't and and and if

51:37

you are a female that has cycle

51:39

problems or you know PMS or any

51:42

any sort of issues skin issues or

51:44

acne and things like that It's you

51:46

don't have to put up with it.

51:48

It's not normal. No. It's not it's

51:50

not normal. It's common as not normal.

51:53

So there's always things you can do.

51:55

So you don't, you should not be

51:57

having sort of symptoms and things with

51:59

your cycles. So, or if you don't

52:02

have a cycle at all, then work

52:04

on that as well. Because it's not

52:06

just about, sorry, I'm not just about

52:08

the hormones, it's what the hormones do

52:10

outside of reproduction. So for instance, when

52:13

I didn't have a... period for nine

52:15

years because I was training and I

52:17

was very underway. I don't care because

52:19

it was easy because I didn't have

52:22

to worry about it. But luckily for

52:24

me, I didn't have any bone issues,

52:26

but you have to think about your

52:28

bone health, you have to think about

52:30

cardiovascular health, you have to think about

52:33

cardiovascular health, you have to think about

52:35

cardiovascular health, you have to think about

52:37

your brain health, you have to think

52:39

about cardiovascular levels up for as long

52:41

as you can, even moving into perimenipores

52:44

if you can. you know, as long

52:46

as you can, obviously they're going to

52:48

drop off eventually. But for outside of

52:50

reproduction, there's a lot of health reasons

52:53

we want to have good levels of

52:55

our sex hormone. So you need to

52:57

address it. Amazing. It's incredibly complex, but

52:59

it's about all we have time for,

53:01

so we will see you next week.

53:04

See you.

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